Actos (pioglitazone) and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with Actos (pioglitazone) which include:
High Blood Pressure (Hypertension)
Moderate Potential Hazard, High plausibility
thiazolidinediones - edema
Thiazolidinediones can cause dose-related edema. Therapy with thiazolidinediones should be administered cautiously in patients at risk for congestive heart failure as well as those with fluid overload or other conditions that may be adversely affected by excess fluid such as hypertension. Patients should be monitored for signs and symptoms of heart failure such as dyspnea, swelling of legs or ankles, and weight gain. Obesity
Moderate Potential Hazard, High plausibility
thiazolidinediones - weight gain
Thiazolidinediones can cause dose-related weight gain, which may be undesirable in obese patients attempting to lose weight. The mechanism of weight gain is unclear but probably involves a combination of fluid retention and fat accumulation. In postmarketing experience with rosiglitazone, there have been reports of unusually rapid increases in weight and increases in excess of that generally observed in clinical trials. Patients who experience such increases should be assessed for fluid retention and volume-related events such as excessive edema and congestive heart failure.You should also know about...
Actos (pioglitazone) drug Interactions
There are 199 drug interactions with Actos (pioglitazone)
Actos (pioglitazone) disease Interactions
There are 7 disease interactions with Actos (pioglitazone) which include:
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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