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Atomoxetine and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with atomoxetine.

Moderate

Caffeine Atomoxetine

Moderate Drug Interaction

MONITOR: Coadministration of two or more sympathomimetic agents may increase the risk of adverse effects such as nervousness, irritability, and increased heart rate. Central nervous system (CNS) stimulants, particularly amphetamines, can potentiate the adrenergic response to vasopressors and other sympathomimetic agents. Additive increases in blood pressure and heart rate may occur due to enhanced peripheral sympathetic activity.

MANAGEMENT: Caution is advised if two or more sympathomimetic agents are coadministered. Pulse and blood pressure should be closely monitored.

References

  1. Rosenblatt JE, Lake CR, van Kammen DP, Ziegler MG, Bunney WE Jr (1979) "Interactions of amphetamine, pimozide, and lithium on plasma norepineophrine and dopamine-beta-hydroxylase in schizophrenic patients." Psychiatry Res, 1, p. 45-52
  2. Cavanaugh JH, Griffith JD, Oates JA (1970) "Effect of amphetamine on the pressor response to tyramine: formation of p-hydroxynorephedrine from amphetamine in man." Clin Pharmacol Ther, 11, p. 656
  3. (2001) "Product Information. Adderall (amphetamine-dextroamphetamine)." Shire Richwood Pharmaceutical Company Inc
  4. (2001) "Product Information. Tenuate (diethylpropion)." Aventis Pharmaceuticals
  5. (2001) "Product Information. Sanorex (mazindol)." Novartis Pharmaceuticals
  6. (2001) "Product Information. Focalin (dexmethylphenidate)." Mikart Inc
  7. (2002) "Product Information. Strattera (atomoxetine)." Lilly, Eli and Company
View all 7 references

Switch to consumer interaction data

Major

Atomoxetine High Blood Pressure (Hypertension)

Major Potential Hazard, Moderate plausibility

CNS stimulants - hypertension

CNS stimulants increase blood pressure and heart rate; the use of some agents may be contraindicated in patients with severe/uncontrolled hypertension. Caution should be used when administering to patients with preexisting high blood pressure (even mild hypertension) and other cardiovascular conditions. All patients under treatment should be regularly monitored for potential tachycardia and hypertension.

References

  1. (2001) "Product Information. Provigil (modafinil)." Cephalon, Inc
  2. (2001) "Product Information. Dopram (doxapram)." West Ward Pharmaceutical Corporation
  3. (2001) "Product Information. Dexedrine (dextroamphetamine)." SmithKline Beecham
  4. (2001) "Product Information. Didrex (benzphetamine)." Pharmacia and Upjohn
  5. (2001) "Product Information. Tenuate (diethylpropion)." Aventis Pharmaceuticals
  6. (2001) "Product Information. Focalin (dexmethylphenidate)." Mikart Inc
  7. (2002) "Product Information. Concerta (methylphenidate)." Alza
  8. (2002) "Product Information. Strattera (atomoxetine)." Lilly, Eli and Company
  9. (2007) "Product Information. Vyvanse (lisdexamfetamine)." Shire US Inc
  10. (2007) "Product Information. Nuvigil (armodafinil)." Cephalon Inc
  11. (2012) "Product Information. Phendimetrazine Tartrate SR (phendimetrazine)." Sandoz Inc
  12. (2019) "Product Information. Phentermine Hydrochloride (phentermine)." Tagi Pharma Inc
  13. (2023) "Product Information. Desoxyn (methamphetamine)." Recordati Rare Diseases Inc, SUPPL-38
View all 13 references

Atomoxetine drug interactions

There are 335 drug interactions with atomoxetine.

Atomoxetine disease interactions

There are 9 disease interactions with atomoxetine which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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