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Naloxegol User Reviews & Ratings (Page 5)

Brand names: Movantik

Naloxegol has an average rating of 4.9 out of 10 from a total of 269 reviews on Drugs.com. 37% of reviewers reported a positive experience, while 48% reported a negative experience.

Reviews for Naloxegol

  • Do...
  • Taken for less than 1 month
  • July 1, 2017

Movantik (naloxegol) for Opioid-Induced Constipation "Do not try this medication I honestly thought I was going to die 2 hours in the toilet coming out both ends. My toilet looked like something out of a horror film. I literally felt like I was going to die. Being a female the cramps felt like labor contractions, worst pain of my life. This medication needs to be turned in to the FDA!!! Humans should not be their science pigs for this drug. Especially being that we are put on this because we are already in pain- this drug is like taking a death pill!!!! Dangerous! Please stick to an over the counter medication for constipation, I would rather be constipated any day than go through what happened to me. I gave this medication 2 weeks and one night woke up with cramps like I was in labor!!!!!!!!!!!"

1 / 10
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  • Amber
  • Taken for less than 1 month
  • July 13, 2018

Movantik (naloxegol) for Opioid-Induced Constipation "I will NEVER EVER take this medicine. I took one pill last night after taking 180mg of morphine a day I've never been in so much pain in my life. EXPLOSIVE DIARRHEA AND A LOT OF VOMITING. I literally threw up everything in my body including my morphine - for 18 hours straight I was in excruciating pain and withdrawals because every time I took my meds again I threw them up. I couldn't even keep down xanax to help with anxiety Please be aware it will relieve your constipation but you will be cleaning your bathroom floor, sink and toilet when you finally feel better. I agree with whoever said I wouldn't give this to my worst enemy"

1 / 10
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  • No...
  • Taken for less than 1 month
  • August 26, 2016

Movantik (naloxegol) for Constipation, Drug Induced "my advice on movantik is understand that movantik is an opioid blocker in the same manner that naloxone (found in suboxone) is an opioid blocker. My husband took 12.5mg and was thrown in withdrawal. Nausea first, chills, fever, shaking so hard the bed was vibrating. I thought movantik worked on the backed up s**t but it stops the opioid from working. Of course you will have diarrhea when your pain meds are cut off. It may not happen to everyone but it happened to my husband. I guess it's back to OIC"

1 / 10
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Frequently asked questions

  • Compl...
  • July 18, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I have been on opioids for over 10 years and have always had a problem with constipation. I have used several over the counter stool softeners which rarely worked. I could sometimes go almost a week before having a bowel movement. I continue to live with this issue until my doctor recommended'Movantik. He provided me with samples which I started immediately. This drug is a miracle!! i have had a BM almost every day. I have not had any side effects and I feel great"

10 / 10
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  • Opiat...
  • Taken for less than 1 month
  • February 17, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I've been on opiates for many years because of lumbar scoliosis with multiple failed back surgeries. As of the last 5 or 6 months, my constipation worsened to the point where NO laxatives were effective. My bowels had almost stopped working. So far, after 3 weeks on Movantik, I have a regular BM almost every day. I do have to use a little Milk of Mag and a stool softener and eat oatmeal to help it along but, I am SO much better! I am grateful for this drug but it is VERY expensive. I had to make a choice on whether to stay unclogged or take a camping trip to Big Sur. I chose to be unclogged. Sad, I know but health comes first. Hopefully, I will get an authorization soon. I am not impressed with Obama Care ."

9 / 10
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Are you taking this medicine?

  • Nurse...
  • August 5, 2017

Movantik (naloxegol) for Opioid-Induced Constipation "I have been dealing with chronic pain for over 5 years, in which I've had to take opioids on and off. After 3 failed surgeries in attempt to relieve my pain, I decided to see a pain management Dr. who has put me on a daily regimen of opiates. I've tried Amitiza, Linzess, and of course fiber, Miralax, laxatives and enemas. None of these have worked like Movantik. It's been truly a miracle drug. I take it first thing in the morning with my other meds and coffee, but I don't eat until an hour later as the directions say, and it works every time. I've never had diarrhea, horrible stomach cramps, nausea, etc. It just makes me have a large, normal and complete BM in the morning and that's it. It's been a life saver for me."

