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Ondansetron User Reviews & Ratings (Page 3)

Ondansetron has an average rating of 7.7 out of 10 from a total of 480 reviews on Drugs.com. 73% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Ondansetron

  • Uniqua
  • Taken for less than 1 month
  • February 3, 2016

Zofran ODT (ondansetron) for Nausea/Vomiting "Today I went to the doctors for some common flu symptoms. They prescribed me Zofran for my nausea and upset stomach. About 10-15 minutes after taking it there was a tremendous relief of everything. It works rapidly and does wonders. I have not experienced any side effects like headaches or nothing yet so everything's good so far."

10 / 10
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  • Pat
  • Taken for 2 to 5 years
  • January 7, 2020

Zofran (ondansetron) for Nausea/Vomiting "I have tried 3 different forms of Zofran on multiple occasions for 2 different reasons, and it has never helped my nausea at all. I have tried it for both my everyday nausea and my migraine nausea, but I would still throw up. I have tried the medication in the forms of: 1. Swallowing the pill 2. Dissolving the tablet in my mouth 3. Getting it pumped into me intravenously (with an IV in the hospital). Zofran just doesn't work on me I guess! It works really well for some people, though."

1 / 10
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  • Greys...
  • Taken for 1 to 2 years
  • January 16, 2017

Zofran (ondansetron) for Gastroenteritis "I sufffer from ulcers & get acid indigestion all the time. Of course with that I experience nausea daily..... when it gets too intense I take a 4 mg zofran and within 20-30 minutes it subsides. I thank God this medicine was created!! In the beginning I would get constipated for about 24 hours after taking a pill but don't have that anymore. I am thankful for this medicine bc I HATE nausea/vomiting."

10 / 10
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Frequently asked questions

  • Thela...
  • Taken for 1 to 6 months
  • April 19, 2019

Zofran (ondansetron) for Nausea/Vomiting "I was prescribed ZOFRAN a few months back, I have suffered from nausea since I was 17 (I'm 36 now). This is the only drug that has ever worked for me, all the other over the counter meds just make the nausea worse, this makes my nausea go away with in 30 mins. and keeps it gone for 8 hours, I wish this had been around when I was younger."

10 / 10
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  • Wildf...
  • September 23, 2013

Zofran ODT (ondansetron) for Nausea/Vomiting "I suffer from chronic lower back pain due to scoliosis and arthritis (42 yrs old). I also suffer from Irritable Bowel Syndrome. I take Zofran almost daily to deal with the miseries of both lower back pain and digestive issues. I still have regular bouts of vomiting, however, Zofran will stop the pain and nausea that would continue for days and land me in the hospital with an IV delivering morphine into my system to stop the cycle of vomiting, nausea, and severe pain. I love my Zofran! It makes life "livable.""

10 / 10
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Are you taking this medicine?

  • Joy
  • Taken for less than 1 month
  • August 21, 2020

Zofran (ondansetron) for Nausea/Vomiting "I have gastritis and am going through a flareup now. Very sick...nauseous for 8 hours every day. Zophran doesn't help me at all...even doubling dose, as my dr recommended. He is giving me Reglan. Praying that works. Nausea is the worst!"

1 / 10
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  • OLou
  • Taken for 1 to 2 years
  • May 3, 2014

Zofran (ondansetron) for Nausea/Vomiting "This medication works wonders for me whenever I feel sick or nauseous. The flavored tablets that disintegrate under the tongue or in the mouth are very convenient and work really quickly to relieve nausea/vomiting. The only real side effect from it that I have noticed is a slight tired feeling. I'd much rather feel a little sleepy than sick to my stomach. I really recommend this medicine if your doctor also feels that it is right for you."

10 / 10
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  • Ginger
  • Taken for 6 months to 1 year
  • February 4, 2021

Zofran ODT (ondansetron) for Nausea/Vomiting "I have extreme anxiety which causes me to have stomach issues to be constantly nauseous. I love this medication but the only side effect I have is constipation but I usually just take a Senakot or just eat the Fiber 1 bars. It works quickly. Doesn't taste the best but absolutely worth it"

10 / 10
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  • asbeen
  • Taken for 6 months to 1 year
  • August 22, 2014

Zofran (ondansetron) for Nausea/Vomiting "I've had reoccurring nausea for over a year now. The bouts of nausea, dry heaving and vomiting only bile would last for hours. Phenergan did nothing, but Zofran, within 5 min (usually) I'm cured. It does make you sleepy, but well worth a little tiredness. It is expensive without insurance."

10 / 10
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  • Goldy
  • Taken for less than 1 month
  • February 25, 2020

For Nausea/Vomiting "Used 1 dosage for horrible nausea either caused by food poisoning or an intestinal virus. I was writhing around on my bed like Linda Blair in the Exorcist and took 1 x 4 mg Pill. The nausea literally subsided within about 2 minutes. I am one to whine about the profits of big pharma but bless the folks that came up with this. Wish I knew about this 20 years ago after eating a bad oyster and spent 3 days in bed..also a shout out to you pregnant mothers that deal with nausea..it’s the absolute worst.."

