Phenytoin Alternatives Compared
Phenytoin | Valtoco | Keppra |
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Phenytoin | Valtoco (diazepam) | Keppra (levetiracetam) |
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Prescription only
Prescribed for Seizures, Epilepsy, Status Epilepticus, Cluster-Tic Syndrome, Neurosurgery, Anxiety, Seizure Prophylaxis During or Following Neurosurgery, Arrhythmia, Myotonia Congenita, Peripheral... View more |
Prescription only
Prescribed for Seizures. Valtoco may also be used for purposes not listed in this medication guide. |
Prescription only
Keppra is an anticonvulsant that is used in conjunction with other medications for the treatment of certain types of seizures. It may cause drowsiness but it is less likely than some other... View more |
Related suggestions Popular comparisons
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More about Phenytoin | More about Valtoco (diazepam) | More about Keppra (levetiracetam) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Phenytoin has an average rating of 7.5 out of 10 from a total of 111 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 17% reported a negative effect. |
Be the first to share your experience with this drug. |
Keppra has an average rating of 5.7 out of 10 from a total of 308 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 35% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: phenytoin side effects in more detail. |
See also: Valtoco side effects in more detail. |
See also: Keppra side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all phenytoin prices |
View all Valtoco prices |
View all Keppra prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Di-Phen, Dilantin, Phenytek, Phenytoin Sodium, Phenytoin Sodium, Extended Release | Other diazepam brands include: Diastat, Diastat AcuDial, Diastat Pediatric, Diazepam Intensol, Valium | Other levetiracetam brands include: Elepsia XR, Keppra XR, Roweepra, Roweepra XR, Spritam | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
15 hours |
70 hours |
8 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 833 drugs are known to interact with phenytoin:
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A total of 521 drugs are known to interact with Valtoco:
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A total of 237 drugs are known to interact with Keppra:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
January 06, 1953 |
January 10, 2020 |
November 30, 1999 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.