Dextromethorphan/Guaifenesin Dosage

Usual Adult Dose for Cough

Immediate release: 10 to 30 mg dextromethorphan orally every 4 to 8 hours as needed, not to exceed 120 mg/day.
Extended release: up to 60 mg dextromethorphan orally every 12 hours.

Usual Pediatric Dose for Cough

Immediate release:
2 to 5 years: 2.5 to 7.5 mg dextromethorphan orally every 4 to 8 hours as needed, not to exceed 30 mg/day.
6 to 11 years: 10 to 15 mg dextromethorphan orally every 4 to 8 hours as needed, not to exceed 60 mg/day.
12 years or older: 10 to 30 mg dextromethorphan orally every 4 to 8 hours as needed, not to exceed 120 mg/day.

Extended release:
2 to 5 years: up to 15 mg dextromethorphan orally every 12 hours.
6 to 11 years: up to 30 mg dextromethorphan orally every 12 hours.
12 years or older: up to 60 mg dextromethorphan orally every 12 hours.

dextromethorphan-guaifenesin 20 mg-200 mg/10 mL oral liquid:
12 years or older: 1 pre-filled syringe (10 mL) orally every 4 hours, not to exceed 6 doses in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Dextromethorphan-guaifenesin should be administered with plenty of fluids.

See also...