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Divalproex sodium for Migraine Prevention User Reviews (Page 3)

Brand names: Depakote, Depakote ER, Depakote Sprinkles

Divalproex sodium has an average rating of 6.5 out of 10 from a total of 77 reviews for the treatment of Migraine Prevention. 55% of reviewers reported a positive experience, while 25% reported a negative experience.

Reviews for Divalproex sodium

  • Adam...
  • Taken for 1 to 6 months
  • September 4, 2017

"I've been getting migraines since I hit 30 and they just kept getting worse each year. My neurologist had my on several drugs that seemed to work for a time before they stopped working. Finally I was put on Depakote 2 months ago and it's been fantastic! In just over 8 weeks I've only had a single migraine when normally I'd have 3-5 a week and so far I don't seem to be suffering from any side effects. I can finally work and have an actual social life again!"

10 / 10
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  • dLynR...
  • Taken for 1 to 6 months
  • March 26, 2017

Depakote (divalproex sodium) "I meet with a neurologist for my migraines. He put me on depakote at bedtime. I've been on it almost 6 months now and I am starting to have them as frequent as I used to...3 times a week. I also take Keppra and duloxetine every morning. I've been struggling for almost 20 years now. I just can't get rid of one all the way. Any hospital visit that I go to, they give me benadryl and tramadol, even when I tell them it doesn't work for me. I've only gone to the hospital about 6 times in my life for them."

2 / 10
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  • Shelly
  • Taken for 1 to 6 months
  • March 26, 2018

Depakote ER (divalproex sodium) "I've been on depakote ER once at bedtime for only 6 weeks and it has cut my migraines in half. Still get my normal headaches as well. Would like to give it more time to see how it works. So far no side effects at all."

6 / 10
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8 Report
  • Anonymous
  • Taken for 1 to 6 months
  • October 18, 2012

"Have had migraines for over 20 years. Frequency had increased to more than 15-20 migraines a month. Some would go away with Imitrex or Amerge, some would not. Finally went to see a neurologist (who was a migraine specialist) and we tried several medicines which did not work. She recently prescribed Divalproex Sodium 500 mg, and I have only had one migraine in 4 weeks. Gained 5 lbs but a life without almost daily terrible pain is so worth the possible related weight gain. It is life changing."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • March 16, 2015

"Into the third week became very depressed. I was so tired all I wanted to do was sleep. Than my lower back became so painful I could hardly sit down. I also was getting the twitches and all my joints ached. "

1 / 10
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7 Report

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  • Willa...
  • Taken for 1 to 6 months
  • January 5, 2016

"My doctor prescribed Topamax for migraine prevention, and that gave me too many awful side effects as well as doing nothing for me. He switched me to divalproex, taken twice a day. Much easier to take, with almost no side effects except being a little sleepier and finding it a little harder to focus. However, it's doing nothing for my migraines. And I had such hopes."

1 / 10
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  • Nano
  • Taken for 1 to 6 months
  • February 9, 2021

"I've been struggling with a continuous bi-temporal headache, diagnosed as chronic migraine. I've been taking 500 mg of divalproex sodium (Depakote ER) daily. I've taken it along with 125 mg daily of nortriptyline and 120 mg daily of verapamil as well as a multivitamin. I haven't experienced side effects but I also haven't seen any improvement in symptoms."

5 / 10
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  • Pony...
  • Taken for 1 to 6 months
  • February 15, 2015

"I have had terrible headaches since I was 8 years old and nearly broke my neck in a fall from a bucking horse (0ver 50 years ago). My neck grew all screwed up and I often woke up with headaches on one side of my head and behind my eyes and across my forehead. I always felt nauseated but had to put starches in my stomach to cushion the ibuprofen I was gobbling. Then I started taking 125 mg 2/times daiiy of Divalproes DR about a year a go. My headaches were less right away and no side affects. I'm now taking 250 mg to 750 mg 2/times. Depending on the headache. Getting regular neck adjustments always enables me to reduce back to the 250 mg 2 times daily and I hope to keep it at that level. "

10 / 10
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  • Gabriel
  • Taken for less than 1 month
  • August 4, 2018

"Was given this for a mood stabilizer. As a side I was having headaches everyday constantly for 6 years previously. I had tried Aleve and Avail, and it hardly did anything. After a day of 2 on Divalproex my headaches were gone. After a week my headaches returned so I started taking one at daytime and one in evening (500mg) each. I will see my DR. again in a month because I still feel like I need something stronger, and there needs to be some kind of adjustment so that it last all day."

6 / 10
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  • Partha...
  • Taken for 1 to 6 months
  • August 9, 2017

"I have been experiencing migraine from my teens. It has peaked in the middle age. After retirement it has again started viciously, the neurologist said it is because of pill pooping out. Tried propronolol, topiramate etc etc and even tried valproatete. Finally I tried divalporex ER 500 within days the migraine episodes came down and migraine if any does not progress into throbbing episodes requiring triptans. Gladly it goes away like a normal headache."

