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Zofran User Reviews & Ratings (Page 4)

Zofran has an average rating of 7.8 out of 10 from a total of 227 reviews on Drugs.com. 76% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Zofran

  • Anonymous
  • January 1, 2016

For Nausea/Vomiting "This medication worked wonders when I had my hip scope back in May. I only took pain pills to sleep, but when I went to shower and sat down after taking my pills I was so nauseous and took zofran and it worked within 5 minutes! I actually used it for a hangover once and still worked amazingly! Haha "

9 / 10
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  • sewista
  • June 12, 2015

For Nausea/Vomiting "Post op pain medication was making me vomit. After trying several pain meds, it was decided that I should take 8mg Zofran every 8 hours. The only side effect of this drug was difficulty passing urine after taking it for more than 3 days. We cut it back to two Zofran daily and that seemed to take care of the side effect,"

8 / 10
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  • aaano
  • Taken for 1 to 6 months
  • March 6, 2019

For Nausea/Vomiting "Zofran is incredible. I was prescribed it when I started suffering from constant nausea about three months ago and it has been a lifesaver ever since. It works almost immediately even after taking it for so long and has only not worked twice, both times when I had already eaten fatty or greasy foods and had other meds in my system. It can make you extremely constipated, so make sure you're hydrating yourself and consuming lots of fiber, but other than that I never experienced an adverse side effect or interaction."

10 / 10
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15 Report

Frequently asked questions

  • Rae...
  • December 19, 2009

For Nausea/Vomiting "I have had constant nausea for SEVEN years related to gastroparesis and Meniere's disease (an inner ear disorder causing severe vertigo and nausea). I was finally offered Zofran on my last emergency room trip (I told the doctor if they didn't do something I was going to go insane)... Zofran has been a lifesaver and I never go anywhere without it. And I mean that. It works like magic every time I need it. The longest it has ever taken to kick in is 45 minutes. I can't say enough good things about it. 100% thumbs up."

10 / 10
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32 Report
  • Mule
  • Taken for 1 to 6 months
  • May 22, 2020

For Nausea/Vomiting "Zofran is a total waste of medication. Literally does NOTHING for me. Off brand pepto does better. My wife has been given it several times in the hospital for the same thing. No results. Seems like the hospitals try to force this particular nausea medicine first. I’m guessing because it’s cheaper."

1 / 10
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Are you taking this medicine?

  • Savii
  • December 19, 2016

For Nausea/Vomiting "I had my gallbladder removed in September and have been on this drug (as needed) since. It is a god send. I don't get as nauseated as I was the first month of surgery but still have nausea here and there. This drug works very quickly and I feel instant relief. Sometimes I find myself needing to take 2 doses of the nausea is severe and it helps to ease it. Recommend this for anyone that struggles with nausea."

10 / 10
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19 Report
  • Lee
  • Taken for less than 1 month
  • May 24, 2019

For Nausea/Vomiting "Wow! I went to the ER on Tuesday night and it is now Friday and I was given Zofran for my nausea on top of everything else I was dealing with and this crap has made me nothing but nauseous with lots of throwing up and constipated! Not sure how long this is suppose to last, but it’s freaking annoying and I definitely don’t see myself taking this ever again."

1 / 10
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  • Adam...
  • Taken for less than 1 month
  • November 4, 2017

For Nausea/Vomiting "I got food poisoning and couldn't stop vomiting and having nauseousness from 3 pm to about 4 am. I was puking so much and dry heaving that I was puking up blood (YIKES!). I found some extra zofran in my bathroom cabinet from my doctor from the other month, so I decided to take one 4 mg pill. Vomiting and nausea subsided after 15 min of taking zofran. Zofran, you're a life saver!!! Would always like to carry this Medication around with me all day if I could. Adam"

10 / 10
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  • A god...
  • Taken for 1 to 6 months
  • June 24, 2017

For Nausea/Vomiting "I've been on zofran multiple times. For nausea and vomiting due to a digestive disorder I had, and when I was pregnant (24/7 sickness for most of the pregnancy) For the pregnancy it was okay. It took the edge off. Nothing can ever truly 100% help that level of constant nausea but it kept me from vomiting so I was able to keep down water and food. For the digestive problem causing sickness it was a miracle. Gives me a headache but we'll worth it. Going from feeling so sick to feeling way better. It works wonders."

