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Zofran User Reviews & Ratings (Page 5)

Zofran has an average rating of 7.8 out of 10 from a total of 227 reviews on Drugs.com. 76% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Zofran

  • Frequ...
  • Taken for 6 months to 1 year
  • November 19, 2023

For Nausea/Vomiting "I, unfortunately, have extensive experience with hospitals and chronic illness. I currently have a non-healing ulcer and I’m desperately trying to avoid a major, life-changing surgery. I’ve had Zofran in IV form, tablets, and melts. I currently use 4mg melts with the only side effect possible drowsiness. It has been a game changer for me, and I prefer it over Reglan. I give Zofran a 10 out of 10."

10 / 10
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2 Report
  • Zofran...
  • May 1, 2016

For Nausea/Vomiting, Chemotherapy Induced "I had a very long treatment time, 3Xweek, 2 8 hr. sessions with three types of chemo radiation. It was every 3rd week, Wed, Thur, & Fri. Wed/Thur were 8 hr. sessions, Fri, 4 hrs. I was constantly vomiting, morning, noon and night. I took this from the get go, but after about my 2nd session, I threw up a lot in the mornings, or if I coughed too hard even. I know it would have been SO much worse without the Zofran. I think with the amount of treatment I had, both chemo and radiation, to both my chest and to my brain that I was VERY lucky I wasn't more sick, and frankly, I'm lucky to be here at all. Thank you Cancer Treatment center and of course, thank you God!"

8 / 10
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17 Report
  • Makayla...
  • December 31, 2017

For Gastroenteritis "I was diagnosed with GERD at 14 and whenever I feel even slightly nauseous, I suck on a Zofran and the nausea goes away within about 2 minutes. It’s very useful but every now and then if I feel extremely nauseous it doesn’t help much."

9 / 10
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14 Report

Frequently asked questions

  • rache...
  • Taken for 1 to 6 months
  • August 12, 2017

For Nausea/Vomiting "I have hyperemesis gravidarum. Never have I experienced relief with Zofran, minimal, if at all. Constipation goes hand in hand with this drug and I'd rather have N&V all day than be as constipated as I am right now. You have to weigh your pros and cons with this drug, and it's not for me."

1 / 10
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  • Mooney
  • Taken for less than 1 month
  • June 26, 2019

For Nausea/Vomiting "Took Zofran for morning sickness, got a splitting migraine an hour later...bed ridden with it all day. Nausea was gone but I rather it then having a migraine. I do suffer migraines but this medication definitely triggered one for me."

2 / 10
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Are you taking this medicine?

  • savvy...
  • Taken for less than 1 month
  • November 6, 2016

For Nausea/Vomiting "I was given this drug by injection in the emergency room because I had a reaction to another drug. It stopped me from vomiting. However, since Imunetherapy I have become allergic to all nsaids, and several other drugs. One drug for a heart problem I take makes me vomit so they gave me this drug in pill form and well....I threw it up and, and tried again, and threw it up and this went on until I again went to the emergency room. An injection works but the pill works only before you become nauseated. I went to another medicine phenergan and that was a suppository which worked very well."

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  • Penny
  • Taken for 2 to 5 years
  • February 2, 2019

For Nausea/Vomiting "I find Zofran to be totally worthless regardless of format or strength. Not only does it not help but also, it causes constipation that greatly aggravates my existing nausea and abdominal pain even further. I am dealing with that now after a recent ER visit and regretting not having refused it."

1 / 10
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  • Sickly
  • Taken for 1 to 6 months
  • May 30, 2018

For Nausea/Vomiting "I have easily upsettable IBS (irritable bowel syndrome) and this has been a wonder medicine for me. Sometimes when I get up in the morning, I am so nauseous I can not function. The dissolvable tablet leaves me feeling better within a minute. It has also worked when I had the stomach bug. It is working wonderfully now with a depression medicine that I just started taking that has a side effect of nausea and vomiting. I was seconds away from throwing up and quickly popped one of these in my mouth... back to normal within thirty seconds! Zofran is a lifesaver!"

10 / 10
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12 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • October 21, 2012

For Nausea/Vomiting, Chemotherapy Induced "Overall, it has been the best anti-emetic available for chemotherapy induced nausea and vomiting. The downfall is gastric slowdown-- which can become more pronounced if on vinca alkaloid chemo or opioids."

9 / 10
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19 Report
  • Gabzzie
  • Taken for less than 1 month
  • April 20, 2017

For Nausea/Vomiting "It cost me $3 for six tablets with insurance. When I was vomiting every couple hours for a week and was prescribed Zofran, it reduced my vomiting to one or twice a day for the next two weeks as compared to every couple hours. It is now the third week I've been sick, and the drug works within an hour for me. There were a couple days my prescription ran out, and I started throwing up 10 times in a day again. Highly recommend"

9 / 10
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  • MrsP
  • May 29, 2009

For Nausea/Vomiting "This morning at about 1 am I was admitted to ER with uncontrollable vomiting. Literally within seconds of the Zofran injection, the nausea was gone, which says a lot because I was actively vomiting when the injection was given. God bless the men and women who developed this drug. It truly is a miracle."

10 / 10
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23 Report
  • survi...
  • July 19, 2010

For Nausea/Vomiting, Radiation Induced "After radiation my husband could not keep anything down. If he coughed, sneezed, brushed his teeth or just consumed food he would throw up. After taking this drug for three days it has made a world of difference. It is costly but worth the outcome."

