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Naloxegol User Reviews & Ratings (Page 2)

Brand names: Movantik

Naloxegol has an average rating of 4.9 out of 10 from a total of 269 reviews on Drugs.com. 37% of reviewers reported a positive experience, while 48% reported a negative experience.

Reviews for Naloxegol

  • Herni...
  • Taken for less than 1 month
  • June 10, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I have been taking opiates for 2 years now, but as soon as I started taking morhpine everything came to a halt. I hadn't had a BM in over 8 days. I took the Movantik, and nothing happened at all the first day. Took another one the next, still nothing. Woke up the next morning, and, yeah I had some cramping and gas pain, but I also emptied my bowels of what seemed to be an entire week's worth of poop. Yes, it hurt, but not because of the drug. It hurt because unfortunately, my movement had hardened and was difficult to pass. However, the relief I felt after all was said and done is amazing. I am having regular-sized, normal movements now. None of the withdrawal symptoms, and none of the extreme discomfort like gas, vomiting, or cramps."

10 / 10
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  • Charm
  • Taken for less than 1 month
  • March 21, 2016

Movantik (naloxegol) for Constipation, Drug Induced "I took Movantik on a Saturday morning and 15 minutes later I started having gas like pain, sharp pain in the upper abdomen and it just moved to my intestines. It felt like contractions so it felt like a stomach spasm. The pain level went from a 5 to a 200 in no time. I remember telling my husband to drive me to ER because I've never felt that before. So sure enough. 3 minutes into our drive I started vomiting violently and the stomach spasms were just 1,000 times worse. I would rather have 3 children in a row than go through that pain. At least I knew after that 3rd baby I would be done. I couldn't stop vomiting. The ER kept thinking I was on it to take me off the painkillers. Nobody understood me I just wanted to die."

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  • Jlynn
  • February 1, 2021

Movantik (naloxegol) for Constipation, Drug Induced "I've been on high dose of methadone 10 years. I have chronic constipation. I started drinking Magnesium citrate every other day & it helps 100%. No pain or anything. Lately I've needed to drink more & more so I went to my doctor who explained that it is really bad to drink magnesium citrate as often as I do so she had me try this movantik 12.5mg. I took it, after 15 minutes I started feeling sick, my entire belly bloated out so much I looked about 7 months pregnant! Then I started violently vomiting. I went to bed, then woke up the next morning still bloated. I took another pill, again on the 3rd day I couldn't take it anymore I was going on 14 days without a decent BM...tiny pebbles here & there & whatever I could get out with a rubber glove wasn't enough! I got myself a bottle of magnesium citrate & drank the whole thing plus lots of water to clean myself out, then attempt movantik again. It did the same thing, Movantik made me sick & constipated worse than ever."

1 / 10
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Frequently asked questions

  • EMSGuy
  • September 24, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I am on opoids for chronic back pain. Used Miralax and Metamucil but was bowel movements irregular and felt like I was emptying out was backing up. Tried 25mg on empty stomach at 3pm yesterday for first time. Started having cramps. Called my doc and added a suppository. Twenty minutes later had massive BM over 30 minutes. None after that. This morning, woke up in withdrawal, cold, nausea, abdominal cramps, horrible pain and feeling lousy. Odd as my last pain med dose was six hours before, and I do not get withdrawals that quickly. My morning pain meds fixed withdrawals but was still in significant pain until 1pm after second pain med dose at 12. Seems to decrease pain reducing effects of opiods."

3 / 10
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  • hunterr
  • Taken for less than 1 month
  • February 6, 2019

Movantik (naloxegol) for Opioid-Induced Constipation "Worst medication I've ever tried. It gets rid of your constipation but also causes horrible withdrawal. At first I thought everything was fine. 6 hrs in I had gone to the toilet 4 times. I was okay except for some stomach pain which I expected. After 8 hrs in I had the most horrendous cramps of my life. My whole body ached. I was nauseous. As time goes on I realized I was in full blown withdrawal. I started shivering. The cramps, pain, and diarrhea were horrible. 12 hours in I can't leave the toilet. My pain's unbearable. I felt I had nothing left to evacuate but I keep just cramping up. My entire body is shaking. FYI I take 30mg oxycodone IR every 3 hrs & Norco 10 4x daily. Movantik has made this ineffective. I'm writing this in the hopes that you DO NOT take this drug. I was going to the bathroom every morning with just miralax. My insurance company decided to stop covering it. But I'll figure out I'll just buy the miralax. Its the next morning now and finally its over except for residual cramps."

