Generic name: anakinra
Dosage form: injection, solution
This dosage information does not include all the information needed to use Kineret safely and effectively. See full prescribing information for Kineret.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Active Rheumatoid Arthritis
The recommended dose of Kineret for the treatment of patients with rheumatoid arthritis is 100 mg/day administered daily by subcutaneous injection. Higher doses did not result in a higher response. The dose should be administered at approximately the same time every day.
Physicians should consider a dose of 100 mg of Kineret administered every other day for RA patients who have severe renal insufficiency or end stage renal disease (defined as creatinine clearance < 30 mL/min, as estimated from serum creatinine levels) [see Use in Specific Populations (8.6) and Clinical Pharmacology (12.3)].
Instructions on appropriate use should be given by the healthcare provider to the patient or caregiver. Patients or caregivers should not be allowed to administer Kineret until the patient or caregiver has demonstrated a thorough understanding of procedures and an ability to inject the product. After administration of Kineret, it is essential to follow the proper procedure for disposal of syringes and needles. See the “Information for Patients” insert for detailed instructions on the handling and injection of Kineret.
Do not use Kineret beyond the expiration date shown on the carton. Visually inspect the solution for particulate matter and discoloration before administration. There may be trace amounts of small, translucent-to-white amorphous particles of protein in the solution. The prefilled syringe should not be used if the solution is discolored or cloudy, or if foreign particulate matter is present. If the number of translucent-to-white amorphous particles in a given syringe appears excessive, do not use this syringe.
Administer only one dose (the entire contents of one prefilled glass syringe) per day. Discard any unused portions.