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Marinol Disease Interactions

There are 4 disease interactions with Marinol (dronabinol).

Moderate

Dronabinol (applies to Marinol) seizures

Moderate Potential Hazard, Moderate plausibility.

Seizures and seizure- like activity have been reported in patients using dronabinol. Caution is advised in patients with history of a seizure disorder, as dronabinol may lower seizure threshold. Therapy should be discontinued immediately in patients who develop seizures and medical attention should be sought immediately.

References

  1. (2001) "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc
  2. (2017) "Product Information. Syndros (dronabinol)." Insys Therapeutics Inc
Moderate

Miscellaneous antiemetics (applies to Marinol) cardiac disease

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Cardiovascular Disease

The use of some antiemetics such as dronabinol and nabilone has been associated with occasional hypotension, possible hypertension, syncope or tachycardia. Therapy with these drugs should be administered cautiously in patients with cardiac disease.

References

  1. (2001) "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc
  2. (2006) "Product Information. Cesamet (nabilone)." Valeant Pharmaceuticals
  3. (2017) "Product Information. Syndros (dronabinol)." Insys Therapeutics Inc
Moderate

Miscellaneous antiemetics (applies to Marinol) psychoses/depression

Moderate Potential Hazard, High plausibility. Applicable conditions: Psychosis

Some antiemetics such as dronabinol and nabilone may precipitate or exacerbate psychotic symptoms or anxiety, depression, hallucinations or psychosis. Therapy with these drugs should be administered cautiously in patients with a history of psychiatric disorders, emotional instability, or depression, and particularly if they are elderly. Careful psychiatric monitoring is advised.

References

  1. (2001) "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc
  2. (2006) "Product Information. Cesamet (nabilone)." Valeant Pharmaceuticals
  3. (2017) "Product Information. Syndros (dronabinol)." Insys Therapeutics Inc
Moderate

Miscellaneous antiemetics (applies to Marinol) substance abuse

Moderate Potential Hazard, High plausibility. Applicable conditions: Drug Abuse/Dependence, Alcoholism

Some antiemetics as dronabinol and nabilone have a significant potential for abuse. Therapy with these drugs should be administered cautiously in patients with a history of substance abuse. It may be prudent to refrain from dispensing large quantities of dronabinol to these patients.

References

  1. (2001) "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc
  2. (2006) "Product Information. Cesamet (nabilone)." Valeant Pharmaceuticals
  3. (2017) "Product Information. Syndros (dronabinol)." Insys Therapeutics Inc

Marinol drug interactions

There are 395 drug interactions with Marinol (dronabinol).

Marinol alcohol/food interactions

There is 1 alcohol/food interaction with Marinol (dronabinol).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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