Simethicone
Pronouncation: (sih-METH-ih-kone)Class: Antiflatulent
Trade Names:
Extra Strength Gas-X
- Capsules, softgel 125 mg
- Tablets, chewable 125 mg
Trade Names:
Flatulex
- Drops 40 mg per 0.6 mL
Trade Names:
Genasyme
- Tablets, chewable 80 mg
Trade Names:
Genasyme Drops
- Drops 40 mg per 0.6 mL
Trade Names:
Gas-X
- Tablets, chewable 80 mg
Trade Names:
Maalox Anti-Gas
- Tablets, chewable 80 mg
Trade Names:
Mylanta Gas Maximum Strength
- Tablets, chewable 125 mg
Trade Names:
Mylanta Gas Relief Maximum Strength
- Capsules 125 mg
Trade Names:
Mylicon
- Drops 40 mg per 0.6 mL
Trade Names:
Phazyme
- Capsules 180 mg
Trade Names:
Phazyme 125
- Tablets, chewable 125 mg
Ovol Drops (Canada)
Pharmacology
Feedback for Simethicone
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Relieves flatulence by dispersing and preventing formation of mucus-surrounded gas pockets in GI tract.
Indications and Usage
Relief of painful symptoms and pressure of excess gas in digestive tract; adjunct in treatment of many conditions in which gas retention may be problem, such as postoperative gaseous distention and pain, endoscopic examination, air swallowing, functional dyspepsia, peptic ulcer, spastic or irritable colon, diverticulosis.
Unlabeled Uses
Treatment of infant colic.
Contraindications
Standard considerations.
Dosage and Administration
CapsulesAdults
PO 125 mg 4 times daily after meals and at bedtime.
TabletsAdults
PO 40 to 125 mg 4 times daily after meals and at bedtime.
DropsAdults
PO 40 to 80 mg 4 times daily (up to 500 mg/day).
Children 2 to 12 yr of agePO 40 mg 4 times daily.
Children younger than 2 yr of agePO 20 mg 4 times daily (up to 240 mg/day).
Storage/Stability
Store tablets/capsules at room temperature in well closed container. Store suspension at room temperature in tight, light-resistant container. Do not freeze.
Drug Interactions
None well documented.
Laboratory Test Interactions
None well documented.
Adverse Reactions
None well documented.
Precautions
None well documented.
Patient Information
- Advise patient to report any worsening of GI symptoms to health care provider.
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More Simethicone resources:
Gas-X Infant Drops Liquid Drops
Simethicone - Includes detailed dosage instructions.
Gas, Functional Gastric Disorder, Endoscopy or Radiology Premedication, Postoperative Gas Pains











