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Desoxyn User Reviews & Ratings (Page 2)

Desoxyn has an average rating of 9.3 out of 10 from a total of 40 reviews on Drugs.com. 91% of reviewers reported a positive experience, while 4% reported a negative experience.

Reviews for Desoxyn

  • 1337
  • Taken for 1 to 2 years
  • February 27, 2020

"I have Idiopathic Hypersomnia and no stimulant worked for me prior to Desoxyn. I haven’t had to increase my dose (40mg/day) and for the first time I’m not on an off-label dose. I feel calmer on it, it boosts my mood, I have more of an appetite on it (compared to others) and it keeps me awake! The only downside to this medication is how difficult it can be to obtain. My insurance changed and it was a battle to get 40mg approved and it cost more. I’m scared to ever switch again because it’s a constant battle when it comes to insurance. I’ve had to go on many a medical treasure hunt to get it due to the name’s bad reputation. I can start/stop it no problem. I’ve never felt high on it or craved it. It doesn’t make me angry, super irritable or depressed. It’s by far the best I’ve tried for IH!"

10 / 10
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52 Report
  • Anonymous
  • June 22, 2008

For ADHD "I would give it a 10 but will err towards conservative and give a 9; only because it has a high abuse potential and humans are inherently prone to some type of addiction. It has pretty much NO side effects if taken as directed for adult add and after 5 years on it, I feel it has stabilized me more than any others. Adderall is second place for me but it is more likely to make me irritable after therapeutic effects wane for the day. I have taken Desoxyn before and fell asleep!"

9 / 10
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127 Report
  • Fatty...
  • November 17, 2009

For ADHD "Desoxyn has opened doors to my life, heart, and mind that I thought would never be able to be opened and be shared with the world. The side effects were little to none and other medicines side effects greatly outweighed the Desoxyn effects."

10 / 10
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111 Report

Frequently asked questions

  • Bosto...
  • November 5, 2016

For ADHD "I've used all the first line ADHD meds beg. in 2003 and only 1 was effective but of course my tolerance is depleted it's not so effective now: Adderall generic 30XRAM,0 regular PM. Yet, without it I'm like a hyperactive confused kid again. I don't want a higher dosage.I want a change- I asked my older,psychiatrist (been with him since late1980's ) about Desoxyn which he said "I've never heard of it". He's 100% Psychopharm. treats kids thru seniors; MA trained MD, Harvard+ BU Med School,is it possible that MA laws never permitted this medication tb used 4 ADHD ? Should I ask again or won't find it in MA pharmacies? Don't want to sound like a druggie either but it's frustrating to be stymied. At my age,62.5, I'd like some relief again"

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67 Report
  • huang...
  • February 11, 2019

"I had have try all the stimulants, but all of them give me bad side effects except with Desoxyn. It is the best med for me and I do not crash like others that I need to take a nap to feel good ! Desoxyn is not that type of bad illigal drug-that is not true... It did get my fatigue away 99% and I stop feeling weak and nerve pain and depression went away to. If you sensitive like me to medicines this one is the right for you! I hate that the insurances do not want to cover it, I dunno why but I did use a coupon ended up paying $113. I hope you fund this helpfull!"

10 / 10
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41 Report

Are you taking this medicine?

  • ngquinn
  • July 24, 2018

For Weight Loss (Obesity/Overweight) "Back in 1971, I got prescribed "Desoxyn", for obesity. I was 28 and weighed way too much to be healthy. I lost 55 pounds in 11 weeks, on Desoxyn, so I kinda swear by it. I've taken more than prescribed on a couple occasions (accidentally) and do NOT recommend this as the side effects were not good for me. I completely understand why this stuff is controlled. I moved away from my Doc and pretty much took myself off it"

10 / 10
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44 Report
  • Chesh...
  • Taken for 2 to 5 years
  • February 4, 2022

For ADHD "Desoxyn was the greatest treatment for my ADHD I have ever received. Alas, I lost access to my prescribing doc and thus his scripts several years back over a national shakeup in health insurance. Naturally, some should never be prescribed this drug (it's methamphetamine after all). Abusers aside, however, if one struggles significantly with ADHD, Desoxyn may be the key when all else falls short. It certainly was for me. At the time of my Rx, I was completing graduate courses, all of which I aced. I also received flawless scores on two different research papers. I was dosed at the advised max 25mg/day; and while I could sense the stimulant working, I wasn't beset by dependence, and it never triggered euphoria or entice me to abuse it in any way. Given the stigma that surrounds Desoxyn; and with insurance getting ever more selective over drug coverage, I regret not expecting to reap Desoxyn's benefits again. But I'm thankful for the remarkable blessing it was while it lasted."