8 / 10
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  • Wow
  • Taken for less than 1 month
  • October 27, 2021

Depakote (divalproex sodium) "I had a checkup with my neurologist to discuss migraine treatment. I’d been taking propranolol for about 4 months and it was keeping the migraines with aura days at bay, but side effects were no good. Doc started me on 500 mg Depakote ER and told me to taper off propranolol for the next 7 days. I had a migraine the first day on Depakote, however, the pain associated with migraine subsided rather quickly. After day one, I began to notice a definite improvement in my mood, and my head was not hurting like normal. It’s been about 30 days now and I haven’t had any other migraines, or cluster headaches. I dare say I feel normal. So far, this is the best I’ve felt in 5 years. It works for me, benefits are not having cluster headaches or migraines, and normalized mood. This is easy to use with no major side effects so far."

10 / 10
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  • TMM
  • October 5, 2022

"I’ve had moderate to very severe headaches every day for 13 months. Qulipta did nothing for any of my pain. My Dr put me on Divalproex SOD DR and within a couple of weeks the pain had diminished to barely there to gone."

10 / 10
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  • Emd_
  • Taken for 5 to 10 years
  • February 8, 2022

"I was originally prescribed Divalproex for my epilepsy, which has been incredibly effective, but came to learn years later that it’s used for migraine prevention. I have had almost 100% success with it. I can drink coffee, red wine, eat feta, msg, dark chocolate… all the things that used to give me debilitating migraines are now safe for me to consume. Highly recommend. Bit of a brain fog as a side effect, but not terrible."

9 / 10
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  • MJR
  • Taken for 6 months to 1 year
  • April 28, 2021

Depakote ER (divalproex sodium) "This has been the most helpful migraine preventative - my migraines were becoming a full-time disability and for the first time in a long time I’m hopeful - my doctor added 20-30 mg of Vyvanse (stimulant - a very low dose) to suppress appetite and lethargy and it is amazing - no appetite, no weight gain and I’m energetically working full-time. Fingers crossed it keeps working. Try the stimulant to prevent the weight gain!"

9 / 10
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  • Mantis
  • March 25, 2008

Depakote (divalproex sodium) "Depakote was (and still is) a miracle drug for me with my migraines. I used to get one almost every day, and now it's down to just a few small ones every month!"

9 / 10
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91 Report
  • Renos...
  • October 1, 2013

Depakote (divalproex sodium) "I started back on Depakote 2 weeks ago. My headaches are better but my hands are shaky and my stomach aches. Better than a migraine so I will continue."

6 / 10
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35 Report
  • Jesse...
  • Taken for 1 to 6 months
  • May 3, 2013

Depakote (divalproex sodium) "I went on Depakote 10 weeks ago. My migraines are no different, but I've gained 25 pounds. That's just crazy! Just switched to propranolol and I think my headaches are getting better."

2 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • October 2, 2012

Depakote (divalproex sodium) "Worked well for migraines but had to stop due to double vision, dizziness and 16 pound weight gain in three weeks."

8 / 10
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32 Report
  • depabie
  • Taken for 1 to 2 years
  • May 6, 2017

Depakote (divalproex sodium) "If you want to sleep a lot, as in all day long and gain lots of weight, enjoy. I am listless, and have pre-diabetes now. "

3 / 10
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  • Dee
  • Taken for 6 months to 1 year
  • March 12, 2018

Depakote (divalproex sodium) "Lethargy, weight gain, depression, headaches, muscle aches, nausea"

1 / 10
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  • Anonymous
  • August 5, 2009

Depakote (divalproex sodium) "I have been on the medicine for three weeks and the headaches are still there. Sometimes worse."

2 / 10
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21 Report
  • crims...
  • January 14, 2012

Depakote ER (divalproex sodium) "This has worked better then anything else I've tried. I have gained weight though and I still get the flashes of light and dark spots. "

2 / 10
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  • tlrome
  • Taken for less than 1 month
  • December 27, 2012

Depakote (divalproex sodium) "One dose sent me to the ER with a horrible dystonic reaction."

1 / 10
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17 Report
  • Anonymous
  • September 30, 2010

Depakote (divalproex sodium) "Depakote twice a day worked for the headache, but made me so anxious that I could barely function. Once a day is not working for headache. Guess I have to try something else."

3 / 10
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17 Report
  • Fred
  • October 24, 2020

Depakote (divalproex sodium) "Day one of taking Depakote No difference. But day two, fantastic out of the park. Went fishing for the first time in years!. 250mg once a day before bed. Day 3...we shall see."

10 / 10
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6 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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