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Amitriptyline for Fibromyalgia User Reviews (Page 3)

Amitriptyline has an average rating of 6.5 out of 10 from a total of 103 reviews for the off-label treatment of Fibromyalgia. 46% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Amitriptyline

  • jayrose
  • September 29, 2016

"I been suffering with fibromyalgia for 6 years diagnosed officially for two. I have IBS, RLS, Insomnia, depression and anxiety as side effects.I've been through the mill trying to find something that works to ease it. Had a winning combination of tramadol and mirtazapine taken on a night which eased the pain symptoms so I could sleep. However it didn't help with the pain but I could live with that. My Dr. decided that I couldn't and took me of tramadol and put me on amitriptyline and much like it's name I felt like I'd tripped. I was awake but had no control over my limbs I could still feel the pain the twitches. I felt like I was locked out of my brain and someone else was at the wheel. I will never take it again."

1 / 10
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27 Report
  • barbie...
  • September 7, 2009

Elavil (amitriptyline) "I started on Elavil about 15 yrs ago for fibromyalgia. It brought me a lot of relief at first but it stopped working for me. I still take it but the doctor wants me to take a lessor mg. I was up to 100mg but now I am down to 20mg. She said that the Elavil made my heart beat really fast. It can also make your blood sugar go up or down."

6 / 10
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44 Report
  • kjg
  • May 28, 2009

Elavil (amitriptyline) "This medicine did not help my fibromyalgia at all. I had Doctor after Doctor ask me to take it as I searched for answers and relief. I finally had to stand up for myself and refuse to take it because it has such a strong effect on me. I felt like a zombie each time I tried it. This is regardless of how small the dose was. The medicine did nothing to ease my pain or any of my other fibromyalgia symptoms. "

1 / 10
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Frequently asked questions

  • tjay
  • Taken for 6 months to 1 year
  • January 12, 2016

"I've used Amitriptyline for about 6 mnth now I sleep well, little harder to get up in the morning, It doesn't help my pain, but I do find I'm able to cope better. Also I find using deep heat heat rub helps. I rub it into my muscles. My doctor says it ok as it an anti inflammatory."

7 / 10
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28 Report
  • mallo...
  • September 29, 2015

"After reading some of the reviews I just want to say that amitriptyline is not prescribed to help with the daily pain of fibromyalgia. It is used to help ease the other symptoms it can cause. If you are taking it in hopes that your daily aches and pains are going to go away then I suggest you see a different doctor and try something else. I take Savella also and that has helped me a great deal. But I am using amitriptyline because I suffer from tension headaches and migraines. Out of the month, I can go every day with a headache. I have not been on it long enough to give you a full review but since I have been on it I can say that I am sleeping much better and my headaches are getting better. I have been on it for a little more than a week."

7 / 10
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29 Report

Are you taking this medicine?

  • DBMCG
  • June 27, 2016

"I've had fibromyalgia since I was 14 years old. It was not diagnosed until I was 20 at that time I took 3600 milligrams of ibuprofen a day and 40 mg of prozac. After many years I finally went to a rheumatologist who had me on elavil 40 mg. I take that and my 40 mg or prozac and have no fibromyalgia pain any more. I do however have the side effects of fibro fog, short term memory loss. It's very scary I want to stop all medicine but am afraid. The elavil acts like a prophylactic to complicated migraines for me as well as helping me sleep. Any advice from anyone. I've been on medicine for 30 years now. thanks"

10 / 10
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27 Report
  • Tondra
  • Taken for less than 1 month
  • November 30, 2017

"I am a 66 year old post-premenopausal female with Fibromyalgia. I was given Amitriptyline to treat my condition. After 6 days on this medication, I began experiencing lower abdominal cramping and on the 7th day, started vaginal bleeding. I immediately stopped the medication, but the bleeding continued for 7 days. After researching, I found that in studies of 854 women, 2 experienced bleeding, both were over 60 years old."

