The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Compare all 99 medications used in the treatment of Depression.
Reviews for Cymbalta to treat Depression
Review by Danny in Green Bay:
First of all, I was prescribed to Cymbalta/Buspar at the same time to treat my depression/anxiety, respectively, and I can say that I experienced absolutely no side effects from the Cymbalta and I seem to "care" slightly more about other people not just myself. I've been taking Cymbalta for 4 weeks now and am unsure if I've experienced the full effect of what it should be doing for me
I have been using Cymbalta for the last 5 years I started at 30 for a month, then 60 mgr and finally 120mg because I was under treatment for Severe Post-Traumatic Stress Disorder where initially I started with Efexor XR 250mg very bad medicine for people with high blood pressure (made me sweat like crazy and I have up\down mood issues and increased the feeling of hunger).
Then the doctor put on Paxil.. even worse
During last year I tried to leave Cymbalta for good, but it did not work, I started feeling very anxious, upset, very depressed and electrical shocks feeling in my head nausea... I went back to my doctor and from 30 mg I went back to 60mg.
This medicine worked well for first 5 months, but has since stopped working. I have also put on 20 lbs in the past 4 months and I am very tired . I am about to go off of the medication, but I am very nervous about side effects.
For anyone suffering from depression I cannot tell you how much this medication has changed my life. I had been suffering with depression and anxiety for years, severe depression started a year ago when I lost my father, I had
Been taking Zoloft 100 mg for about 5 years, worked great for the anxiety but did nothing for my depression. My doctor added Wellbutrin 100 mg to my Zoloft, the Wellbutrin was awful, gave me kind of an agitated energy and no help with the depression. I'm on day 3 with Cymbalta, weaning off Zoloft, so 50mg Zoloft a day with 30 mg Cymbalta. Before I started taking Cymbalta I was to the point of just wanting to go to sleep and never wake up. Cymbalta has given me back my life! I only wish I had known about it
22 users found this comment helpful.
I have been taking Cymbalta for depression and have been on it for almost a month. I have noticed a change in my mood. I am starting to feel better about everything. I don't feel like I'm walking around in a fog anymore. I felt really tired for the first couple of days and mostly slept, but now I'm feeling much better. I haven't felt any other side effects. I have taken other medications for depression, Paxil, Celexa and Effexor. Paxil and Effexor didn't work for me at all and the Celexa worked for about a year and then, didn't work at all. I hope that Cymbalta will keep working for me, because I don't want to change medicines again. Cymbalta is working for me already and I hope things will become even better the longer I'm taking it.
13 users found this comment helpful.
I started taking Cymbalta after my doctor prescribed 2 other medicines over the space of 8 months, they made me feel worse not better. I was so ill I was hospitalised at one stage. It took Cymbalta quite a while- about 2 months, to kick in noticably, however my depression was severe. The nausea was awful the first two weeks and dizziness lasted about a week with me. I am pretty sensitive to medications however. I have been on Cymbalta for almost two years- at a high dose (90mgs). I do find I am hot and sweaty (at times), I need a lot of sleep and have put on weight, (though HRT could have caused this). However these side-effects are a small price to pay to live a normal life and be free.
12 users found this comment helpful.
It really helped me and did wonders on my depression that I've dealt with since high school and I am now 26 years old and it also helped with my panic attacks. However the side effects for me are I have put on 35 lbs in less than two years and I am extremely fatigue almost 24/7 and get irritated easily. Actually going back to the doctor next month and my husband told me to suggest something else and as much as it does help of course the weight gain and irritation sucks.
Cymbalta is a miracle. Prescribed for depression and anxiety and saw results within 24 hours (yes, unusual). A smile was glued to my face the next day with colleagues asking why I was so happy. Side effects were mild and disappeared quickly. Been on for 6 months now. My lower back pain is gone (suffered for 14 months while seeing doctors) and my PMS symptoms and cramps are non-existent. I used to cry at the drop of the hat, bite the head off of my husband, and get easily irritated and agitated at everyone and everything. My husband claims that I've never been nicer. I thank my doctor for having the foresight to suggest it to me.
31 users found this comment helpful.
I have been on Cymbalta for 4 months. I have had a multitude of side-effects with this medication including irritability, moodiness, respiratory problems, gastrointestinal bleeding (just to name a few).
I suffer from major depression and was placed on Cymbalta 6 yrs ago. I took myself off against my doctor's advice. Life became hopeless and all I though about was wanting to die. Now I've been back on it for 18 days and I'm on top of the world. The future looks bright and I'm certainly enjoying the present!
23 users found this comment helpful.
Cymbalta works very well for me. I was very reluctant to try it because of the concerns other users have brought up re: side effects and horrors of withdrawal symptoms and talk of "brain zaps." I started Cymbalta after trials of Wellbutrin, Lexepro and Celexa within the last two years. I was desperate to relieve my depression. I began Cymbalta in the spring of 2011. One side effect I occasionally suffer is stomach upset/burning. Tums relieves the symptoms as well as omeprazole. The other side effect I occasionally suffer from is the flu like symptoms (withdrawal symptoms) if I forget a dose or am late with a dose. I found the best time to take Cymbalta, for me, is at noon.
