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Evista Side Effects

Generic name: raloxifene

Medically reviewed by Drugs.com. Last updated on Sep 8, 2023.

Note: This document provides detailed information about Evista Side Effects associated with raloxifene. Some dosage forms listed on this page may not apply specifically to the brand name Evista.

Applies to raloxifene: oral tablet.

Important warnings This medicine can cause some serious health issues

Oral route (tablet)

Increased risk of deep vein thrombosis and pulmonary embolism have been reported.

Women with active or past history of venous thromboembolism should not take raloxifene hydrochloride.

Increased risk of death due to stroke occurred in a trial in postmenopausal women with documented coronary heart disease or at increased risk for major coronary events.

Consider risk-benefit balance in women at risk for stroke.

Serious side effects of Evista

Along with its needed effects, raloxifene (the active ingredient contained in Evista) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Stop taking raloxifene and get emergency help immediately if any of the following effects occur:

Rare

Check with your doctor as soon as possible if any of the following side effects occur while taking raloxifene:

More common

  • bloody or cloudy urine
  • chest pain
  • difficult, burning, or painful urination
  • fever
  • frequent urge to urinate
  • infection, including body aches or pain, congestion in throat, cough, dryness or soreness of throat, runny nose, and loss of voice
  • leg cramping
  • skin rash
  • swelling of hands, ankles, or feet
  • vaginal itching

Less common

  • abdominal pain (severe)
  • aching body pains
  • congestion in lungs
  • decreased vision or other changes in vision
  • diarrhea
  • difficulty in breathing
  • hoarseness
  • loss of appetite
  • nausea
  • trouble in swallowing
  • weakness

Other side effects of Evista

Some side effects of raloxifene may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • hot flashes, including sudden sweating and feelings of warmth (especially common during the first 6 months of treatment)
  • increased white vaginal discharge
  • joint or muscle pain
  • mental depression
  • problems of stomach or intestines, including passing of gas, upset stomach, or vomiting
  • swollen joints
  • trouble in sleeping
  • weight gain (unexplained)

For healthcare professionals

Applies to raloxifene: oral tablet.

Cardiovascular

Other

Musculoskeletal

Respiratory

Dermatologic

Endocrine

Gastrointestinal

Genitourinary

Hepatic

Metabolic

Nervous system

Ocular

Psychiatric

Hematologic

Oncologic

References

1. Cerner Multum, Inc. "UK Summary of Product Characteristics."

2. Cerner Multum, Inc. "Australian Product Information."

3. (2016) "Product Information. Raloxifene (raloxifene)." Prasco Laboratories

Frequently asked questions

Further information

Evista side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.