User Reviews for Cymbalta
The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Learn more about Cymbalta.
Reviews for Cymbalta to treat Depression
Review by NoLongerDown:
Amazing! Best depression & anxiety medication I have been on & I have tried many. Horrible initial side effects but after 2 weeks subsided. Without a doubt completely worth it. Anxiety & depression dramatically diminished, libido back with a vengeance :) HIGHLY recommended from a person with a long history of acute anxiety & depression which was made worse by not being able to find a suitable medication until now. Best 6 months ever.
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April 25, 2015 5:58 PM
Review by lesweet1971 (taken for 5 to 10 years):
I would have rated Cymbalta a 10 if not for lowered libido & difficulty going off of it (not uncommon for most all AD's). I took for 6 years after an episode of anxiety & depression. I would still be taking it but it effect was dropping off after about 6 years so I switched meds (wish I hadn't have messed with switching but that's another story). The only side effect I noticed consistently over 6 years was decreased libido. I'm sure there were initial start up effects but I was such a nervous wreck that I either didn't notice or don't remember. It was a great med for me & I wish it still worked.
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April 10, 2015 10:28 PM
Review by StormyRed48 (taken for 2 to 5 years):
Works really well with little or no side effects.
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April 7, 2015 12:15 PM
Review by Tayaloxely:
I have been on SSRI since the age of 14 now I can tell you I am 42 now and have lived half my life in a fog. Feeling tierd, not interested in anything just wanting to sleep. I changed from lexapro to cymbalta a week ago and wow. I have energy I'm not like dragging myself around all day. I feel motivated - the only down fall has been hot flashes. I read cymbalta can cause that but I will deal with it as I feel as great. I have more than one emotion, I would say definately try it everyone is going to respond differently. Have had some issues waking up alot at night. But that's about it. I have to pay 200 dollars a month for this medicine but it is worth it. Good luck to you
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April 6, 2015 7:07 PM
Review by Beware of Gods (taken for 2 to 5 years):
I had been suffering with chronic pain for years. Finally, a friend pointed out to me how depressed I was most of the time. I suppose I have been suffering from some sort of depression most of my life, but just accepted the feelings as normal or just my personality in general. Finally I found a pain specialist who put me on a very effective combination of meds, including Cymbalta. Along with morphine and percocet it has worked wonders for me. I seem to be as good now as I could ever imagine. Bouts of depression are very mild and far between each other. My pain is still there but mild enough to not effect my outlook on life. The only warning I have about taking Cymbalta is to make sure you don't run out. Missing few days is a horror
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March 22, 2015 10:00 PM
Review by Anonymous (taken for 5 to 10 years):
Been very helpful
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March 16, 2015 2:27 PM
Review by bry188uk (taken for 5 to 10 years):
I took this medicine for about 5 years in addition to Lithium for bipolar 2. It was good for depression and anxiety, but I found I was tired a lot, and if I got a bad nights sleep (which was often) my mood could drop or I could become slightly hypomanic.
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March 5, 2015 6:56 AM
Review by Esther-essie:
Confusion, grumpiness, memory loss, and lethargy.
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February 24, 2015 3:06 PM
Review by Lukins:
Loved this medication when I first started taking it. I started taking to get through depression and my Father was dying of cancer. Thought it was the best medicine ever until I gained 50lbs within 5 months and the effect of the medication started to wear off. What was worse was the effects of getting off this medicine, vertigo for a month with migraine headache and what I call brain buzz for a month straight, that was tough perhaps worse than having depression. I wouldn't have taken it had I read the reviews first.
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February 11, 2015 10:40 PM
Review by PTSD Paul (taken for 2 to 5 years):
After following multiple combat tours I damaged my rotator cuff on my last tour and was exposed to close impact of mortar/ rocket impacts. Upon my return home, I was diagnosed with minor bruising on my brain, &torn rotator cuff. Later tests found pulmonary embolisms requiring u hospitalization & lead to a botched lumbar surgery & lumbar fusion failure. Leaving me in constant pain. The pain aggregated PTSD, after trying multiple depression meds, Cymbalta 60mg twice a day helped control the depression. However, chronic pain still required pain meds. Prior to the Cymbalta, my depression continued even with pain medications. Once adding Cymbalta (after taking it for weeks), my depression was manageable. Diazepam as needed helps w/ panic attack
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February 4, 2015 2:37 AM
Review by Candy567:
Very helpful but over last year or so waining effectivness.
