Benzoyl Peroxide/Clindamycin Topical Dosage

Usual Adult Dose for Acne

BenzaClin (R) Topical Gel: Apply to affected areas twice daily, morning and evening, or as directed. The skin should be gently washed, rinsed with warm water, and patted dry before application.

Acanya (TM) Gel: Apply a pea-sized amount to the face once daily. Use beyond 12 weeks has not been evaluated.

Duac (R) Topical Gel: Apply to affected areas once daily, in the evening, or as directed. The skin should be gently washed, rinsed with warm water, and patted dry before application.

Usual Pediatric Dose for Acne

12 years or older:

BenzaClin (R) Topical Gel: Apply to affected areas twice daily, morning and evening, or as directed. The skin should be gently washed, rinsed with warm water, and patted dry before application.

Acanya (TM) Gel: Apply a pea-sized amount to the face once daily. Use beyond 12 weeks has not been evaluated.

Duac (R) Topical Gel: Apply to affected areas once daily, in the evening, or as directed. The skin should be gently washed, rinsed with warm water, and patted dry before application.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Benzoyl peroxide-clindamycin topical is contraindicated in patients with a history of regional enteritis, ulcerative colitis, or antibiotic-associated colitis.

Patients should be advised to discontinue use of this drug and consult a physician if diarrhea or allergic symptoms (such as severe swelling or shortness of breath) develop. Benzoyl peroxide-clindamycin should be discontinued if severe irritation develops.

Contact with eyes, mouth, or mucous membranes should be avoided.

Safety and efficacy have not been established in children less than 12 years old.

Dialysis

Data not available

Other Comments

Benzoyl peroxide-clindamycin gel may be stored at room temperature (up to 77 degrees Fahrenheit) and should be discarded after 3 months (BenzaClin) or 2 months (Acanya and Duac). It should not be allowed to freeze.

Benzoyl peroxide-clindamycin may bleach hair and colored fabrics.

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