Simethicone

Pronunciation: sih-METH-ih-kone
Class: Antiflatulent

Trade Names

Bicarsim
- Tablets 80 mg

Bicarsim Forte
- Tablets 125 mg

Extra Strength Gas-X
- Capsules, softgel 125 mg
- Tablets, chewable 125 mg

Flatulex
- Drops 40 mg per 0.6 mL

Genasyme
- Tablets, chewable 80 mg

Genasyme Drops
- Drops 40 mg per 0.6 mL

Gas-X
- Tablets, chewable 80 mg

Maalox Anti-Gas
- Tablets, chewable 80 mg

Mylanta Gas Maximum Strength
- Tablets, chewable 125 mg

Mylanta Gas Relief Maximum Strength
- Capsules 125 mg

Mylicon
- Drops 40 mg per 0.6 mL

Phazyme
- Capsules 180 mg

Phazyme 125
- Tablets, chewable 125 mg

Pharmacology

Relieves flatulence by dispersing and preventing formation of mucus-surrounded gas pockets in GI tract.

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Indications and Usage

Relief of painful symptoms and pressure of excess gas in digestive tract; adjunct in treatment of many conditions in which gas retention may be problem, such as postoperative gaseous distention and pain, endoscopic examination, air swallowing, functional dyspepsia, peptic ulcer, spastic or irritable colon, diverticulosis.

Unlabeled Uses

Treatment of infant colic.

Contraindications

Standard considerations.

Dosage and Administration

PO 125 mg 4 times daily after meals and at bedtime.

PO 40 to 125 mg 4 times daily after meals and at bedtime.

PO 40 to 80 mg 4 times daily (up to 500 mg/day).

PO 40 mg 4 times daily.

PO 20 mg 4 times daily (up to 240 mg/day).

Storage/Stability

Store tablets/capsules at room temperature in well closed container. Store suspension at room temperature in tight, light-resistant container. Do not freeze.

Drug Interactions

None well documented.

Laboratory Test Interactions

None well documented.

Adverse Reactions

None well documented.

Precautions

None well documented.

Patient Information

• Advise patient to report any worsening of GI symptoms to health care provider.

Copyright © 2009 Wolters Kluwer Health.