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • November 1, 2015

Zofran (ondansetron) for Gastroenteritis "Like one of the reviews above. I Went into ER with gastroenteritis symptoms. Could not keep down anything including water due to nausea and heavy vomitting of anything. Was given injection of zofran and a prescription for the generic ondansetron and felt less nauseous. Allows me to eat better and to sleep."

9 / 10
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  • Bella...
  • November 7, 2017

Zofran (ondansetron) for Nausea/Vomiting "This drug has saved my sanity. I was undiagnosed with a debilitating vomiting sickness. In hospital at least once a week via ambulance. Repetitive vomiting and could not stop. To the point where I would become unresponsive. After about a month into my undiagnosed sickness, at the emergency room, a nurse gave me a wafer of Zofran. It was a huuuuge relief as my uncontrollable vomiting stopped within 10 minutes. I had not heard of the drug but after finally been diagnosed, after 6 months, as having Severe Idiopathic Gastroparesis I found my new best friend. As well as having a kidney transplant and taking a bucket full of anti-rejection meds, I was soooo grateful that some smart cookie out there invented this drug. Saved my life"

10 / 10
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  • Anonymous
  • October 10, 2012

Zofran (ondansetron) for Nausea/Vomiting "I can't say enough about Zofran. I was curled in a fetal position in front of the bathroom, on the floor, in a cold sweat after vomiting for the last two hours. The last bout was dry heaving. Still the nausea was crippling me. My wife gave me one pill and within 30 minutes the hell I was going through broke like an ocean tide receding. I keep Zofran in the medicine cabinet now, at all times."

9 / 10
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  • Chris...
  • Taken for less than 1 month
  • April 5, 2016

Zofran (ondansetron) for Nausea/Vomiting "I was taking Zofran for awful stomach upset with nausea because one of my other medicines I was on I picked up at pharmacy was a generic new form of medication to treat pain. This new medicine made me very sick. Zofran helped out a lot plus I could take it up to four times per-day. However, I'm also on Lexapro for depression and panic attacks. One day after 2 weeks on these meds I had severe shaking happening to me and I never felt this way before.. Come to find out taking both the Zofran and Lexapro on same day each day was high risk of a drug interaction very severe and I was having the symptoms of a bad interaction. I need to change my lexapro to another type of depression med. But, every depression med is bad with zofran."

8 / 10
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  • 2sick...
  • December 9, 2010

Zofran (ondansetron) for Gastroenteritis "My son is 8 yrs old and could not hold anything down. The doctor gave him Zofran and he began to have hallucination! Well come to find out he is the 27 reported case in the U.S. He had to be sent to a children's hospital. My daughter is 2 and had Zofran she did really well. She did a complete 360 in minutes. Just goes to show how everybody is different."

5 / 10
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  • Sugah
  • Taken for 6 months to 1 year
  • October 6, 2019

Zofran (ondansetron) for Nausea/Vomiting "I have several chronic conditions and one is called Cyclic Vomiting Syndrome. It's even worse than it sounds. I'm over 40 and have suffered since childhood. Gravol stopped working over a decade ago. Last December was particularly bad with many trips to the ER and I finally got lucky and was given this. It's a miracle drug for me about 95% of the time. I do get some side effects like diarrhea and sweating but they're very bearable. I don't go anywhere without a bottle of these."

10 / 10
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  • swinlin
  • Taken for 5 to 10 years
  • September 13, 2020

Zofran (ondansetron) for Nausea/Vomiting, Chemotherapy Induced "I went through pure nightmare during chemo for my Triple Negative BC in 2015. Nausea is an understatement. My oncologist told me that I was the worst patient she ever had with nausea. This is a woman who was practicing in the 70's when they still treated with mercury. I cannot tell you how many nausea medications I was prescribed. Zofran was by far the BEST medication at relieving my symptoms. 5 years later I still cannot 'handle' any kind of nausea. I have an 'emergency' prescription that I have with me 24/7. I only need it maybe twice a year, but it is still the Magic Bullet that relieves any nausea/vomiting I may have. I HIGHLY RECOMMEND THIS MEDICATION!!!"

10 / 10
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  • Kaydubs
  • Taken for 2 to 5 years
  • January 26, 2016

Zofran (ondansetron) for Nausea/Vomiting "Zofran is a miracle drug! I've had this medication for several years on an as-needed basis. With my IBS and anxiety, I tend to get nauseous easily. Whatever the cause to my nausea may be, Zofran works every single time. Now that its dissolvable it makes it so much easier to take. The relief happens within 20-30 minutes and usually 1 tablet is all I need. I do experience 2 side effects each and every time: a painful headache after the drug wears off (6-8 hours after taken) and constipation (practically nonexistent bowel movements) for 2-3 days. For the headache, OTC migraine meds work best. The constipation isn't bothersome enough to me to treat."