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January 21, 2015 4:02 PM
Review by Brandy Lee Mahoney2:
I've tried many antidepressants, Effexor XR worked best for me but after complaining about back pain my doctor switched me to Cymbalta. 30mg the first week and then 60 mg. What a personality change in me. I was so aggravated all the time, very snappy. Just not myself. No energy NOTHING however this medicine did work for my back pain. I am being weaned off.
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January 16, 2015 4:54 AM
Review by Pasker (taken for less than 1 month):
I am one of the luckiest one for sure. Cymbalta is only my second prescription after Mirtazapine and it did the magic for me. I love Cymbalta because it not only reduced depression but anxiety too. So its two in one. My depression has reduced a lot in just one week of use. To be honest this medication affected me after the second day of use. And its only a start, I haven't even completed 3 weeks yet. I have full hope on Cymbalta that it will make me a happy person soon. Highly recommended for people who got both depression and anxiety. Side effects are slightly annoying though. It kills my appetite which is really bad for me as I am too underweight, mild nausea in the morning, constipation and top of that insomnia. But it all worth the result.
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January 12, 2015 4:35 AM
Review by cao985:
A life saver. Stopped working after 5 months but I am fascinated how this medicine got me out of severe depression. I was praying to die every night even I am an agnostic. I was that desperate. I don't now it's still beneficial but I take 60 mg just to be cautious. I was up to 120 mg. With Cymbalta now I'm on 54 mg Concerta (wish to take Adderall but not legitimate in my country), 200 mg Lamictal and 5 mg Xanax(built up tolerance) if need be. Still in depression but not bad as the past years. If you have major depression at least give this medicine a chance.
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December 23, 2014 9:51 AM
Review by Nora312:
I've suffered from anxiety and depression for years...my attitude was bad, my outlook on life was bleak, I stressed about everything and I worried constantly. I've tried several different meds like Effexor, Wellbutrin, and Citalopram but those made me feel weird and paranoid and then my anxiety increased. I almost gave up on trying to cure this mess of depression and anxiety I have but after I started on Cymbalta 3 days ago I immediately felt great! I feel so much more alive! The first day I took it I ran to the toilet and vomited but right afterward I started to feel amazing! Now I'm on day 3 and haven't experienced any nausea or vomiting at all. I had sex with my boyfriend yesterday and I climaxed as usual. Cymbalta is GREAT!
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December 22, 2014 7:31 PM
Review by KEB42 (taken for 5 to 10 years):
I got on Cymbalta for depression/anxiety that I had been dealing with for almost 10 years. Cymbalta helped me get myself back and feel great again. Recently, I weaned from the 60 to the 30. I noticed I was feeling very tired (despite 9 hours of sleep) and unfocused at work with low energy. Once I changed to the 30 I noticed a HUGE difference. After 5 years on Cymbalta I am weaning off the medication. Going from the 60 to 30mg was a nice transition and I am confident about weaning off it completely. Everyone has a different experience with the medicine and how it will affect them getting of it. I am glad I took this medication. It saved my life.
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December 4, 2014 8:40 AM
Review by MRSDJMCW (taken for 5 to 10 years):
Have been on a cocktail of Prozac, Wellbutrin, and Cymbalta for several years for both depression, anxiety, and chronic back pain with GREAT success. Just recently I started to notice I was becoming very short tempered, easily aggravated, and irritable. My Psych gave me .5 mg of Ativan, but also decided to wean me off my Cymbalta 60 mg. The Ativan helped me immensely. Unfortunately,within 2 weeks without my Cymbalta my depression returned, I was sleeping all the time, and worst of all I felt like I could eat everything in the kitchen and still be hungry! Gained weight so quickly,and had no ambition whatsoever. I am now on my 3rd week back on Cymbalta and feeling almost back to normal thankfully! When you find what works for you, stick with it!
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November 3, 2014 7:31 PM
Review by realsis (taken for 1 to 6 months):
I've tried about 15 to 20 different antidepressants in the last 21 years. Nothing has really helped, or it would help for awhile then stop working. Cymbalta is only the second medication that is not only a SSRI but works with the dopamine in your body, that I've tried. First was Pristiq and that affected me so badly I wouldn't shower for a week. I didn't want to do anything. Now with the Cymbalta I'm more energetic and less hungry and feel much better! So far it's working out wonderfully.