1 / 10
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Are you taking this medicine?

  • Emily...
  • Taken for 1 to 6 months
  • October 10, 2017

Movantik (naloxegol) for Opioid-Induced Constipation "I think it’s crazy that medicine specifically prescribed to opioid users will cause opioid withdrawal. Forget that! Take Linzess ! I’ve been on Suboxone for 3 years. I’ve had terrible constipation and when I would finally go, it would be rock solid and extremely painful. Linzess has been life changing. I go everyday. I’m on the highest dosage, the low dosage did absolutely nothing at all. Being constipated is a big deal. It’s awful! My heart goes out to anyone who suffers from it."

1 / 10
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  • Art
  • Taken for 1 to 2 years
  • April 27, 2019

Movantik (naloxegol) for Constipation, Drug Induced "I have been taking Movantik for a year now . At first administration I had some cramping from the stools moving within the intestines . They were a little painful in the beginning but after continuing treatment it is working good for me . I have a bowel movement every morning . I'm on Oxycodone 30mg x 5 a day . Movantik was the only medicine that works compared to all others . I take it as soon as I wake up, an hour later a BM, then I’m good for the day ."

10 / 10
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  • mitch...
  • Taken for 1 to 6 months
  • February 1, 2017

Movantik (naloxegol) for Constipation, Drug Induced "I started taking movantik about 3 to 4 months ago. At first it seemed to work great. Then as weeks went by I noticed that it did not seem to work as well or at all. I started taking the drug in the morning and then late at night and usually the second dose would work. Then I noticed something strange where I would feel really sick especially during the daytime. And I finally figured it out and realized it is the movantik causing withdrawal symptoms. Not like complete withdrawal because I am on Fentanyl patches. But enough of a withdrawal feeling where I can not function at work. My recommendation is to not take this drug more than twice a week because it loses its potency. And only take this drug at night so you don't have withdrawal symptoms"

5 / 10
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  • Brbsch
  • Taken for less than 1 month
  • June 6, 2017

Movantik (naloxegol) for Constipation, Drug Induced "I have a spinal cord injury & have been taking methadone for nerve pain & oxycodone for hip pain, over 15 years. Had been using miralax but not as effective as I would like. Doc recommended movantik, I figured it couldn't hurt to try it. Was I ever wrong. The warnings about methadone users is very accurate. Within 2 hrs I was doubled over in pain, in the bathroom nearly 2 hrs while my body cleared out. To the point of practically urinating from my butt. It was excruciating, cramps, nausea, severe sweating & had a pressure in my head for about 6 hours. I was very ill & out of it. I was extremely afraid, pain was so severe I thought something was wrong, was considering going to the ER but couldn't get off the toilet. I think this med is dangerous."

1 / 10
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  • Jerem...
  • January 3, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Horrible! I've been on methadone maintenance for 2 years and the past 8 months my bowels have stopped. I've used every laxative you can imagine and finally got the courage to see my doctor. He gave me samples of Movantik, I read nothing but bad reviews but desperate for relief I took one 25mg tablet and about 2 hours later it threw me into precipitated withdrawals. Sweats chills and everything else, sad part is I didn't even get a bowel movement. I don't suggest this medicine for anyone it's garbage!"

1 / 10
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  • LH9889
  • Taken for less than 1 month
  • September 8, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I am second day of this medicine and am considering stopping it altogether. I take 100mg of Morphine x2 daily and am currently miserable on Movantik. Whatever comes out of me is pretty much all liquid after it woke me multiple times to go to the bathroom after resting from severe stomach pain. I am now going to the bathroom a minimum of every hour for all 24 hours. I never thought a drug could make me so sick. I am in so much pain and so nauseous. I am going back to Miralax, at least with that I know the minimum side effects on Miralax."