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22 Report
  • icono...
  • March 3, 2009

For Nausea/Vomiting "This drug has saved my life at least once. I took it when I was pregnant and had unrelenting morning sickness that wasn't helped by any other medications. I'm now taking it again for nausea caused by severe pain (as well as the nausea caused in turn by pain medications, as I seemingly can't win on that one). But perhaps most importantly, it was the only drug that got me out of opiate withdrawal when I had the stomach flu. Without this, I would have been in the hospital because I couldn't otherwise keep anything down and without opiate therapy the withdrawal and the pain combined could easily have killed me. The only possible drawback is cost; even the generic would be completely out of reach for someone without insurance."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • June 11, 2018

For Nausea/Vomiting "It might have helped a tad with my nausea but I woke up the following day with an excruciating migraine so I won’t be taking this product ever again. If you have a history with migraines or headaches, I probably try alternative methods."

3 / 10
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  • Juju
  • Taken for less than 1 month
  • January 30, 2021

For Nausea/Vomiting "Acute vomiting - was given I V push Zofran. Within minutes a headache ensued. Massive headache which I did not know or was told can be a side effect. Released from ER 2 hrs later MASSIVE MASSIVE HEADACHE! Headache got worse and worse over the next 3 days. Had to then take Excedrine for headache and had instant digestive pain - NEVER EVER IN MY LIFE HAVE I HAD DIGESTIVE PAIN! Within 24 hrs had shoulder pain in both shoulders - that radiated down both arms. Nausea gone and vomit gone next day. Since Tuesday at the ER I am bedridden still on Sat. with massive headache still - shoulder pain and what feels like an ulcer. I'd have been better off living through the vomit. Especially since at 61 yrs old - headache - digestive pain- shoulder pain have never ever been an issue for me."

1 / 10
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  • AlyCat
  • Taken for less than 1 month
  • June 3, 2021

For Nausea/Vomiting "I took Zofran on May 3, 2021 to help my nauseated stomach. After a little while when it kicked in I started feeling very drowsy and tired and my stomach seem like it was hurting worse. I now know that this medication Zofran is not something for me to take. I want to get better not worse."

3 / 10
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6 Report
  • chron...
  • Taken for 1 to 2 years
  • August 16, 2018

For Nausea/Vomiting "This is the only thing that stops my all day vomiting spells. Get the one that dissolves under or on your tongue if you’re like me and vomit every 2-5 minutes and you don’t have to worry about not keeping it down. Kind of a weird taste but not bad by any means. I’m quite certain this pill has saved my life and thousands in hospital visits for when I become dangerously dehydrated from the constant vomiting."

10 / 10
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10 Report
  • Anonymous
  • July 20, 2011

For Nausea/Vomiting "Have been taking this medicine for the past 17 weeks with severe hyperemesis. Have been hospitalized 7 times with dehydration. This was mainly when I had the flu on top of the morning sickness. Zofran is a really great medicine, I'm on 8mg three times a day. Side effects include lack of appetite and constipation. But the benefits far outweigh the risk of not having it. I am able to eat and drink what I need to keep this baby growing and although I am still not able to return to work, I am able to do day to day tasks. In Australia this isn't covered by any insurance at all and for the 8mg they are $120 for 10 tablets so at 3 a day and not being able to work it is costing us a fortune but again on the positive side the baby is healthy!"

9 / 10
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  • Anonymous
  • April 10, 2009

For Nausea/Vomiting "I was given Zofran for ALL DAY morning sickness during pregnancy. It works very well, but causes constipation, stomach cramps, and diarrhea. If I wait at least 12 or more hours between doses the side affects are milder and the nausea is almost completely gone. Before I had this drug I was miserable and missing work."

9 / 10
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20 Report
  • Fran
  • December 20, 2018

For Nausea/Vomiting "I received Zofran for severe nausea for 3 days. It did not work! I was vomiting within 30 min. of each injection. This is supposed to be the wonderful new drug that works for everybody. So I got severely dehydrated. It doesn't work for everybody."

1 / 10
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  • ritzi
  • Taken for less than 1 month
  • April 30, 2014

For Nausea/Vomiting, Postoperative "Was given Zofran for nausea in Recovery Room before going to same-day surgery unit prior to release. Ended up with nausea, dizziness, vomiting & shivering. After 2nd vomiting episode I was given Phenergan & was able to be released in another couple of hours."

1 / 10
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  • Oodle...
  • Taken for 2 to 5 years
  • November 30, 2015

For Nausea/Vomiting, Postoperative "I've been given Zofran pre op and post op for all ten surgeries, including my hysterectomy since I always have nausea and vomiting before/after surgery. I've even got Zofran during ER visits for migraines, gallstones, and ovarian cyst ruptures. This is my go to antimetic and I even have the ODT in my nightstand in case I ever get too nauseous. Amazing drug!"

10 / 10
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  • ycnim
  • June 2, 2009

For Nausea/Vomiting "I began having severe nausea and dry heaving during my pregnancy. Doctor prescribed Zofran, and within minutes the buzz of nausea was gone. Instant relief. It really took the edge off. I highly recommend Zofran."

10 / 10
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19 Report
  • Anonymous
  • May 29, 2009

For Nausea/Vomiting "I've had severe morning sickness with both of my pregnancies. No other medication worked. I've been off work for a week, unable to get out of bed. After only two days on this drug I can finally start living again."

10 / 10
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19 Report
  • Hein
  • October 25, 2013

For Nausea/Vomiting "Took my 2 year old grandson to ER after vomiting/nausea all morning. Zofran was administered. He had seizure within 2 minutes after the drug was administered and another two seizures within 12 hours. Spinal fluid showed no abnormality neither the EEG or the MRI brainscan. Neurologist decided Zofran to have caused the seizures. The amount administered not known but a seond dose were given because " he spit out" the first."

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14 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.