1 / 10
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22 Report
  • JJ85
  • Taken for less than 1 month
  • May 25, 2015

"Used it for a month started at 10 mg-20 mg. One of the worst drugs I have used. It left me so sedated that I couldn't wake up in the morning and wanted to sleep all day. It helped with head aches but I couldn't concentrate, felt overly emotional, crying and angry. I found it hard to drive from lack of focus 18 hours after taking pill. I had a deep sleep, but not a restful one, the dreams were bizarre. Dry mouth and irritable too. Not worth not having a headache to have all of these problems. I am very sensitive to medication as I don't drink so it was not for me. Oh and I gained three pounds in first two weeks using it."

1 / 10
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28 Report
  • amaur...
  • October 19, 2009

Elavil (amitriptyline) "I started on 25 mg of Elavil for 1 month and recently increased to 50mg. The Elavil has worked well to some extent. I didn't have very many side effects and I am hoping that it will continue to give me positive results."

7 / 10
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39 Report
  • Jello
  • April 27, 2020

"I have tried Cymbalta and Lyrica for fibro pain...both caused severe cognitive fog & memory loss. Gabepentin didn't help the pain. Amitriptyline worked for the pain until I started gaining more and more weight. I have scoliosis and the weight gain was excruciating for me. So I guess I'm back to T3s every 4 hours. The only thing that seems to work for the pain and doesn't cause side effects."

6 / 10
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  • It Wo...
  • November 5, 2015

"I also have Fibromyalgia and Stenosis, and for five years my doctors prescribed many different medications.....finally I have a combination that puts me to sleep, KEEPS me asleep (before I'd wake up a dozen times a night) and I have NO side effects. I'm taking 90mg of Cymbalta once a day, 7.5 Norco three times a day, 10mg Valium three times a day and Elavil 25mg at bed time. I still have pain and stiffness but I can sleep thru the night. My mood has improved and I'm better able to deal with my health issues and life situations. It took a long time to get to this point but it was well worth the wait as I am sleeping 8-10 hours a night now, my dark circles are nearly gone and I'm happier because I feel rested."

9 / 10
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23 Report
  • TKN
  • Taken for less than 1 month
  • November 6, 2015

"I just took the first dose of 10MG last night for Fibro (which I've had for 20 years). It's now 10am and I can't get out of bed (I usually get up before 6am). I have a 6 year old and struggled to get up to get her ready this morning. There's no way I can make it to work this morning. I'm so out of it and I feel horrible. Hope the groggy sleepiness wears off soon! I cannot see me continuing to take this. I cannot speak to whether it would work for Fibro BUT my experience with fibromyalgia is anything that lets you get sleep will help. This used as a sleep medication is not a good option in my opinion, it lasts much to long."

2 / 10
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23 Report
  • Kris
  • Taken for 2 to 5 years
  • June 18, 2019

"I have never felt truly "well" taking amitriptyline, but it made me feel better than being on nothing. My pain was reduced but not eliminated. However, it has not helped me reduce my brain fog, fatigue or insomnia. I believe that amitriptyline has made all of my other fibromyalgia symptoms, excluding pain, worse. Additionally, I had many side effects associated with taking amitriptyline. Most notably, I gained nearly 40 lbs. Since the extra weight made it hard to exercise and caused me to have more pain, I asked my doctor to reduce my dosage. Now I have more pain, less weight, slightly more energy and I am searching for a new medicine for my fibromyalgia."

3 / 10
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15 Report
  • Anonymous
  • Taken for less than 1 month
  • September 2, 2012

"Took this for leg pain that was from unknown cause, possibly pinched nerve or peripheral neuropathy. It seemed to help some with pain, maybe 30% reduction at 25mg dose. But I was sleeping 20 hours a day, real groggy when awake, and having severe stomach pains and constipation. I stopped after 2 weeks of this. I thought it was just side effects but my doctor diagnosed it as an allergic reaction."

