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Tivicay Dosage

Generic name: DOLUTEGRAVIR SODIUM 50mg
Dosage form: tablet, film coated

The information at is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

TIVICAY tablets may be taken with or without food.


Table 1. Dosing Recommendations for TIVICAY in Adult Patients


Recommended Dose

Treatment-naïve or treatment-experienced INSTI-naïve

50 mg once daily

Treatment-naïve or treatment-experienced INSTI-naïve when coadministered with certain UGT1A or CYP3A inducers [see Drug Interactions (7.3) for relevant inducers]

50 mg twice daily

INSTI-experienced with certain INSTI-associated resistance substitutions or clinically suspected INSTI resistancea [see Microbiology (12.4)]

50 mg twice daily

a Alternative combinations that do not include metabolic inducers should be considered where possible [see Drug Interactions (7)].

The safety and efficacy of doses above 50 mg twice daily have not been evaluated.

Pediatric Patients

Treatment-naïve or Treatment-experienced INSTI-naïve

The recommended dose of TIVICAY in pediatric patients aged 12 years and older and weighing at least 40 kg is 50 mg administered orally once daily.

If certain UGT1A or CYP3A inducers are coadministered, then the recommended dose of TIVICAY is 50 mg twice daily [see Drug Interactions (7.3) for relevant inducers].

Safety and efficacy of TIVICAY have not been established in pediatric patients younger than 12 years or weighing less than 40 kg, or in pediatric patients who are INSTI-experienced with documented or clinically suspected resistance to other INSTIs (raltegravir, elvitegravir).