Baclofen Pregnancy and Breastfeeding Warnings
Baclofen Pregnancy Warnings
Baclofen has been assigned to pregnancy category C by the FDA. Animal studies have revealed an increased incidence of omphaloceles. There are no controlled data in human pregnancy. Baclofen should only be given during pregnancy when benefit outweighs risk.
Baclofen Breastfeeding Warnings
Baclofen is excreted into human milk in very small amounts. One lactating woman received a single 20 mg dose of baclofen and 0.1% of that dose was recovered in her breast milk. However, the effect on her infant, if any, was not reported and no other information is available concerning the effect of baclofen in breast-fed infants. Baclofen is considered compatible with breast-feeding by the American Academy of Pediatrics.
References for pregnancy information
- "Product Information. Lioresal (baclofen)." Medtronic Inc, Minneapolis, MN.
References for breastfeeding information
- Committee on Drugs, 1992 to 1993 "The transfer of drugs and other chemicals into human milk." Pediatrics 93 (1994): 137-50
- Eriksson G, Swahn CG "Concentrations of baclofen in serum and breast milk from a lactating woman." Scand J Clin Lab Invest 41 (1981): 185-7
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