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Cyproheptadine User Reviews & Ratings (Page 5)

Cyproheptadine has an average rating of 8.2 out of 10 from a total of 204 reviews on Drugs.com. 76% of reviewers reported a positive experience, while 10% reported a negative experience.

Reviews for Cyproheptadine

  • scull...
  • September 27, 2015

Periactin (cyproheptadine) for Migraine "Cluster migraines made my life a misery. New doctor, new approach, and with Periactin of 5 x 4mg at night has changed my life. Yes, be careful with the weight gain, and the sleepiness abated after two weeks. Some strange dreams as well."

9 / 10
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28 Report
  • Birddog
  • April 16, 2014

Periactin (cyproheptadine) for Migraine "My 4 year old was diagnosed with migraines (3-4 per month with vomiting and other symptoms). Given Periactin. Has had quite an increase in appetite and thus weight gain. It's difficult as a parent to balance the weight gain and social issues with that. Will try going off Periactin in summer per Neurologist. Hopefully the migraines will stay away and she will be able to lose some of the weight."

9 / 10
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31 Report
  • Melisa
  • October 11, 2017

For Anorexia "For me being skinny never felt right. I was skin and bones all the time and that really affected my self confidence. In 2011, my mother introduced me to this medicine and I love her extra for it. I moved from being just 110 at 5ft 11ins to 155 in a few months. A month ago when i checked my weight I was 170lbs, damn how I was happy about it. But now I am going through a stressful time in my life (he got someone pregnant) I have already lost 7lbs. I am back on this medicine again and hopefully I gain the lbs I lost recently. It does make you really sleepy at first but then I feel like my body got use to it."

9 / 10
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22 Report
  • Anonymous
  • Taken for 5 to 10 years
  • May 26, 2013

For Migraine "I have been taking this since I was about seven years old to fight off the migraines I was experiencing, almost daily, that would send me home from school. My doctor prescribed this to me, and almost 10 years later my migraines are practically gone. Now and again I'll feel the sensation of a headache coming on, and I still take it to fend them off. The only thing is it causes me to become drowsy, and often puts me to sleep sometimes. I've learned to take it after my meals in the evenings because of this, so I'll wake up refreshed in the morning."

10 / 10
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32 Report
  • CLano
  • Taken for less than 1 month
  • November 3, 2018

"I've been small my entire life. I only gained weight during my pregnancy in 2011, which I was like 170 lbs and after giving birth I was back down to 110. It took no time. I ate food thinking I would keep some of the weight. However, that didn't work out. Now I'm 28 going on 29 in 2 1/2 months and my weight is a big thing to me. I'm the smallest out of all my friends and family and it bothers me. I went to the Dr 10/23/2018 and asked if I could be prescribe anything to help me gain weight and give me a better appetite and this is a miracle. I got my prescription filled the exact same day weighing 110 lbs and today is 11/2/2018 and I weigh 117.8 lbs. I can tell the weight gain by the way my clothes snug a little bit more and I'm happy. Next week I start working out to stay in shape while taking these pills."

10 / 10
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19 Report

Are you taking this medicine?

  • Mom
  • Taken for 1 to 6 months
  • July 18, 2017

For Anorexia "I've been thin my whole life. Never weighing more than 100lbs. I have two children and at almost 30 I was 5'9 110 lbs when I found this medicine. It started working within days. And I love it. I'm not much for taking pills everyday buts its worth it. Its the only thing that's worked for me, and everyone has noticed the diff.Haven't stepped on a scale yet."

10 / 10
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22 Report
  • Anonymous
  • November 9, 2008

For Anorexia "My son has been taking this medication to help gain weight. It has helped his appetite and seemed to help with his morning sneezing also. We give him a teaspoon in the evening and he is hungry before bed and eats more in the morning now."

8 / 10
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40 Report
  • Gainer
  • Taken for 1 to 6 months
  • July 16, 2021

For Anorexia "Please only use this through prescription. The ingredients found in GML-apeti and apetamin are NOT the same as the prescription. I tried all three and honestly, the prescription works way better with less side effects. GML has other things added, the prescription is just strictly cyproheptadine. Be careful out here."

