Skip to Content

Medications for Chronic Spasticity

Drugs associated with Chronic Spasticity

The following drugs and medications are in some way related to, or used in the treatment of this condition.

What is Chronic Spasticity: Spasticity is stiff or rigid muscles with exaggerated, deep tendon reflexes (for example, a knee-jerk reflex). The condition can interfere with walking, movement, or speech.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
baclofen Rx C N X 13 reviews
7.0

Generic name: baclofen systemic

Brand names:  Lioresal, Gablofen, Lioresal Intrathecal, Kemstro

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Lioresal Rx C N X Add review
9.0

Generic name: baclofen systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Dantrium Rx C N X 1 review Add

Generic name: dantrolene systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
Gablofen Rx C N X 2 reviews
8.0

Generic name: baclofen systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Botox Rx C N 1 review
3.0

Generic name: onabotulinumtoxinA systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

 
dantrolene Rx C N X 2 reviews
10

Generic name: dantrolene systemic

Brand names:  Dantrium, Revonto, Dantrium Intravenous

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

 
Lioresal Intrathecal Rx C N X 2 reviews
3.0

Generic name: baclofen systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Kemstro Rx C N X Add review Add

Generic name: baclofen systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Revonto Rx C N X Add review Add

Generic name: dantrolene systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
Dantrium Intravenous Rx C N X Add review Add

Generic name: dantrolene systemic

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

 
onabotulinumtoxinA Rx C N 1 review
3.0

Generic name: onabotulinumtoxinA systemic

Brand name:  Botox

Drug class: skeletal muscle relaxants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

 
Showing all

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N The drug is not subject to the Controlled Substances Act.
1 The drug has a high potential for abuse. The drug has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use of the drug under medical supervision.
2 The drug has a high potential for abuse. The drug has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse of the drug may lead to severe psychological or physical dependence.
3 The drug has a potential for abuse less than the drugs in schedules 1 and 2. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to moderate or low physical dependence or high psychological dependence.
4 The drug has a low potential for abuse relative to the drugs in schedule 3. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 3.
5 The drug has a low potential for abuse relative to the drugs in schedule 4. The drug has a currently accepted medical use in treatment in the United States. Abuse of the drug may lead to limited physical dependence or psychological dependence relative to the drugs in schedule 4.
Alcohol
X Interacts with Alcohol.

Browse Drugs by Condition

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Hide