10 / 10
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  • Horri...
  • Taken for less than 1 month
  • July 15, 2019

Movantik (naloxegol) for Constipation, Chronic "This stuff is horrible!! I took 1 dose 25mg, within 30-40 minutes I started getting really gassy stomach really distended then the abdominal pain and cramping started it was the worst thing I have ever endured almost went to the hospital it was so incredibly bad. Sweating, yawning explosive diarrhea. After 24hrs the cramping and extreme pain have subsided significantly but still have a little. By 36hrs my stomach feels really bloated but most of the other side effects have subsided Thank God! I tell you that was the WORST experience I have ever endured, No One should take this toxic poison"

1 / 10
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  • EllieOh
  • April 24, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Ive been in pain management for 6 years & serious constipation started 2 yrs ago. Linzess & Armitiza did not work. I was stuck using enemas and self manual removal. Awful - and takes time. I have drank 3 Magnesium Citrates with no BM! Movantik works but insurance won't pay. so I take 1 / week from the few samples I get. The pain that starts within an hour of Movantik is the worst I've experienced: doubled over at the gut: crying like it could be anER problem. But I am doubtful of ERs so I try to make myself comfortable at home while I empty for 5-24 hours. Bloated completely uncomfortable and must plan to do nothing until the BMs end. do feel a little withdrawal so I take meds. Movantik is my only option Wish it was more gentle."

5 / 10
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  • Greg
  • Taken for less than 1 month
  • July 8, 2017

Movantik (naloxegol) for Constipation, Drug Induced "My pain management doc has me on time release morphine for spinal injuries because other modalities have not worked. Of course, I have severe constipation. Was given samples of Movantik. I took one pill and within one half hour, had severe cramping and within one hour, total diarrhea. Also had some withdrawal symptoms. I waited a few days, became constipated again and thought I would try it again. Same effect again except this time, I am three days out from taking the Movantik and I am still experiencing withdrawal symptoms...nervousness, runny nose, anxiety, headache and nausea. I have reported the adverse reactions to my doc and will be reporting them to the FDA as well. I am a 67 year old male."

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  • Cocol...
  • Taken for less than 1 month
  • May 2, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I was surprised when I read all the comments about the side effects, I should have read this site before I took Movantik. I also though I was going to die, I had all the side effects listed here. I'm afraid to take it again. I'll try cutting the pill to a quarter and see if it works without the side effects.. I will keep you posted."

5 / 10
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  • prime...
  • Taken for less than 1 month
  • May 21, 2017

Movantik (naloxegol) for Constipation, Drug Induced "The terrible withdrawal symptoms listed in most of these reviews are enough for me to skip the trip to doc and try Movantik. The way to go, at least for me (have fentanyl patch and breakthrough opioids for over 10 years). Get MIRALAX but buy the generic brand, you get 3 huge bottles for about $22 bucks. I didn't personally take Movantik, after reading these reviews I wanted to provide an option for all of you who go through the opioid induced constipation. It is sooo bad and hurts soo much. I take the generic MIRALAX, every day without fail. I also take the 100mg docusate (over the counter now) one at night and morning. It has worked very well and my constipation was soo bad. Of course check with your doc before using."

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  • jnla
  • Taken for less than 1 month
  • August 3, 2018

Movantik (naloxegol) for Constipation, Drug Induced "I've been on opioids for severe neck, and back pain (post-surgical) for more than 10 years. My gastro tested me on several drugs for constipation without success. Movatik was the least expensive and actually created a serious BM* within an hour. *Unfortunately, I experienced severe cramping, sweating, lightheadedness, exhaustion during and 1 hour after. I won't take Movantik every day due to cramping, sweating, weakness, but I can endure the pain once a week. * In all fairness I started Oxygenated Magnesium 07 (magnesium oxide) from a health shop- 3 at night. Mag 07 gave me one BM every 3 days. If I take 4 Mag 07 at night I have a decent BM the next day. Nowhere as significant as Movantik - but NO cramping sweats, etc. Mag 07 may well have set the stage for success with Movantik. I'll stay with Mag 07 and Movantik only once a week. For me, this is a magic combination."