10 / 10
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11 Report
  • Jessi...
  • August 1, 2016

For Anorexia "Ive always been skinny but not to a point where people would point it out or say i need to gain weight. I tried taking this because sometimes ill lose my appetite and i can go days without feeling hungry. I took half a 4mg at night before bed and i couldnt get out! I slept from 10 pm all the way to 1:30 in the afternoon and i was still tired! It makes your bones feel like jelly. It does help you gain weight but when i took it, all the weight just went to my stomach. So now im just forcing myself to eat more and i hit the gym 5 times a week for weight lifting and i look better than when i used this pill to gain weight. If you want to put on healthy weight aka muscle this isnt the pill to try- 16lbs of muscle =1 year to put on."

7 / 10
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23 Report
  • Buffers
  • Taken for 2 to 5 years
  • September 15, 2018

For Migraine "I was getting migraines and I could not find anything to control them. My allergist recommended this drug. It has been a life saver! Yes, I have read what other people has said about it, but I would make a suggestion - as my doctor told me. It does make you sleepy - so you take it only at night before you go to bed. I wake up fully refreshed. I have been taking this medicine for over two years and have gained NO weight . If you suffer from migraines, I highly suggest you try this. I might have had 1 migraine attack in the past year. I would say that it works very well."

10 / 10
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18 Report
  • Sunfl...
  • Taken for 1 to 6 months
  • January 19, 2021

For Anorexia "I have never been diagnosed with anorexia, but I have always been skinny. I have always had a high matabolism. My Dr prescribed me this medicine cyproheptadine and it has increased my appetite so much. I'm constantly always eating, and I finish every meal! I'm craving food all the time and I have gained 6 pounds!! I was 88 pounds before I started taking my medicine, and my Dr is so happy to know I have gained weight. I totally recommend this medicine 100%"

10 / 10
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12 Report
  • Nummie
  • November 20, 2011

Periactin (cyproheptadine) for Allergic Reactions "Started this medicine 2 days ago. Slept for 14 hours straight. Hunger just kicked in and I ate a huge sandwich and drink and I'm still hungry. Changed dose to 1/2 of 4 mgs and got up this morning normally. I intend to build up slowly because of the sleepiness side effects. I intend to stay on this due to my fast metabolism and stress to get back to normal. I think it is working!"

9 / 10
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32 Report
  • Preci...
  • Taken for less than 1 month
  • October 11, 2019

For Anorexia "I'm not anorexic but I'm a really small woman right now and can not gain weight at all. I have a nutritionist and still no difference so I went to my Dr on 10/8/19 and so far my appetite has picked up over 50%. I'm eating more off my plates and snacking a lot more than usual. I see where people are starting off taking whole pills right away but my Dr told me a half a pill (4mg) 4x a day for 21 days then 2 whole pills 4x a day. I was at 100lb but I haven't weighed myself but will my next appt. I see my nutritionist 10/26/19 and I'll get weighed in. I'll check back in then but if no change then I'll check in in 2 months when I see my PCP for a check up,and the best thing about it is my Medicaid pays for it. I'm also hypothyroidism so you'd think I'd gain weight alone. I have severe allergies living in Oklahoma lol and take allergy medicine with inhalers as well everyday and if this also helps with allergies then I can kill 2 birds with one stone and stop the inhalers and montelukast."

8 / 10
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15 Report
  • Deezy...
  • February 6, 2017

For Allergic Reactions "This medication works wonders if you are looking to gain weight. I personally take these for allergies but have noticed weight change within 2 weeks of using it. I was 180 and gained 5 pounds and I'm 5'9. Not too stoked on gaining weight but I'm not disappointed either would definitely recommend if you suffer from loss of appetite or other medical conditions."

10 / 10
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20 Report
  • Texas...
  • Taken for less than 1 month
  • April 12, 2016

For Anorexia "1 - My 11 yo was placed on this to "increase her appitite". Guess what? It's hard to eat when your sleeping all the time. 10mg, 1st day I gave it to her on Friday she slept for 18 hours! For 1 week, I was scared to give it to her before school. So I restarted her by cutting it in half and after 5 days, I gave her the whole 10mg. Today I got THE CALL from her Teacher. She is telling her friends she wants to DIE!!! PILLS ARE IN THE TRASH CAN!"

