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User Reviews for Carbidopa / levodopa

Also known as: Atamet, Duopa, Parcopa, Rytary, Sinemet, Sinemet CR

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Carbidopa/levodopa.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Restless Legs Syndrome 14 reviews 15 medications
   
8.9
Parkinson's Disease 10 reviews 49 medications
   
7.6
GTP-CH Deficiency 0 reviews 5 medications Not rated - Be the first
Neuroleptic Malignant Syndrome 0 reviews 5 medications Not rated - Be the first
Summary of Carbidopa/levodopa reviews 24 reviews 8.3

Reviews for Carbidopa/levodopa

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Rytary (carbidopa / levodopa) for Parkinson's Disease: "I've been on Rytary for 6 weeks. I take it 3 times a day, 3 pills at each dose. It is unpredictable at times. There are days that I get a full 6 hour benefit without wearing off. But food creates a problem with its effectiveness. There are other times that I'm on an empty stomach, but it does not allow me to have mobility until it kicks in. Other times it kicks in right away, then there's a period not working so well , and then it works again at the 5th hour. I'm really studying all the variables such as my sleep, food intake and stress levels. If I have stress, Rytary ceases to work. Perhaps I need to increase my dose. I'll discuss with my doc this week. But overall it has been much better than Sinemet which gave me 2 1/2 hours."

   
6.0

54 yr old (taken for 1 to 6 months) June 14, 2015

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Rytary (carbidopa / levodopa) for Parkinson's Disease: "I have been taking Rytary for the last 9 days, and it worked great at night since I was sleep. But it worked about 30%-40% for me as soon as I put something in my mouth. I had a small apple yesterday and took my pills 2 1/2 hours later, and I was stiff, with almost no movement for the next 2 hours. Today I had a very light vegii lunch at noon, took Rytary at 3pm which worked about 30%, and I finally decided to take my Parcopaat 6pm on top of Rytary! I would vote for Rytary at night only."

   
3.0

Banoojun (taken for less than 1 month) March 12, 2015

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For Restless Legs Syndrome: "This combination has kept my restless legs syndrome at bay. Occasionally, I'll feel the symptoms between doses, so I take a 1/2 pill, which seems to take care of the problem. I don't think I have any side effects from it. All in all, I'm very satisfied with this medication."

   
10

blond_swede (taken for 1 to 2 years) November 7, 2014

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For Restless Legs Syndrome: "Been on this for going on 15 years now. It has worked so well for me that I haven't even bothered to try the newer things out there. I very rarely have to take more than one even after taking it for this length of time."

   
10

Deej416 June 19, 2014

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Sinemet (carbidopa / levodopa) for Parkinson's Disease: "My mom just celebrated her 1 year anniversary on Sinemet so I wanted to share an update to give anyone newly diagnosed hope. Her dose is now 4 tablets a day (25/100), which she takes at 9:00am, 1:00pm, 5:00pm and 9:00pm. We increased from 3 tablets a day probably around month six, and she's been really doing well since then. No tremors, no obvious rigidity (or any Parkinson's symptoms at all), good appetite. Zero side effects from the Sinemet, which is why I say "celebrated." This is a remarkably effective and very affordable medication. Mom will turn 88 in May. Wishing everyone the success that we have had. God bless."

   
10

Dottie's daughter (taken for 1 to 2 years) April 2, 2014

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For Restless Legs Syndrome: "I'm just beginning to use this medication for restless leg syndrome so far I have noticed this will help me sleep at night."

   
9.0

Alicia R (taken for less than 1 month) September 17, 2013

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For Restless Legs Syndrome: "This medicine has provided effective relief this past year. Timing is everything. I am finding I need to take earlier in the evening as it may take as long as an hour and a half to kick in. Then effects wear off by 3:30 am or so and another dose is needed to get through the rest of the night."

   
8.0

nras (taken for 1 to 2 years) September 4, 2013

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Sinemet (carbidopa / levodopa) for Restless Legs Syndrome: "I have been on Sinemet for at least 15 years. I have not had to raise the dosage due to augmentation as of yet. This is the very first medicine I tried for restless legs syndrome and it works so well for me I don't feel the need to try the newer medicines. I have had restless legs syndrome since my teens and am now hitting 60."

   
10

deej416 (taken for 10 years or more) August 19, 2013

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Sinemet (carbidopa / levodopa) for Parkinson's Disease: "I wanted to share an update on my Mom's status with the hope this information helps others. My Mom's been on the Sinemet now for five months. She's still taking 3 tablets a day (25/100)-- one in the morning upon rising; one early afternoon and one in the evening. She's had no side effects that we are aware of, and up until the last three weeks has been really doing well. Now she's starting to have increased fatigue and some confusion-- not terrible, but noticeable. I'm taking to her neurologist in two weeks to see if she needs a small increase in her dose. He said her current dose (1 pill three times a day) is low, and there is room to increase gradually. Mobility is still excellent and tremors are barely there."

   
10

Dottie's daughter July 18, 2013

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Sinemet (carbidopa / levodopa) for Restless Legs Syndrome: "I worked on my feet for 10 years now and developed restless leg about 2 years ago. No one understands what it is until they've encountered it themselves. I am prescribed Sinemet and I love it. I usually only take it when symptoms start (when those legs start a feeling funny). I am very fortunate because I suffer no side effects. I do not get sleepy and it doesn't bother my stomach. I would highly recommend this medication for anyone who is unfortunate enough to suffer from this."

