The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.
Migranal (dihydroergotamine) for Migraine: Works well to treat migraines but you really need to rest after taking. I get an unpleasant burning sensation in nose, sinuses and throat, but still worth taking. Also, the bottle is a pain in the butt to assemble - especially when you have a migraine. I have frequent severe migraines (about 4 times a week) and this medicine is helpful although my dr. said it should not be used more than twice a week. I am allergic to all the triptans, so this medicine has been a good alternative treatment.
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Migranal (dihydroergotamine) for Migraine: I give it a 10 because I was about to jump off a bridge in order to break the 18 day migraine I had up until this morning. It took 3 days of Migranal but I am FINALLY through the pain. I tried two rounds of steriods, Maxalt up to 3x's/day for 2 weeks, and FINALLY this worked. Although I am cautiously optimistic, this is the longest I have gone in 18 days without the debilitating pain that became so severe I was willing to go to very extreme measures to get it to stop. Thank goodness my Neurologist thought of it.
Migranal (dihydroergotamine) for Migraine: I have migraines usually 3 to 5 times a week and my neurologist gave me this medicine. I am also taking propranolol and have not noted any side effects. I have found that for me it works best when taken at first signs of a migraine. If I take it when I already have a migraine it doesn't work. There is a little nausea afterward but a little food helps. It's a very effective treatment and no rebound headaches.
Migranal (dihydroergotamine): I used the Migranol for the first time this morning. It worked with the first pump. I followed with the second pump as directed, as there was a slight "buzz" left after the first pump. It worked very well. I did find myself to be very sleepy, whether that was a reflection of the medication, I can't say, but the migraine is gone. I now take a daily preventative (Topamax) and have been taking Midrin when I feel a headache starting, hopefully this will eliminate the sleepy feeling that I often get with Midrin. However... It didn't.. I'm sleepier with the Migranol than I am with Midrin.. BUT the headache was gone faster than with Midrin. It's a matter of choice at this point.
Migranal (dihydroergotamine) for Migraine: My neurologist gave me a sample of this spray during my last office visit. We're going the non-Triptan route trying to manage my migraines since I previously had a reaction to Triptans. This spray did nothing for my latest migraine at all. In it's defense my migraines are pretty severe and even hard core narcotics aren't much of a match for them. The search continues.
D.H.E. 45 (dihydroergotamine) for Migraine: I have had severe migraines for years. I finally was put on Topamax about a year ago but that wasn't enough, I still had attacks that kept me from doing anything about 2 times a months. None of the triptans worked so my doctor finally suggested DHE injections. She taught me to give them to myself so I can do them at home and now I can stop a migraine when it starts and not miss work for days on end. If anything I miss one day here and there.
Migranal (dihydroergotamine) for Migraine: I get very frequent migraines, up to 15 per month. Have tried just about everything, including narcotics to control migraines. I am currently on Inderall daily as preventative (have tried many, many, other drugs as well). Am currently taking Maxalt and Treximet, but doctor suggested we try the nasal spray. I had a full blown migraine when I tried it, so results may be a little off. Migranal caused burning in the nose, and throat, nasal congestion. It also left a nasty taste in my mouth. Woke up the next day with the migraine still lingering.
Migranal (dihydroergotamine) for Migraine: Migranal Nasal Spray seems to have helped the migraine (within the 24 hours, not quickly). However, the muscle pain was tremendous for 48 hours following taking the 1st & 2nd doses. I changed from Triptans because of the muscle pain, but the pain with the Migranal is worse. I will try it one more time, but if the after effect (excruciating muscle pain, especially in my legs and feet) are as bad as my first experience, I will stop.
D.H.E. 45 (dihydroergotamine) for Migraine: I had several days of DHE IV's, a good try of migraines. A few weeks of injectable DHE and it didn't do a thing for me. I wish it worked for my constant headache. I heard a lot of good things about it.
Migranal (dihydroergotamine) for Migraine: I have been getting severe migraines for more than 25 years. 99% of the time they would result in a trip to the ER for a few injections - since I can't keep anything in my stomach, pills were not a solution. Suppositories to control the vomiting so that I could take pills only made me more miserable - in other ways - and offered little to no benefit. Last year my neurologist prescribed Migranal Nasal Spray. Wow. What a life changer! Within 30 minutes I am good to go with little to no remaining headache. There isn't even enough time for the vomiting to start. I really want to spread the word on this to other migraine sufferers. It has been an amazing solution for me.
D.H.E. 45 (dihydroergotamine) for Migraine: I've been experiencing migraines for over 30 years. I started injecting DHE 9 days ago and haven't had a single migraine. This hasn't happened since I started getting migraines and I've been on many medications including Botox. I don't expect to never get another migraine but I'm enjoying this time while it lasts. I do believe that the DHE will control my migraines and keep them to a minimum which has never been done before. I normally average 25 migraines a month. If DHE can reduce my migraines to once a week, I'll be thrilled.
Migranal (dihydroergotamine) for Migraine: My neurologist prescribed the Migranal for me last year when I got into a 2 mth long migraine that was seeming to be impossible to break. I'm also on Nortryptiline and Atenolol as preventatives and the Migranal is for PRN usage. (as needed) As someone else said, this drug does seem to work the best if you use it at the first sign of migraine. If you wait until your migraine is fully set in, it doesn't seem to work all that well. The downside to the medicine is that is does leave a terrible taste in your mouth, your throat burns, and your nose gets stuffed up. But compared the to severe pain of a migraine, I guess it's worth it. The worst part about it though is the COST.
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