1 / 10
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21 Report
  • JayWi...
  • Taken for 1 to 6 months
  • September 16, 2015

For Anorexia "Started taking 2 pills a day. Im 6'4" and only 110 pounds. Took this for 2 months and the only thing that happened was me falling asleep constantly during class. Hurt my grades and did absolutely nothing to my appetite,"

1 / 10
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22 Report
  • Anonymous
  • April 9, 2012

Periactin (cyproheptadine) for Migraine "I was pregnant, I had to stop taking Relpax (at 2 x a month) for migraines and I made notes and found I had horrible pain 20 out of 30 days in the month. For 2 months I suffered and my ob referred me to my neuro who referred to my ob and no one would help me. A new neuro put me on Periactin 4mg once a day. I started it on -I think day 2 of what usually is a 3 day migraine and it stopped. I had only a faint sensation of a headache. "

10 / 10
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28 Report
  • RedSc...
  • Taken for less than 1 month
  • August 4, 2016

For Migraine "It got prescribed this when I started getting horrible headaches almost daily. I was told to take it two times daily, once in the morning and once at night. It gave me more headaches, at least an aura without pain. I had increased blind spots in my vision. As well as it made me extremely tired. Stopped taking it."

1 / 10
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20 Report
  • Happy...
  • Taken for 1 to 6 months
  • May 26, 2017

For Anorexia "This s the 2nd time I'm sharing this experience! I think first it didn't work on me! Still I continued using it! I was a lazy person earlier but now I've started working in office and I walk about 3 km everyday! It's been 1 week since I started working and walking my appetite is same but but but I gained 3 kg in a week and I'm gaining! I weigh every day and the weight is always increasing!! I am 51 kg now hope I'lll reach 60 soon. I'm 5 feet 8 inches tall~!"

9 / 10
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18 Report
  • Jeaneem
  • Taken for 1 to 6 months
  • December 6, 2012

For Migraine "My 7 year old son has had these severe headaches, now believed to be migraines, since he was 3. With time the headaches have become almost daily. One month to the day. My son has had only 1 headache!! He has gained weight though, which for him was ok because he was so so skinny."

9 / 10
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26 Report
  • Ris
  • Taken for 2 to 5 years
  • November 27, 2019

For Anorexia "Took periactin once a day as it made me very drowsy and heavy headed. Although my appetite picked up a lot and over a year I put on about 10 kgs which I wanted, but it was the worst decision to take these tablets as it caused severe dryness in my eyes. Which has led to terrible eye pain day and night. Sadly I didn't make the link between the tablets and the pain till too late but have now stopped taking them. They probably work for some without side effects but not for me unfortunately."

1 / 10
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  • Owie...
  • Taken for 1 to 6 months
  • February 18, 2016

For Migraine "Prescribed this for my four year olds presumed migraines (vomiting, light sensitivity) MRI revealed a chiari malformation. It has helped tremendously. He still suffers an occasional headache but they are fewer and farther between. The increased appetite has been a blessing. He was losing a lot of weight due to another condition and has since stabilized."

8 / 10
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20 Report
  • Sarah...
  • December 14, 2017

For Anorexia "I tried this on a whim, after reading a lot of reviews. I was a little nervous, as my doctors have never heard of it. Still, I took the chance because I was desperate, and I've gained 15 pounds in 3 weeks! I'm still in shock. My stomach somehow turned into a bottomless pit. I will say though, I kept falling asleep for the first 3 days. Like, deeeeeep sleep. And I had the worst headaches of my life. BUT, it subsided after about 3 days. I still get a little drowsy and disoriented at times, but I don't take it as often now. I started with 3 doses of 4 mg/day, and now I take it once before bed."

10 / 10
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16 Report
  • nish
  • Taken for 1 to 6 months
  • November 28, 2023

For Anorexia "I've been using it for 4 months and I've gained so much. It's nice to have this nice body. Everyone I meet keeps praising how great I look... It boosts your appetite and makes you feel hungry and sleepy in the first week, but after that, it's a smooth ride. At times when I'm broke, I take half a pill and it still does the magic. Thank you, cyproheptadine, for changing my physique ☺️"

8 / 10
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2 Report
  • Virgo...
  • Taken for 6 months to 1 year
  • August 16, 2017

For Anorexia "This is the only thing that has worked for my poor appetite! I've always struggled with having little to no appetite and feeling like I was "too thin". I've been taking these pills for months now and I can honestly say that I went from 99lbs to 130lbs. I look extremely healthy and happier. It has some cons too. Your body will start to get used to it and you will most likely lose weight and your appetite if you discontinue it. It also makes you extremely tired so take it before bed or on your days off"

8 / 10
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15 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.