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November 3, 2014 5:11 PM
Review by Anonymous:
I was on this medication earlier this year and had to stop it because of cost and insurance. I have since been approved for medical assistance and my doctor has once again prescribed cymbalta for my anxiety and depression. I had no side effects like I did with just about every other antidepressant under the sun. This has saved my life.
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October 28, 2014 9:46 PM
Review by Johnnie3 (taken for 1 to 6 months):
Tried most antidepressants, and I was ready to give up. I was tired of trying antidepressants, getting sick while I waited for the positives, only to find out it didn't really help. I've tried Prozac, Paxil (good but stopped working for me), Zoloft (allergic to it), Effexor, Citalopram (worst of all). I don't know what made me ask my doctor for Cymbalta, but I did. It started working the second day I took it! I have been slowly recovering from depression and getting my life back. I hope the same for the people who read this. Never give up hope!
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October 6, 2014 4:32 PM
Review by wfelici (taken for 2 to 5 years):
EXCELLENT results. Effexor became non-effective after many years of use and another life impacting event. Was recently severely depressed and suicidal for about 2 years. Found Cymbalta 2 years ago and it CHANGED MY LIFE FOR THE BETTER. I think this medication is FANTASTIC. I have been diagnosed with major depressive disorder and general anxiety disorder (dual diagnosed) This condition has been with me for many years (runs in the family i.e. mother was severely depressed). Cymbalta 120mg per day snapped me out of it. Under doctor's orders I discontinued current SSRI at the time and started right up with Cymbalta 120mg/day. Within 7-10 days I was out of my depressed state. It has to be the norepinephrine aspect that made the difference.
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September 29, 2014 2:02 PM
Review by mommagedden6 (taken for 1 to 6 months):
I started taking Cymbalta about one month ago. Initially the dose was 30mg for 2 weeks and 60mg following. I cannot believe how well this has helped me. I suffered with depression and severe anxiety. I will continue this medication as I understand full benefit may not be reached for several months. Overall I am extremely satisfied with Cymbalta. My only side effects are constipation and decreased appetite which I have resolved with Miralax and eating small meals more often. I also realized the increased taste of salt during my meals which has seemed to decrease more each day.
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July 14, 2014 6:14 AM
Review by annalee66 (taken for less than 1 month):
I'm suffering from Depression, Borderline Personality Disorder, OCD and PSTD. With the exception of feeling a little sick after taking it, Cymbalta had helped me after only a few days. I've tried Effexor, Zoloft, Paxil, Pristique, Prozac, Ciraplex, Seroquel, Trazodone, Amitriptyline and a few more I cant remember the names. I think everyone responds different to medications and all you can do is keep trying and not give up. My mental illness has had a negative impact on my life and ruined many personal relationships too. I have never had any medication work this fast or so well before.
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June 16, 2014 12:25 AM
Review by OLou (taken for 6 months to 1 year):
I took this for depression and chronic back pain. This was an extreme appetite suppressant for me. It worked somewhat for depression, but nothing fabulous. It mostly made me very, very sleepy and physically exhausted.
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May 3, 2014 4:04 PM
Review by Much better now:
I had mild anxiety and intermittent depression. I always pushed through and never thought of medicines. My girlfriend suggested I speak to a psych and I started Cymbalta. In 10 days I had no more intrusive thoughts talking me down, making me stressed, guilty. After 9 weeks, I'm a new man. Small things don't worry me, I am patient and calm driving, I don't wake up for toilet then stay awake worrying, my relationship is closer, I'm nicer to be with. Cons? My libido decreased and climax is harder to achieve (but more intense). The medicine felt strange (out-of-body) at first but I got used to that. I drink more water, I yawn in the afternoons, I grind my jaw a bit, get breathless, mild headaches some days. But my life is much better with this medicine.
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April 30, 2014 1:56 AM
Learn more about Depression
Micromedex® Care Notes:
- Depression After Spinal Cord Injury
- Depression In Children, Ambulatory Care
- Depression, Ambulatory Care
Related encyclopedia articles:
- Adjustment disorder
- Aging changes in sleep
- Chemical dependence - resources
- Depression - older adults
- Depression - overview
- Depression - resources
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- Major depression
- Seasonal affective disorder
- Stress management
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