Tivicay Dosage

Generic name: dolutegravir sodium
Dosage form: tablet, film coated

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

TIVICAY tablets may be taken with or without food.


Table 1. Dosing Recommendations for TIVICAY in Adult Patients

Adult Population

Recommended Dose

Treatment-naïve or treatment-experienced INSTI-naïve

50 mg once daily

Treatment-naïve or treatment-experienced INSTI-naïve when coadministered with the following potent UGT1A/CYP3A inducers: efavirenz, fosamprenavir/ritonavir, tipranavir/ritonavir, or rifampin

50 mg twice daily

INSTI-experienced with certain INSTI-associated resistance substitutions or clinically suspected INSTI resistancea (12.4)

50 mg twice daily

a Alternative combinations that do not include metabolic inducers should be considered where possible [see Drug Interactions (7)].

The safety and efficacy of doses above 50 mg twice daily have not been evaluated.

Pediatric Patients

Treatment-Naïve or Treatment-Experienced INSTI-Naïve: The recommended dose of TIVICAY in pediatric patients aged 12 years and older and weighing at least 40 kg is 50 mg administered orally once daily.

If efavirenz, fosamprenavir/ritonavir, tipranavir/ritonavir, or rifampin are coadministered, the recommended dose of TIVICAY is 50 mg twice daily.

Safety and efficacy of TIVICAY have not been established in pediatric patients younger than 12 years or weighing less than 40 kg, or in pediatric patients who are INSTI-experienced with documented or clinically suspected resistance to other INSTIs (raltegravir, elvitegravir).