10 / 10
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  • DaMaF...
  • Taken for 2 to 5 years
  • July 5, 2014

For Nausea/Vomiting, Chemotherapy Induced "Going through chemotherapy for ALL for 3 years, and I've tried EVERY available CNIV that I could get when I was doing my chemotherapy. Zofran by far was the best for me specifically the sublingual (melt under the tongue) it also has a cherry taste to it and the taste of it gives me an almost instantaneously feeling of the symptoms being not as bad and then as it finally melts it greatly reduces the symptom if not completely stops them. Sometimes unfortunately there's times that even though it reduced symptoms that the CNIV was just stronger and I'd still not feel to well and still have CNIV but it did at least help and make it more tolerable when it didn't completely take it away."

10 / 10
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  • Fizzle
  • December 13, 2014

For Nausea/Vomiting "I have been having a lot of stomach issues. I was told it was a bunch of things. At last it took about 4 months to conclude it was my colon. After a bout in the hospital I was given Zofran which worked wonders in no time at all; was also given Phenergan at one point and immediately became extremely irate until I passed out from it. In comparison Zofran is a God send. Can be expensive."

10 / 10
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  • Anonymous
  • October 2, 2011

For Nausea/Vomiting "Zofran is a life saver! Works quickly and very well. I get bad anxiety and worry a lot which causes recent and sometimes unbearable stomach upset. One pill and I'm good! I am so happy I found relief. It does cause constipation for me but I'd much rather deal with that!"

8 / 10
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26 Report
  • Anonymous
  • May 26, 2008

For Nausea/Vomiting "This really is a life saver. I'm 17 weeks pregnant and have cripling morning sickness. So bad that I could not eat or drink anything for over a week. As soon as I took one pill I became 100000000 times better. I would recommend this pill to anyone. I love it. 10 out of 10 in my book."

10 / 10
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31 Report
  • Brit
  • February 2, 2016

For Nausea/Vomiting "Was given this drug while pregnant for morning sickness. Didn't help at all, gave me a headache and actually made me throw up a few times. My son was also born with a genetic mutation - Epidermal Nevus syndrome which I'm sure is from the Zofran as it is not approved for use during pregnancy. If I could go back in time I would NOT have used this during pregnancy. I was also given this drug several times for gastroenteritis with the same result - headache and increased vomiting. Did not work for me."

1 / 10
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  • I...
  • March 29, 2021

For Nausea/Vomiting "Zofran is amazing. Absolutely amazing. My entire life I have feared throwing up. Not sure why but I now have anxiety because of it. I found out I was pregnant and was slightly nauseous all day everyday but with someone who fears vomiting greatly, I was scared and upset. My doctor finally prescribed me zofran after visiting the hospital for nausea and it has been helping me ever since. I have been taking it for 4 years now whenever I need it And it takes it away immediately. So thankful"

10 / 10
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  • Mari-...
  • April 30, 2016

For Nausea/Vomiting "I've been dealing with extreme nausea and vomiting for the past 6 months, and it finally got to the point where I couldn't take it anymore and went to the ER. They gave me Zofran through IV and was feeling better in about an hour. After I was released I was on 4 mg every 8 hours and for about a week I was back to my old self. Then things started to go down hill, and they boosted it to 8 mg. Now it doesn't evenwork anymore and makes me more nauseous than I was before. I also got pretty bad constipation and headaches after taking the medication. Not to mention, if you're taking the tablets be ready to handle the taste because it is DISGUSTING."

5 / 10
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  • Britt...
  • June 18, 2017

For Nausea/Vomiting "I have a variety of GI issues as well as a phobia of throwing up and ever since I've been taking Zofran ODT, I've been able to function without throwing up in the middle of the night every night. My only complaint would be that after 5 years of taking it, it doesn't work as magically as it did at the start, but it still works wonders."

10 / 10
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  • Me r X
  • Taken for less than 1 month
  • November 9, 2015

For Nausea/Vomiting "Zofran is great for nausea, but watch out for the constipation. I was prescribed 15 8mg tablets last week and have used one tablet a day since then (about 5 days now) and after waiting, walking, drinking copious amounts of water, I am going to need to try a suppository, or laxative, and have my dosage of zofran decreased to 4 mg. Great medication, it DOES give me nausea relief, just something to be prepared for, I know I wasn't."

8 / 10
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  • BFOX
  • December 8, 2016

For Gastroenteritis "Zofran is heaven sent. It saved me and my baby's lives. I was sick for 9 months with hyperemesis gravidarum. I was on a zofran pump as well as IV HYDRATION. I don't know if my baby would have survived without it. I'm still using it for chronic nausea. I wish I could personally thank the creators of this drug. Thank you."