1 / 10
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  • Terry...
  • Taken for less than 1 month
  • November 7, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Within one hour of my first ever does (25 mg), I was in agony. Sure, I pooped but then, I kept on and for hours (total four). In that entire time, I had the most severe intestinal pain I've EVER had! Bent over, screaming, clutching a pillow hard against my gut, I was repeatedly having watery brown smelly feces fill the adult diaper and run down my legs!! Am now in hour four, it's less than it was. Comes in waves. Is there no antidote? No way to make it STOP???? The pain is making me short of breath. My neck and lower back muscles are like tightened ropes. WHEN WILL THIS END???"

1 / 10
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  • Fibro...
  • Taken for less than 1 month
  • July 26, 2020

Movantik (naloxegol) for Opioid-Induced Constipation "This stuff Movantik is a lifesaver. I take Percocet 10-325 twice a day for a blown out disc while I'm waiting for surgery. I'm 45. So, I've been on these opioids for about 1.5 months and the side effects from the opioids is this constipation and resulting anal fissures (blood) are a real problem for me. I had some success with regularity using mini enemas but was still backed up! First day, I took Movantik early in the morning with coffee and had one good BM. Next day, I took it late afternoon and nothing. Next morning, took my third dose first thing (with coffee, before opioids) and within 4 hours had 3 BMs. I'm not crampy at all. Only side effects for me is I feel sweaty and I have to wait until after BMs to take my opioids. Worth it!!!"

9 / 10
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  • Proemed
  • September 20, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I use Movantik as prescribed for what it is prescribed 4 Opiate induced constipation. Every time I take it I get some gas, some pain, but never a BM. This is probably the mostly worthless medication I have ever used... Almost anything else is more effective than this giant placebo. Its expensive. and yet, cheap OTC drugs work SO MUCH BETTER."

2 / 10
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  • PODs
  • Taken for less than 1 month
  • July 15, 2018

Movantik (naloxegol) for Opioid-Induced Constipation "Ok, I have been prescribed opioid pain medication for the past 17 years after I fractured my skull. I have literally been on every pain medication known to man! I was on Duragesic for 3.5 years---400mcg every 3 days. All opioid pain meds cause constipation. I have tried many laxatives, however, NONE of them have worked at all! I saw the commercials for Movantik and asked my Doctor about it. He prescribed the med for me and I started taking it 3 days ago. Movantik works, at least for me. Two hours after taking the dose on the first day, I felt somewhat queasy and slight cramps. Wow! There was no explosion, no diarrhea, no unpleasant side effects. It just worked. I take Movantik in the morning an hour before I eat. Within 2-3 hours I have a bowel movement and that is the extent of the experience. I feel like a new man"

8 / 10
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  • Bob
  • Taken for less than 1 month
  • November 2, 2019

Movantik (naloxegol) for Opioid-Induced Constipation "I've been on methadone maintenance for over four years. And I've been having problems pooping ever since. I heard about movantik a couple days ago so I ask my doc about it and I haven't felt this good in along time other than having the severe diarrhea for the first couple days after taking it, it has been great."

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  • Ranger
  • Taken for less than 1 month
  • September 14, 2018

Movantik (naloxegol) for Opioid-Induced Constipation "I took this drug at 8:30 pm. At 9:15 pm had to go to the bathroom due to H-O-R-R-I-B-L-E stomach cramps. Then it got WORSE!! At 10:30 I had to be taken to the ER and screamed so loud due to the pain my throat is raw. It took 4 shots to get me to stop screaming. I threw up all over the bed and floor. DO NOT take this med. There are so many other alternatives."

1 / 10
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  • Maddog
  • October 14, 2015

Movantik (naloxegol) for Constipation, Drug Induced "The cost of this drug was enough to give me a bowl movement right at the counter $197.00 WITH 75% off. Are the manufactures for real ??? From what I have read above, the % of people this has helped does NOT warrant such a price."

