Zohydro ER Interactions
There are 583 drugs known to interact with Zohydro ER (hydrocodone), along with 16 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 211 are major, 371 are moderate, and 1 is minor.
- View all 583 medications that may interact with Zohydro ER
- View Zohydro ER alcohol/food interactions (1)
- View Zohydro ER disease interactions (16)
Most frequently checked interactions
View interaction reports for Zohydro ER (hydrocodone) and the medicines listed below.
- acetaminophen / hydrocodone
- Adderall (amphetamine / dextroamphetamine)
- amitriptyline
- amlodipine
- baclofen
- Butrans (buprenorphine)
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- docusate
- Fentanyl Transdermal System (fentanyl)
- Flexeril (cyclobenzaprine)
- gabapentin
- ibuprofen
- lisinopril
- Lyrica (pregabalin)
- metformin
- MiraLAX (polyethylene glycol 3350)
- Movantik (naloxegol)
- Norco (acetaminophen / hydrocodone)
- omeprazole
- oxycodone
- pantoprazole
- prednisone
- tizanidine
- tramadol
- trazodone
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Zohydro ER alcohol/food interactions
There is 1 alcohol/food interaction with Zohydro ER (hydrocodone).
Zohydro ER disease interactions
There are 16 disease interactions with Zohydro ER (hydrocodone) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
More about Zohydro ER (hydrocodone)
- Zohydro ER consumer information
- Compare alternatives
- Reviews (52)
- Drug images
- Latest FDA alerts (3)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.