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Dronabinol Pregnancy and Breastfeeding Warnings

Dronabinol is also known as: Marinol

Dronabinol Pregnancy Warnings

Use is recommended only if the potential benefit justifies the potential risk to the fetus. US FDA pregnancy category: C

Animal studies have not revealed any evidence of teratogenicity. Adverse effects including decreased maternal weight gain and number of viable pups, and increased fetal mortality and early resorptions were dose-dependent and less apparent at lower doses which produced less maternal toxicity. There are no controlled data in human pregnancy. Animal studies also showed some fertility effects including reduced ventral prostate, seminal vesicle, and epididymal weights and decreased seminal fluid volume, spermatogenesis, number of developing germ cells, and number of Leydig cells in the testis. However, no effect has been observed on sperm count, mating success, and testosterone levels. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Dronabinol Breastfeeding Warnings

Use in nursing mothers is not recommended. Excreted into human milk: Yes Comments: This drug is absorbed by the nursing infant.

One long-term study found that daily or near daily marijuana use might delay a breastfed infant's motor development, but not growth or intellectual development. Other studies found that occasional maternal marijuana use during breastfeeding did not have any discernible effects on nursing infants, but these studies were inadequate to rule out all long-term harm.

See references

References for pregnancy information

  1. "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc, Columbus, OH.
  2. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):

References for breastfeeding information

  1. "Product Information. Marinol (dronabinol)." Roxane Laboratories Inc, Columbus, OH.
  2. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):

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