10 / 10
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  • Nicck
  • Taken for 2 to 5 years
  • February 4, 2019

Zofran (ondansetron) for Nausea/Vomiting "Zofran is THE most reliable medication I have ever taken! It has prevented me from throwing up, or even feeling nauseas 100% of the time! It's sad that when I was growing up in the 1970's, all I could take for nausea was Pepto-Bismal, which NEVER worked to prevent me from getting nauseous or vomiting. Pepto-Bismal is great for diarrhea, but it did NOTHING for my nausea. I can't say enough about Zofran!"

10 / 10
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  • Bugsy
  • November 3, 2016

Zofran (ondansetron) for Gastroenteritis "The best little white angel pill ever, I have been feeling ill for seven days until today I decided to get help and went to a little clinic and got prescribed zofran, it must be made in heaven because that little pill worked in minutes, I went from 20% to 70% real quick. I work at a job that doesn't allow you to call in, so this pill will be saving me from losing 8 hours on my pay check. Stomach bug sucks and was tired of feeling hungry/sick every ten minutes. Thank you my white angel."

10 / 10
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  • Groba...
  • Taken for less than 1 month
  • April 23, 2018

Zofran (ondansetron) for Gastroenteritis "I’ve been sick with the stomach flu since last night. Ate dinner, then a couple of hours later was in the bathroom throwing up with major diarrhea. Stayed on the toilet literally all night. It was one of those “one little move and you feel like you’re going to throw up” times. Well, once morning came the puking stopped, but I was still really nauseous with dry heaves. So I called my doctor to see if there was anything I could take, and they recommended Zofran. Wow is this a miracle drug! My nausea was gone within 10-15 minutes of taking it, and I was even able to hold down a couple of popsicles and water with it, until about an hour and a half ago when I started feeling nauseous again (the meds were wearing off, so I took another one, and within 10 minuets my nausea was gone! I even ate another popsicle and downed a little juice glass of water and didn’t throw up! If this little white, grape flavored pill isn’t magic, then I don’t know what is!"

10 / 10
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  • Chels...
  • Taken for 1 to 6 months
  • December 29, 2016

Zofran (ondansetron) for Nausea/Vomiting "I used to take Requip for restless leg syndrome, and sometimes it made me so sick I would vomit. Other nights it would be fine. One day I decided to call my PCP for a script of zofran or phenergan to help subside the horrible nasty vomiting and nausea effects of Requip and they wrote me a script of 12 4mg Zofran swallowable tablets. It helped almost immediately (not within a minute, but 10mins or less) and then decided to stop my Requip medication because just made me sick. My RLS went away with other meds that I take and while I still take Zofran, I enjoy it for any spur of the moment "IM GONNA BE SICK" Kind of feeling, so I always carry it with me. At a hospital visit they gave me a dissolvable one that tasted like berries. Good med"

10 / 10
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  • Ddave...
  • May 5, 2017

For Alcohol Use Disorder "In my chequered relationship with alcohol (35 yrs) I have found my way back to sobriety crippled with nausea and vomiting many times. I have tried the usual suspects over the years. Medicines which increase motility (emptying of the stomach more quickly) right up to phenothiazines (used to relieve amongst other things sea sickness and psychosis. Google anti-emetics. If you want to get sober, do it over a one week to ten day period with family support (probably more important than any drug) ask your Doctor for a serious anti sickness drug , keep hydrated !!! Drink ginger tea ! And rest. Good luck, my advice was sound for me. God Bless Dave. X"

7 / 10
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  • Vomit...
  • June 25, 2016

Zofran (ondansetron) for Gastroenteritis "Spent a week vomiting and with diarrhea. Couldn't keep anything down and was getting worse instead of better. I ended up driving to the ER with a vomit bag to my face trying not to crap myself. When they gave me the Zofran, I felt better in 5 minutes and was able to eat a little plain chicken and rice with broth a couple hours later. I didn't realize just much nausea I had until the whole room suddenly stopped waving. Slept better than I have in a long time and this morning I didn't throw up! Crackers and Gatorade for breakfast! Every 6 hours and I love this little pill."

10 / 10
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  • jap
  • March 8, 2016

Zofran (ondansetron) for Nausea/Vomiting "I love this medication, it has made such a difference in my life. I was on the Zofran pump while pregnant for hyperemesis gravidarum, it is the reason I was able to carry my child to term. It is the reason we are both here today. I continue to take Zofran as needed for nausea stemming from complications with fibromyalgia, ibs and celiacs. It can cause constipation from time to time, but that is much easier than nausea and vomiting all the time. It melts quickly and within minutes the nausea is gone."

10 / 10
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27 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.