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Lioresal Dosage

Generic name: baclofen
Dosage form: Tablets
Drug class: Skeletal muscle relaxants

Medically reviewed by Drugs.com. Last updated on Apr 3, 2024.

The determination of optimal dosage requires individual titration. Start therapy at a low dosage and increase gradually until optimum effect is achieved (usually between 40-80 mg daily).


The following dosage titration schedule is suggested:


5 mg t.i.d. for 3 days

10 mg t.i.d. for 3 days

15 mg t.i.d. for 3 days

20 mg t.i.d. for 3 days


Thereafter additional increases may be necessary but the total daily dose should not exceed a maximum of 80 mg daily (20 mg q.i.d.).


The lowest dose compatible with an optimal response is recommended. If benefits are not evident after a reasonable trial period, patients should be slowly withdrawn from the drug (see WARNINGS Abrupt Drug Withdrawal).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.