Edetate calcium disodium Side Effects
Some side effects of edetate calcium disodium may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to edetate calcium disodium: parenteral injection
Side effects include:
Injection site pain.
For Healthcare Professionals
Applies to edetate calcium disodium: compounding powder, injectable solution
Cardiovascular side effects have included hypotension and cardiac rhythm irregularities.
Gastrointestinal side effects have included cheilosis, nausea, vomiting, anorexia, and excessive thirst.
General side effects have included pain at the intramuscular injection site, fever, chills, malaise, and fatigue.
Genitourinary side effects have included glycosuria, proteinuria, microscopic hematuria, and large epithelial cells in urinary sediment.
Hematologic side effects have included transient bone marrow depression and anemia.
Hepatic side effects are mild increases in SGOT and SGPT, which are common, and return to normal within 48 hours after cessation of therapy.
Hypersensitivity side effects have included histamine-like reactions and rash.
Immunologic side effects have included histamine-like reactions (sneezing, nasal congestion, and lacrimation) and rash.
Metabolic side effects have included zinc deficiency and hypercalcemia.
Musculoskeletal side effects have included myalgia and arthralgia.
Nervous system side effects have included tremors, headache, numbness, and tingling.
Renal side effects have included acute necrosis of proximal tubules (which may result in fatal nephrosis) and infrequent changes in distal tubules and glomeruli.
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