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Dihydroergotamine for Cluster Headaches User Reviews

Brand names: Migranal, Trudhesa, D.H.E. 45

Dihydroergotamine has an average rating of 8.8 out of 10 from a total of 8 reviews for the treatment of Cluster Headaches. 88% of reviewers reported a positive experience, while 0% reported a negative experience.

Dihydroergotamine rating summary

8.8/10 average rating

8 ratings from 8 user reviews.

Compare all 27 medications used in the treatment of Cluster Headaches.

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  • Anna...
  • February 13, 2018

Migranal (dihydroergotamine) "I was told about this medicine from an older friend whom had horrible, debilitating migraines all her life and was light and sound sensitive. I would lock myself in a room and hope for it to pass. I was prescribed migranol. The active ingredient is actually a fungus. It has been around since ancient Roman times. (look it up..pretty interesting ) yes, the mark up is somewhere between 250%, the insurance pays $4,500 for 8 bottles. Yes, there is "No" generic and the company that makes it is from France. Yes, if you take it incorrectly, you will taste it in your mouth and swallow it. Please read the instructions all the way!!! Take in the first 5 minutes of a migraine..it will be less effective if it's a full blown migraine. Takes my migraine away about 75%. No high(unless mixed with other drugs), no drowsy or lingering effects. I will continue to take unless my insurance says no more. Important stick to the dose and don't go over as the toxic effects are dangerous - but its not toxic at correct dose."

9 / 10
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6 Report
  • Brand...
  • July 4, 2014

Migranal (dihydroergotamine) "I have suffered with clusters for the last 20 years. Every time I've been prescribed something that works, the FDA finds a negative reason to stop production. Migranal seems to work really well, but the price is ridiculous!! My pharmacist requests that I only get it at the end of the month due to his cost. Now my insurance cost on it is being raised. Go figure....."

9 / 10
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7 Report
  • Pwrna...
  • Taken for 5 to 10 years
  • October 29, 2016

D.H.E. 45 (dihydroergotamine) "For me with Chronic Cluster Migraines the Dihydroergotamine injections eliminates the migraine within 30 minutes and is best. I also use cold neck pack, keep in the freezer, and Oxygen, I have an oxygen generator set at 6 ml. I used to use Migranal, similar side. Migranal is not covered by Medicare/AARP United Healthcare ($500 retail each),but DHE45 is. Preferred plan appears to have best benefits but still expensive. Instead of 1 ml dose, I cut back to .35 ml and get 3 shots from each ampule, still works great for me. I fill 3 needles and keep available. DHE not available due to manuf shortage (Valient) until Jan, 2017 and they are only supplier. Waiting 2 months will be difficult so I have to ration."

10 / 10
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5 Report

Frequently asked questions

  • NJA
  • Taken for 2 to 5 years
  • November 7, 2022

"It was a good abortive for my Cluster Headaches CH when I used at the beginning of the attack. I even used it to decrease my post exercise headaches but using a quarter of a pill. I stop using this drug because it cause numbness in my hands fingers meaning it was messing with my circulatory system…"

5 / 10
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0 Report
  • Anonymous
  • Taken for less than 1 month
  • July 19, 2012

Migranal (dihydroergotamine) "I have suffered from cluster headaches for 7 years. My doctors have tried it all on me then one day I was administered this. A God send after so many years of pain and emotional turmoil."

10 / 10
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20 Report

Are you taking this medicine?

  • Kensi
  • February 11, 2016

D.H.E. 45 (dihydroergotamine) "Excellent. It worked to break the cycle without many side effects"

8 / 10
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4 Report
  • Clust...
  • Taken for less than 1 month
  • August 10, 2014

D.H.E. 45 (dihydroergotamine) "Rough side effect profile (nausea, leg cramping, and the injections burn). Have used every day for a couple weeks to shut down a bad cluster. Worked pretty good."

9 / 10
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4 Report
  • Henry
  • Taken for less than 1 month
  • November 25, 2019

"dihydroergotamine is the only medication that works for my headache. It works very good"

10 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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