7 / 10
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  • zagor
  • Taken for less than 1 month
  • March 22, 2018

Movantik (naloxegol) for Opioid-Induced Constipation "After 5 years of severe constipation I bought Movantik $200 (my insurance might pay back and cover future costs if approved) and I took it the first day I had small, kinda wet BM. The next day I took it I had a normal bowel movement and it does not make me panicky or whatever except I get some abdominal pain and bloating that is mild and doesn't last short. I would give it 10/10 if it, as I hoped, flushed my colon out but this is still good. And it doesn't even push me to poop so if I as in a place with no toilet I could easily hold it."

9 / 10
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  • john
  • Taken for 1 to 6 months
  • October 25, 2015

Movantik (naloxegol) for Constipation, Drug Induced "Tried OTC and nothing worked. This worked quickly for me and has now continued to work for 5 weeks. Have read this board re side effects of others, but that has not been my experience. Read the label and talk to your doc -- looks like overall the experience of bad side effects is rare for patients who try this med, but talk about it with your doc -- for me this has worked where nothing else did."

10 / 10
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  • lovel...
  • Taken for less than 1 month
  • May 30, 2018

Movantik (naloxegol) for Opioid-Induced Constipation "I am never taking Movantik again. I'm sitting here with a heating pad and the air conditioning on, with a huge blanket on me and let me tell you it gave me the worst excruciating pain in my stomach. I myself have gone to the ER for lesser pain as well. This is out of this world kind of pain I thought I was going to throw my dose up. I almost puked on the nurse lol. I held that medicine down but I seriously wouldn't recommend it to my worst enemy"

1 / 10
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  • love...
  • Taken for less than 1 month
  • December 19, 2016

Movantik (naloxegol) for Constipation, Drug Induced "This is crazy, today is my 4th day in a row to take movantik and no effects. On the first day I went to the bathroom and nothing since. No pain, no poop, no nothing! Weird huh. But I will tell you AFTER I had taken my first dose I started doing some reading on the med and OMGOSH I read some horror stories so immediately I prayed that the med would have no bad effect on me and It has not had one single pain or bad effect on me and its the fourth day so think all is good And although I've only pooped one time my bloating had subsided greatly, ooooh and bloating was a HUGE issue for me. I will update in a week or so. "

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  • Molly...
  • June 19, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I had been backed up literally for a year. Little drubs and drabs finally resorting to medical marijuana for pain, which did not work for my back pain, but somewhat stimulated my bowels not nearly as needed though just enough to break the agony. Was prescribed Movantik 25mg the first day I called 911 I thought something was severely wrong, it was the medicine doing it's job. after what seemed to be hours I was done until the next day and still pretty much the entire month. The 25mg was too strong so I take 12.5 It took a good month to finally adjust. Yes it hurt at first my bm was hard as a rock, but but after all is said and done I have a normal life, I can eat now too! Oh I am on 60 mg methadone 30mg hydro codons. Good Luck, it works."

9 / 10
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  • Victo...
  • July 15, 2019

Movantik (naloxegol) for Constipation, Drug Induced "I have Raynaud's I have rheumethoid arthritis and I also have fibromyalgia therefore I'm prescribed opioids which everyone knows cause constipation. Movantiks is a life saver. Although it's says take one a day it's my belief it should only be taken when you can't go. Yes you will have cramps and sweating but ultimately this medicine works and I would recommend it to anyone."

