Skip to Content

Tivicay Dosage

Generic name: DOLUTEGRAVIR SODIUM 50mg
Dosage form: tablet, film coated

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

TIVICAY tablets may be taken with or without food.

Adults

Table 1. Dosing Recommendations for TIVICAY in Adult Patients

Population

 
Recommended Dose

Treatment-naïve or treatment-experienced INSTI-naïve

 
50 mg once daily

Treatment-naïve or treatment-experienced INSTI-naïve when coadministered with the following potent UGT1A/CYP3A inducers: efavirenz, fosamprenavir/ritonavir, tipranavir/ritonavir, or rifampin

 
50 mg twice daily

INSTI-experienced with certain INSTI-associated resistance substitutions or clinically suspected INSTI resistancea [see Microbiology (12.4)]

 
50 mg twice daily

a Alternative combinations that do not include metabolic inducers should be considered where possible [see Drug Interactions (7)].

The safety and efficacy of doses above 50 mg twice daily have not been evaluated.

Pediatric Patients

Treatment-naïve or Treatment-experienced INSTI-naïve

The recommended dose of TIVICAY in pediatric patients aged 12 years and older and weighing at least 40 kg is 50 mg administered orally once daily.

If efavirenz, fosamprenavir/ritonavir, tipranavir/ritonavir, or rifampin are coadministered, the recommended dose of TIVICAY is 50 mg twice daily.

Safety and efficacy of TIVICAY have not been established in pediatric patients younger than 12 years or weighing less than 40 kg, or in pediatric patients who are INSTI-experienced with documented or clinically suspected resistance to other INSTIs (raltegravir, elvitegravir).

Hide