   
9.0

MasonsMommy May 14, 2013

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Sinemet (carbidopa / levodopa) for Parkinson's Disease: "My mom has been on generic Sinemet for 8 weeks, and her improvement is remarkable. She's 86, and until the last 18 months, she had never taken any medication and was energetic and bubbly. She had a dramatic and fast onset of Parkinson's, and prior to starting this medication, she was almost completely debilitated. She looked like she was slowly dying. She lost a lot of weight, was shuffling, stooped in posture, exhausted, and confused. We took her to a neurologist who started the Sinemet slowly over a series of three-day incremental increases, and she started showing improvement almost immediately. She now takes 1 tablet three times a day (25/100). Zero side effects. And, now, two months into this, she's 75% back! It's a miracle!"

   
10

Dottie's daughter (taken for 1 to 6 months) March 28, 2013

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Sinemet (carbidopa / levodopa) for Restless Legs Syndrome: "This has been a God send for me. I have been prescribed carbidopa-levodopa 25/100 for 10 years and am currently 53 (age). While it may affect others differently, I have seen absolutely no side effects. If I am beginning to feel restless legs syndrome, this medicine seems to take about an hour to eliminate the symptoms. Since these symptoms seem to come over me as I relax into the evening, I simply take one in advance and another just before bed. I also take it just before long drives and flights. Works great for me and I hope others may be as fortunate. I tried Requip at one time but it made me groggy."

   
10

KevinP504 (taken for 10 years or more) December 13, 2012

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Sinemet (carbidopa / levodopa) for Restless Legs Syndrome: "I have had restless legs syndrome for years due to iron deficiency. I took Sinemet for about a year and it seemed to work great for me. However, I could not take the full or even half of the dose because it really made me feel drowzy the following day so I would break it up and take a very small piece of the pill. Also, if you don't go to bed after taking it and stay up for a while, it can have the adverse effect on you. Makes you really sleepy, but make your restless legs symptoms worse. Good Luck!"

   
8.0

Amy Darrell February 20, 2012

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Sinemet (carbidopa / levodopa) for Restless Legs Syndrome: "I suffer from restless legs syndrome since 14 years ago and been taking Sinemet since. The only medication that works for me but only lasts for 2 to 3 hours then need to take again. For about nearly 2 years I came to realize that after eating food or drink contain msg/monosodiom glutamate - 621,627 which will contribute my suffering so if I eat less of this and will be less suffering. "

   
8.0

Kampret January 20, 2012

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For Restless Legs Syndrome: "I have had restless legs syndrome for over 15 years. It has gotten worse over the years, but with my doctor increasing my medication, my symptoms have been for the most part under control."

   
10

Anonymous January 10, 2012

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Sinemet CR (carbidopa / levodopa) for Restless Legs Syndrome: "Watch out for increase in restless legs syndrome (augmentation) at higher doses. Info I found says should NOT be taken every day for RLS, not more than 3 times per week."

John U December 28, 2011

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Sinemet CR (carbidopa / levodopa) for Parkinson's Disease: "I started Sinemet 25/100mg and within 2 hrs my tremor stopped. I still get some but not as bad as before. My walking also improved."

   
7.0

webbtown November 28, 2011

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Sinemet (carbidopa / levodopa) for Restless Legs Syndrome: "It is working great for me and unlike other medications it is not a controlled drug nor addicting."

   
9.0

Anonymous May 15, 2011

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Sinemet (carbidopa / levodopa) for Restless Legs Syndrome: "I have Restless legs both at night and during the day. The Sinemet helps some at night, but doesn't last through the night. I can't take it during the day because it makes me sleepy and upsets my stomach. If I take it with food it doesn't work at all. I have a heart condition, so there are some medicines I can't take."

   
5.0

Pat621 October 2, 2010

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Sinemet (carbidopa / levodopa) for Restless Legs Syndrome: "Sinemet works great for my restless legs syndrome, even better than the drugs more popularly prescribed. It is absolutely the one medication I cannot live without!"

   
10

Anonymous August 20, 2010

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For Parkinson's Disease: "After many medications and several diagnosis, just after once day since I was put on this medication I feel like part of my life is regained."

   
10

terry37 August 18, 2010

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For Parkinson's Disease: "All it took was one dose and I could walk normally. Minimal side effects after 5 years on it."

   
10

marcie64 December 7, 2009

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Sinemet CR (carbidopa / levodopa) for Parkinson's Disease: "I was placed on Sinemet CR (1 x 4 times daily) as a result of Sinemet "wearing off". I am a carer for my wife who is extremely disabled, thus I needed a medication which allowed me to still manage her needs whilst controlling my Parkinson's. CR has worked and although I have episodes of trembling as I get nearer the end of an 6 hour medication cycle I am very happy with it as I am able to tend to my wife's medical needs and carry out cooking duties as required."

   
8.0

michmal September 8, 2009

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Sinemet (carbidopa / levodopa) for Parkinson's Disease: "Overall was an effective drug for me, but had problems with it wearing off between doses."

   
7.0

wv_picker September 4, 2009

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