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  • Orand...
  • Taken for less than 1 month
  • March 2, 2017

Movantik (naloxegol) for Constipation, Chronic "My doctor is insisting I start taking this in spite of having NOOO problem AT ALL whatsoever with what I am taking now !! I have had OIC for 20 years. This Movantix has a huge risk of side effects. I take a dose of miralax and one stool softener ( ducosate CALCIUM ,NOT ducosate SODIUM ) and PROBLEM SOLVED for years!!!!! If I eat a lot of bread I take extra ducosate calcium pill. NO SIDE EFFECTS WHATSOEVER !!! Every time I see a TV commercial for all of these prescription laxatives I cringe. Why take meds with side effect worries??? My new doctor is adamant that I try this Movantik when I don't need to switch what works!!"

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  • Billy
  • February 17, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Ditto on every negative review I've read about this drug. I have had severe hemorrhoid swelling, burning and pain caused by the pressure of OIC. Although this drug was effective, the nightmare which preceded relief far outweigh ever taking this Big Pharma disaster. A mule couldn't tolerate this drug."

2 / 10
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  • Lee
  • Taken for less than 1 month
  • April 2, 2017

Movantik (naloxegol) for Constipation, Drug Induced "Been on opiates for 10 years, broke my back had a fusion and have basically suffered since... talked to doc about the med the 1st two times I was amazed and sooo happy to have relief.. 3rd time I took it I was in withdrawal and couldn't go to work it was so bad :(. And I took it at night all 3 times. I'm so disappointed that it did this. I'm scared to take it again but now again back to being stopped up "

2 / 10
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  • Patient...
  • Taken for 1 to 2 years
  • June 21, 2019

Movantik (naloxegol) for Opioid-Induced Constipation "Not a Doctor... Long term Opioid use... on Movantik for over 18 months. Very dangerous RX! Start at smallest dose possible - my Doctor gave me ok to break in half even though pills are not scored. Recommend Philips Fiber gummies only & beware of stool softeners, if miss-managed they can lead to impaction So always take pills with plenty of water - plain water! After a year of use, I started to have periods of very high blood pressure, irregular heart beat, abdominal pressure / tightness stomach muscle spasms so severe I was taken to ER - where - after staring at me like I was on a bad drug trip - hooked me up to IV which only made things much worse. Later, after some yelling... a bright nurse injected me with Ativan. Not sure why but with-in 5 minutes everything subsided. I felt completely normal, maybe a little sleepy. The docs. Said well we got nothing so you might as well go home then see regular Doctor. Turns out Movantik is very dangerous! Use at your own risk."

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  • Kival...
  • March 20, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Taking it for three months and no bowel movements. I have one movement a month. I really need to poop . All this medicine does is make me felt sick.I take as it says and nothing happens .In between I take Mira lax still nothing. I get nausea vomiting alot of the time.Cramps I am so tired of being full of bowel. ."

1 / 10
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  • WillDoo
  • August 23, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I have Fibromyalgia, IBS-C, & worst of all, OIC. I took as prescribed one day.I got horrible pain and withdrawal symptoms, Gut gurgled for a couple hours in the morning. Then Zip, Nada, Nothing!! I was out after that. 2nd day too sick. I thought I should give it a 2nd try 2 wks later to make sure as I had high hopes I might get back some of my life. Same again but worse. Kept repeating symptoms at odd times for 4 days so far. I dread reliving withdrawals at bedtime. Docs should know Fibromyalgia is brain related disease so the med is crossing the blood barrier."

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  • Lauren
  • June 14, 2019

Movantik (naloxegol) for Constipation, Drug Induced "So I am on 70 mg of Methadone and have been on it for about 4 years. It is what causes my super horrible constipation. I tried 1 25mg Movantik for the first time yesterday. I took the pill at 1pm on an empty stomach when I got home from the pharmacy within 20 minutes I experienced the WORST stomach pain of my entire life. I immediately ran to the bathroom to try to go and couldn't. I had to go lay down immediately the pain was so intense. This was on and off for about an hour with no luck using the bathroom. Then about 1 hour and a half after taking the pill I was in full blown withdrawal. It was terrible I was crying and in so much pain. I was contemplating going to the hospital but I couldn't even walk and muster up the energy to go. I will NEVER take this medication again and I am very very upset my Dr did not warn me about these side affects. Had I known the risk I would have never even tried it."

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.