10 / 10
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19 Report
  • Hope...
  • Taken for 1 to 6 months
  • December 10, 2021

For ADHD "24-year-old male here. Wish I could explain my full 6-year story and share advice and words of support, but there’s a char limit. My experience: 1. Adderall didn’t work, caused anxiety at higher doses (IR & XR) 2. Concerta 36mg helped a little. 54mg genuinely worked… for the first 2 days 3. Focalin lived up to its claims. More tolerable & effective. I still couldn’t work like a normal person 4. “Final showdown” time. Requested a month of Desoxyn, then a month of Dexedrine 5. Lots of experimenting (within FDA guidelines). I found them to be the 2 most effective, with Desoxyn winning. (Um… no idea why 3:1 AMP salts combo did nothing.) It’s neither magical nor scary. I’d say #1 for efficacy, #2 for tolerability (2nd to Focalin). Feels similar overall to other ADHD meds. Only anomaly was mild euphoria the first 2 days. Less addictive than coffee. Only “big W” could order it. Even on this, I still struggle. But it’s the best I’ve got."

8 / 10
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  • Alex
  • Taken for 10 years or more
  • June 21, 2023

For ADHD "Like all the other reviewers, I have tried all the other "modern" ADD stimulants. The common theme of all other reviewers is that these medications all leave the user feeling "jittery" or "tweaked" This is my experience as well. I can only describe the stimulative effect as so very much "cleaner." It is an entirely superior experience in every manner. There are only two disadvantages. 1. Its base chemical name is of methamphetamine; as soon as you bring this up to your prescriber, they will immediately suspect you are a meth head trying to get high legally and will be highly suspicious of you and resistant to prescribe it for you. Due to the drug schedule levels, it must be specially ordered for you. Additionally, it is unavailable in higher strength tablets, only in very small 5 mg. Effective therapeutic levels call for a dosage of 30 - 60 mg twice daily. I guarantee your doctor is going to be very resistant to prescribing you 6-12 pills 2x daily"

10 / 10
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  • Publi...
  • Taken for 1 to 6 months
  • April 7, 2023

For ADHD "Prescribed Desoxyn for ADHD, initially 5mg/day up to 20mg/day. It helped a bit with focus and motivation, but it caused profound discomfort, e.g. increased anxiety, a rapid heart rate that was distressing, dry mouth. I don't know why people rave about Desoxyn. I think it's because it's methamphetamine so they think it has to be good. Since it's the most potent stimulant it has to be the most effective. That logic is flawed. Desoxyn has a very narrow therapeutic index. It can cause neurotoxicity at slightly higher than usual doses, and the long-term effects on the brain are unknown. I would stick to the amphetamine salts, such as Adderall. It never made me feel edgy and uneasy, in fact it was "gentle" and just worked. It didn't cost an arm and a leg. Desoxyn only comes in 5mg tablets. The usual dose is 20mg-25mg a day. It ended up costing me about $670/mo. Insurance rarely pays for it. Maybe there's a tiny group for which Desoxyn is appropriate. But I have a lasting aversion to it."

3 / 10
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10 Report
  • Rx2009
  • October 27, 2009

For ADHD "I took the tablets after being on all forms of Dexedrine, Ritalin, Adderral, etc. It had no side effects, but was not as big a deal as it is made out to be. Dextroamphetamine spansules (brand SKF) are far more effective and long-lasting for ADHD, which I've dealt with."

7 / 10
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  • Bober...
  • Taken for 2 to 5 years
  • November 9, 2023

For ADHD "I've got several gene variants that make the usual stimulants (regular amphetamines like Adderall or Vyvanse, methylphenidate like Ritalin or Concerta) not work very well. With the usual stimulants, I need to take large doses (combination of extended and instant release throughout the day), they wear off quickly, and work fairly poorly and inconsistently. Regular amphetamines completely stop working after a week, even at large doses. Desoxyn (methamphetamine) works extremely well, works all day (7.5mg instant release dose 2x daily), works consistently without having to take breaks, and helps where the usual stimulants fail. Most notably, it helps very well increasing my working memory to normal levels (or at least what I imagine that would be). Despite the stigma surrounding methamphetamine, it feels way less stimulating than even methylphenidate does. Unfortunately, it has been unavailable for the past year, with no return apparently on the horizon... :("

10 / 10
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  • Yuki
  • Taken for 1 to 6 months
  • January 2, 2022

For ADHD "I don't get all the hype for this drug. I took Desoxyn for a few weeks but never really noticed much of an effect, other than maybe a little help for focusing on personal projects. I am diagnosed with inattentive ADHD but maybe this drug works better for people with the combined or hyperactive types. It made my stomach feel weird but didn't have any other major side effects. Definitely not worth the ridiculous price tag. Hard pass."