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  • Cakeb...
  • Taken for less than 1 month
  • October 17, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I have chronic pain issues and have for years. I am on oxycoton & oxycodone. I have dealt with drug induced constipation for years. I will NOT ever take another dose of this medicine. It's been several hours since I took my first dose and I was surprised that I had a bowel movement within an hour. Regular which was nice for once, then had to go again right away.. and again.. and again, and things got softer, then went to liquid. I went to bed around 1am and was awoken with an urgency to go to the bathroom only to find that I had "wet" the bed by the bowel leaking while I slept for ONE hour. My bed was soaked, I was soaked. Not only was I humiliated like a child would be, but the diarrhea isn't stopping! From what I read best is yet to come!!"

1 / 10
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  • Jenn...
  • Taken for less than 1 month
  • November 3, 2016

Movantik (naloxegol) for Constipation, Drug Induced "OMG!!!! This is horrible!!! The cramps n bloating are the worst I've ever had!!! I suffer from multiple pain issues, fibromyalgia, severe neck and back pain with shooting pins and needles with burning down my legs. Due to a failed back surgery. I'll take that pain over the pain I have from Movantik. I have been back and fourth from the bathroom and sat on the pot till both of my legs are numb. Nothing's moving but I'm having such bad cramps I can't move."

1 / 10
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  • Nessa
  • Taken for less than 1 month
  • November 25, 2020

Movantik (naloxegol) for Opioid-Induced Constipation "I only weigh 110 pounds. So as a precaution I cut the Movantik in half and I'm glad I did. I did everything else I was supposed to do. It was easy not to eat before I took it by only taking it right after I woke up. That way nothing was in my system. I waited 1 hour to eat and drink coffee. After my coffee I had luck and I was good to go. Yes it made me weak and a little sore feeling in tummy but the extreme sickness most people get on here is not my experience. My menstrual cramps are a bit worse. I only take low dose tramadol. Been on the same amount for 6 years and only the last few months have I felt constipated. I can't believe how long people wait to seek medical treatment. No wonder you people are getting that sick. Also follow the rules and don't eat in that window of before and after."

5 / 10
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  • SubsB...
  • August 15, 2018

Movantik (naloxegol) for Opioid-Induced Constipation "I'm on Subzolv which also causes constipation. Movantik 12.5 once in the morning as needed works great for me. No side effects. I'm sorry to hear these extreme stories and I will begin taking a half dose and see the effects. I will post. Good luck all."

10 / 10
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  • Marci...
  • Taken for less than 1 month
  • October 2, 2016

Movantik (naloxegol) for Constipation, Drug Induced "Awful stomach pain that lasted hours. Very small amount of diarrhea. Not worth the pain. I threw the medication away it was that bad. I didn't want to be tempted to take it again.Its really that bad. I wouldn't even bother halving the 25mg tablet. Also the fact that it seems to suck the options out of your body I'm in more pain that before unfortunately I had taken my morphine before this drug. Stay away from it terrible medication."

1 / 10
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  • Range...
  • Taken for less than 1 month
  • August 23, 2015

Movantik (naloxegol) for Constipation, Drug Induced "I have had constipation for months since taking Pain meds that I need for extreme back pain. The constipation has been so bad that it has made my back pain even worse. My doc gave me movantik and it has truly saved my life. It has regulated me, and made me regular again with hardly any straining. I cannot say enough good things about movantik and how it's been a game changer for me. Amazing!"

10 / 10
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  • Vlynx
  • Taken for less than 1 month
  • September 5, 2015

Movantik (naloxegol) for Constipation, Drug Induced "3 stars because it induced a BM. I had been constipated for a couple weeks, not no BMs but few and incomplete with bloating and discomfort. From reading the literature I thought this might work, after several hours. But, wham! one hour after taking (on an empty stomach to decrease systemic uptake) I had a large BM. Great, but then I got severe intestinal cramps. Thought I was going to perforate something. After a couple hours then watery explosive diarrhea the rest of the day. OK, it cleaned me out, but at the expense of great pain and inconvenience. I'll go back to Senna & Miralax. Perhaps my opioid intake is too high for this? It was tested on people taking morphine equivalents between 30 and 100 mg/day. I take more than that."

3 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.