10 / 10
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  • John
  • Taken for 1 to 6 months
  • October 7, 2019

For Nausea/Vomiting "So, I suffer from Cannabinoid hyperemesis syndrome (CHS) because of smoking pot for the last 5 years and I have to say, what has helped is Zofran - it is really good at doing what it’s designed to do ( helps nausea and vomiting) and eased the tension on my stomach, been using for a month every day 2 hours before smoking whatever ie concentrates or just bud. The Ondansetron is miraculous and will literally save you a ton of time since when I was constantly vomiting I couldn’t do my daily routine (going to work, hanging with friends) man I couldn’t even move at all, I was constantly in my bed throwing up..."

8 / 10
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  • Zofran...
  • Taken for less than 1 month
  • June 28, 2022

For Nausea/Vomiting "I am having severe digestive issues and we are trying to figure out what it is. Gastritis? Gallbladder attack? (I do have a gallstone) IBS? Ulcer? Just don’t know. I have horrible anxiety and stress when something is wrong with me. That probably adds to the nausea. I get nauseous and it hurts like a gnawing pain. I can’t really eat, it’s miserable. Went to the ER twice and they administered Zofran, let me tell you! It is a miracle drug! Painful nausea gone! I feel so much more calm and the gas/bloating is gone. I didn’t experience any effects. Even if I get sleepy, it’s a welcomed side effect after feeling yucky for days! Give it a try!!"

9 / 10
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  • GCano
  • Taken for 1 to 2 years
  • January 15, 2019

For Nausea/Vomiting "Since a child I’ve always been nausea prone. Sometimes there would be a direct correlation such as motion (car more often) sickness, over eating/ unhealthy eating, etc. Mostly it just comes out of no where and stops me in my tracks. Without insurance it was very expensive (not sure how much, but $$$). Ever since having insurance and paying a few dollars I will never be caught dead without a couple tabs on my person!!! My GI was very understanding and prescribed 60 tabs a month (up to 2 a day) with a generous amount of refills!!! Only once did it not work but that was on New Years and I believe for obvious reasons!! I’ve not really noticed side effects since my nausea throws off my body anyway. I take this med at least once a week. I can’t believe I wasn’t introduced to this sooner!!!!!!! It’s saved my life"

10 / 10
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  • Lorilo
  • Taken for less than 1 month
  • July 16, 2019

For Nausea/Vomiting "I caught a stomach virus last winter and was vomiting repeatedly. I couldn't keep anything down. I was nauseous, dizzy,and feverish. I felt like I was on a moving boat and I couldn't move or even think without vomiting. After I threw up bile the 2nd day, I went to the ER. I vomited in the waiting room and 3 more times in the exam room. I was given Zofran, which helped a lot. I only threw up 2 or 3 more times after that. I was diagnosed with norovirus."

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  • Anonymous
  • Taken for less than 1 month
  • December 13, 2012

For Nausea/Vomiting "My daughter was experiences a constant unexplained ache in her stomach and a feeling that she was going to throw up, that no stomach test could find. 3 months later an MRI showed she had an AVM in her brain. Surgery to repair took all symptoms away. 3 years later she started having the same feelings. Found out the feeling of throwing up was the aura before partial seizures they didn't know she was having. Still was having the gnawing ache. One amazing doctor suggested Zofran...it was our miracle. She has been fine ever since."

10 / 10
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  • NormT
  • Taken for 1 to 6 months
  • April 3, 2018

For Nausea/Vomiting, Chemotherapy Induced "I'm one of those people that would rather be in pain than nauseous, so when I started chemotherapy I knew I was in for a ride. I was given a cocktail of meds right before chemo and then Decadron and Zofran for a couple of days after for allergic reaction and nausea. For the times after that "as needed" I have Zofran & Compazine for nausea and Ativan for "anticipatory nausea". I guess the Ativan would help some commenters in this thread who actually get sick from thinking about getting sick. It made me too drowsy so I was left with the Compazine and Zofran. I found the Zofran to be by far the most effective; I take one 4mg tablet as soon as I start feeling queasy and within 10-15 minutes I am fine - I'm even able to eat. Thankfully my insurance covers it as it is a little more expensive than some meds for nausea but to me it's worth not vomiting. I recommend this medication highly."

9 / 10
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14 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.