2 / 10
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  • Rachel
  • Taken for 10 years or more
  • May 30, 2023

"I was prescribed Desoxyn in 1992 along with Dexedrine for my narcolepsy. The dose is high but these two medications changed my entire life. I had my first diagnosis, when I was 8 years old, I am now 78. I had started back to college for liberal arts, concentration and alertness were a necessity, since I was working with power tools. These two medications made life new and exciting. I could do everything I wanted, without falling asleep. Now I take Adderall and life is nothing but existing for me. Nothing else works. Now I can't get my insurance to pay for it. It is the only one that works for me."

10 / 10
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6 Report
  • Beach...
  • Taken for 10 years or more
  • November 20, 2021

"When I took Desoxyn when my Dr. suspected I had Narcolepsy years and years ago,(They didn't have sleep studies then) Those were the best years of my life as far as no sleep spells, had a little more energy, was able to focus , was more dependable and happy. That Doctor retired an has since passed and for the last 10 years I've been taking Modafinil and Concerta. NO way near Desoxyn. I feel like I'm in a trance all the time , takes hours to kick in , I'm up at night and in a fog all day or sleeping. Desoxyn was not nearly as expensive either and it ruled!!! God Bless Abbott Laboratories for giving me those years."

10 / 10
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  • Owner...
  • December 24, 2022

For Weight Loss (Obesity/Overweight) "Works great. Losing weight. I had to cut to a lower dosage in the beginning due to side effects: breathing issues, chest discomfort, and headaches. But once I lowered the dose it worked great and I started noticing weight loss shortly after I started taking the supplement/medication."

10 / 10
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  • LifeS...
  • Taken for less than 1 month
  • October 22, 2023

"Long story short. Autism, severe sensory processing issues, frequent bad self-injurious meltdowns. Unmedicated ADHD. On over 10mg Xanax daily for over 3 years. Memory gaps and poor relief from sensory overload, but fewer meltdowns. I'd still have breakthrough meltdowns, and it lowered the quality of my life. Got off it. Started Desoxyn a few days ago. Was scared to take my first dose because stimulants have always made me immediately go into intense sensory overload. This was prescribed as a last resort for ADHD and BED. My first dose was taken as I was about to enter a bad meltdown and totally lose control. My friend made me take my first dose when I started to yell at barking dogs from the street. Within 15 minutes, the sensory overload was completely gone. I feel able to focus, but without the horrible side effects of literally every other stimulant I've taken. Desoxyn saved my life and has finally given me back power over my life, future, and brain."

10 / 10
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2 Report
  • mark
  • November 17, 2015

For ADHD "10/10 miracle for my ADD, fog/fatigue, OCD. Can now take things 1 at a time. No more racing thoughts! Minimal side effects. Thank you for helping!!!"

10 / 10
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115 Report
  • Tried...
  • March 10, 2008

For ADHD "The cadilac of ADD medications! Little to no side effects. Only one that truly helped me."

10 / 10
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160 Report
  • Anonymous
  • June 8, 2011

For Weight Loss (Obesity/Overweight) "For short term treatment of obesity there is no doubt this is hands down the best thing on the market. "

10 / 10
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119 Report
  • Anonymous
  • November 23, 2009

For Weight Loss (Obesity/Overweight) "The best drug out there for weight loss, and it gives you a boost to get things done."

10 / 10
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125 Report
  • Anonymous
  • December 6, 2011

For ADHD "Works very good as a stimulant in the treatment. It also helps in calming the brain. Storm of thoughts without the hyperfocus that other stimulants seem to bring on."

7 / 10
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104 Report
  • Nobody
  • July 26, 2022

For ADHD "This is the only stimulant that works. No increased heart rate, no increased blood pressure, no anxiety. It just works. It actually helps me sleep."

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17 Report
  • Descon
  • March 3, 2024

For ADHD "Desoxyn could be a lifesaver. I like this medicine very much. It is very good to use it carefully and under a doctor's supervision. I am glad I know this medicine."

10 / 10
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2 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.