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Potassium phosphate and sodium phosphate

Generic name: potassium phosphate and sodium phosphate [ poe-TASS-ee-um-FOSS-fate-and-SEW-dee-um-FOSS-fate ]
Brand names: K-Phos Neutral, K-Phos No. 2, PHOS-NaK, Phospha 250 Neutral, Phosphorous Supplement, ... show all 12 brands
Dosage forms: oral powder for reconstitution (250 mg-280 mg-160 mg), oral tablet (250 mg-45 mg-298 mg; 305 mg-700 mg)
Drug class: Minerals and electrolytes

Medically reviewed by Drugs.com on Aug 4, 2023. Written by Cerner Multum.

What is potassium phosphate and sodium phosphate?

Phosphorus is a naturally occurring substance that is important in every cell in the body. The majority of phosphorus in the body is found in the bones. The potassium and sodium salt forms of phosphorus are called phosphates.

Potassium phosphate and sodium phosphate is a combination medicine used to make the urine more acid to help prevent kidney stones.

Potassium phosphate and sodium phosphate may also be used for purposes not listed in this medication guide.

potassium phosphate and sodium phosphate side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Potassium phosphate and sodium phosphate may cause serious side effects. Call your doctor at once if you have:

Common side effects of potassium phosphate and sodium phosphate may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

You should not take potassium phosphate and sodium phosphate if you have severe kidney disease, or high levels of phosphorus in your body.

Before taking this medicine

You should not take potassium phosphate and sodium phosphate if you are allergic to it, or if you have:

To make sure this medicine is safe for you, tell your doctor if you have:

FDA pregnancy category C. It is not known whether potassium phosphate and sodium phosphate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.

It is not known whether this medicine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Potassium phosphate and sodium phosphate should not be given to a child younger than 4 years old without a doctor's advice.

How should I take potassium phosphate and sodium phosphate?

Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take this medicine with a full glass of water.

Potassium phosphate and sodium phosphate works best if you take it with meals and at bedtime.

While using this medicine, you may need frequent blood or urine tests.

The powder form must be mixed with water before you take it. Mix 1 packet of the powder with about 1/3 cup (2.5 ounces) of water and stir until completely dissolved. Swallow the mixture right away after mixing. Do not save for later use.

The tablet form may need to be dissolved in water, or swallowed whole. Carefully follow any dosing instructions provided with your medicine.

If you have a history of kidney stones, it is possible that you will pass old stones after starting treatment with potassium phosphate and sodium phosphate.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Potassium phosphate and sodium phosphate dosing information

Usual Adult Dose for Hypophosphatemia:

1 or 2 tablets/capsules orally four times a day (with meals and bedtime)

Comments:
-As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for adults.

Use(s): Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Adult Dose for Urinary Acidification:

1 or 2 tablets/capsules orally four times a day (with meals and bedtime)

Comments:
-As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for adults.

Use(s): Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Pediatric Dose for Hypophosphatemia:

4 years and older: 1 tablet orally four times a day (with meals and bedtime)

Comments:
-As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for children over 4 and adults.

Uses: Increase urinary phosphate and pyrophosphate; phosphorous supplement

Usual Pediatric Dose for Urinary Acidification:

4 years and older: 1 tablet orally four times a day (with meals and bedtime)

Comments:
-As a phosphorous supplement, each tablet supplies 25% of the US Recommended Daily Allowance (US RDA) of phosphorous for children over 4 and adults.

Uses: Increase urinary phosphate and pyrophosphate; phosphorous supplement

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include numbness or tingly feeling, muscle stiffness or limp feeling, loss of movement, confusion, heavy feeling in your legs, irregular heartbeats, or feeling like you might pass out.

What should I avoid while taking potassium phosphate and sodium phosphate?

Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for your body to absorb potassium phosphate and sodium phosphate.

Avoid taking a vitamin or mineral supplement that contains calcium or vitamin D, unless your doctor tells you to.

Do not use potassium supplements or salt substitutes while you are taking potassium phosphate and sodium phosphate, unless your doctor has told you to.

What other drugs will affect potassium phosphate and sodium phosphate?

Other drugs may interact with potassium phosphate and sodium phosphate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.