Cymbalta was the worst possible medicine I have ever been on. Not only did it not help my depression at all, it actually made it worse. I also started taking it for Fibromyalgia pain which it did not help. Indeed, I have had more pain since starting on the Cymbalta than before I was on it. I can't even count how many times I have considered putting myself in the mental health ward of the local hospital.
10 users found this comment helpful.
I am scared of antidepressants as I had a bad occurrence weaning off Zoloft 10 years ago. I moved across country and back in 2 months time lock, stock and barrel. My new doctor has placed me on Cymbalta. I started on Nov. 16, so it's been 3 weeks and 1 day. The first 4 days were the hardest; however, I have felt more calm and at peace. I only want to be on it to get me through the rough patch. Once I have a routine again (job) I will (under a doctor's care) wean off slowly. I was told weaning off Zoloft should have been done in a year's time, not 3 months as I thought would work. I learned a very hard lesson. My advice, don't wean off any of these medicines on your own. It was extremely costly for me and difficult.
After taking Cymbalta for 3 weeks I become gradually more nervous, by 4 and 1/2 weeks I felt like I was having a constant panic attack. I felt terrified all the time but I couldn't even tell you what I was terrified of. It was the most horrible feeling I've ever experienced. My doctor insisted that I increase the dose but I refused. I finally argued with him and demanded to be taken off. I've been looking for someone else that experienced a similar reaction.
10 users found this comment helpful.
I've been on Cymbalta for depression and GAD since July. I don't think it is working. I am still depressed and have anxiety attacks several times a week. Have talked to my Psychiatrist about this and he just says to give it more time. I am changing Psychiatrists after the first of the year.
I was on Cymbalta about a year ago but when I found a job I wasn't able to make my monthly appointments due to being new and have a probationary period, so I stopped cold turkey and stayed very very dizzy but I was able to beat it and the dizziness went away. After losing my job my depression worsened very bad so I went back to my psychiatrist and got back on them. I got so bad I cried a lot while being alone, suicide thoughts, anger and hatred, lack of confidence. I sat in a recliner for 16 to 18 hours a day, but let me tell you something when I got back on Cymbalta 60mg I have done a complete turnaround. I have lost 40lbs, sex life is great now, my confidence is through the roof. I smile and laugh instead of crying, no suicidal thoughts.
34 users found this comment helpful.
I have suffered from major depression since childhood and have had fibromyalgia since 2000. I've tried Effexor, Paxil, Elavil, Zoloft, Lexapro, Wellbutrin, Nortriptyline, Prozac and on and on. All made my depression worse and left me so tired I couldn't function. I promised her that I wouldn't quit taking it because of side effects and without talking to her first. Three weeks I had had it but my husband kept encouraging me and my doctor was out of town. 5th week all the side effects (super, super fatigue, dizziness, nausea, stomach cramps, yawning, no appetite) have disappeared and I feel fabulous emotionally and physically. Give it time if you've had little success with other antidepressants. This one worked for me.
25 users found this comment helpful.
I have been on Cymbalta for about 7 months so far right and will continue to be on as instructed by my doctor. I am one of the luckiest who had no insomnia nor stomach problems because of it. I had bipolar and Cymbalta started to make me get better in its second week. The first week was slightly difficult, I had some cold hands and swinging mood struggles but they were pretty tolerable and went away fast. It's easy to focus on sports activities with it and it doesn't affect your nerve /muscle system badly. The withdrawal should be very carefully handled though because even when I forgot to take my pill one day, the next day I started having stomach and attention problems, low blood pressure and fatigue.
Have had major life changes the last two years and been depressed and weepy most days. Doctor prescribed Cymbalta 30 mg. On day 3. My head feels foggy and am tired all the time. I keep waking up at night but fall back to sleep.
After my mum's death my doctor put me on this and it was a life saver. I took largest dose 120 mg. It helped me deal with her death and not stay in bed. I also found my arthritis from previous yrs never bothered me anymore. Body aches gone. I did wean myself off medicine after almost 3 yrs. But all body aches and pains came back. I am looking in to Going back on it for body aches.
For anyone taking this or planning on taking this, DO NOT DISCONTINUE WITHOUT WEANING OFF!
That said, besides brain zap, yawning and anorgasmia over the first 3 months of treatment (18 months and counting ), Cymbalta has been a great treatment for my anxiety / depression issues. I have only experienced these side effects when changing dose or missing a dose (30mg a day, last 15 months, 60mg a day for first 3). At one point I wanted to come off it, GP guided me through a 12 week taper off course, but my 2-5 drinks a month were causing the problems I had associated with the medicine. I no longer drink, and it's all so cruisy.
I take mine 1-2 hours before 'bed time'. Works for me because I tend to sleep deeper and wake with lots of energy.
Went on 60mg Cymbalta. Was amazingly good for about a year. Minimal side effects except for some reduction in appetite which was a bit of a problem and causing tiredness at work. It got my life back for me for a while at a time when I thought only of death. I began socializing and getting into hobbies, etc. I then had to work on issues I had created while in depression such as drinking. At about 1 year however some strange effects started occurring. I would for about a week per month become fearful and could not leave the house. Eventually went to a psychiatrist who suggested stopping cold turkey. That was okay, no problems.
Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment.
Data sources include Micromedex™ (updated Dec 30th, 2013), Cerner Multum™ (updated Jan 17th, 2014), Wolters Kluwer™ (updated Mar 2nd, 2014) and others. To view content sources and attributions, refer to our editorial policy.