3 / 10
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28 Report
  • epicric
  • November 26, 2015

"I've used this drug 2 times for pain and spasming due to focal distonia. First time was ten years ago and I had no response to it at all: not better, not negative. Then recently for focal dystonia and arthritis pain, and am rhappy with the results. I've been in constant creepy pain for a couple decades and for the first time, I have actually walked down the street, a couple times breathing freely and comfortable in my skin. I use 100 mg with tramadol, but the elivil is the closer. Weight gain and itching are side effects but if you start out knowing you'll crave tubs of ice cream you can discipline yourself and the food cravings become manageable instead of being a toss up between 50lbs overweight or pain."

9 / 10
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21 Report
  • Cazzzy
  • Taken for less than 1 month
  • June 18, 2016

"I'm taking 10 mg because I can't sleep with the pain I'm in. I have to say I don't feel drowsy on it but I do get to sleep wake up then easily go back to sleep. Last night I had a large glass of wine and took my tablet my became dry ( the norm) but when I woke after two hours sleep I'm in the dark and it was like objects were flying in the room coming towards me I kept my eyes closed and sat up opened them again and still had the objects coming towards me..'I woke my husband straight away as I was worried I'd do something. We looked online and said you should not take with alcohol.. I'm dreading tonight as I'm scared it will happen again.. Has anyone else had this ?"

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  • JJano
  • Taken for less than 1 month
  • January 30, 2021

Endep (amitriptyline) "Two days after taking Endep 10mg, 50% of my pain was gone. Lasted three days then the pain came back. Up the dose to 20mg and pain reduced again but legs feel twitchy and restless in the day. A weird feeling, usually happens at night. Will keep trying and see if it goes alway. Next step up to 30mg. So far it’s better than being in constant fibromyalgia pain 24/7. It did take 4-5 days to get use to sleep side effect. Within an hour of taking go straight to bed and try and sleep. Able to sleep with only waking once. Does make you tired in the morning but again it’s better than the pain. Worth a try. Good luck"

8 / 10
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10 Report
  • Anonymous
  • February 19, 2012

"This medicine made me so exhausted I would sleep at least 12 hours every night and I'd feel so tired all day I couldn't get anything done. And the two nights I couldn't take it when I was on it, I stayed up for over 24 hours with insomnia. It freaked me out that it would prevent me from sleeping if I didn't take it, so I got off of it quickly. It DID help some of the pain, but it wasn't worth it."

3 / 10
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25 Report
  • LeeDee
  • May 19, 2017

"I was only prescribed amitriptyline a week ago. I used it for the first time on Monday night and my experience was horrible. I felt like I had no control over my body, it really was a trip. I felt almost paranoid because of it and the dry mouth (which my doctor warned me about) was unpleasant. I made up my mind that I would rather go back to Xanax or lorazepam for my Depression and recently diagnosed PTSD."

1 / 10
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16 Report
  • Taking...
  • June 23, 2017

"I've haven't noticed any help in pain with this medication thus far. I am taking 25 mg the only thing I've noticed is that my sleep is actually worse I am sleeping less and staying more tired during the day even though I'm taking it at night. I'm really starting to think nothing is going to help my pain "

1 / 10
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15 Report
  • minni...
  • Taken for 6 months to 1 year
  • March 4, 2022

"This drug is amazing. It changed my life in days as I had fibromyalgia brought on by long term insomnia. I started with 10mg and within 2 days, my inflammation had drastically reduced, I was sleeping, and had no carpal tunnel pain that I had suffered with for months. I cannot recommend this highly enough. I rarely take it now - 4 years on - but occasionally take 10mg to break a spell of not sleeping"

10 / 10
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6 Report
  • cryst...
  • May 8, 2011

"I was so excited when my pain started to get better after slowly tapering up to 100mg nightly after trying countless medications that did not help. I have been on it for 5 months now...and have gained 30 lbs even while dieting...and the past couple weeks my pain had been coming back and I am lying restless in bed at night."

3 / 10
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22 Report
  • Mantis...
  • Taken for 1 to 6 months
  • July 24, 2020

"I took amitriptyline for fibromyalgia and hated it, it gave me side effect symptoms of awful brain fog, made me hallucinate when I took it, stopped me from dreaming, made me gain 60lbs in 2 months, and did more harm than good. All it did for me was increase the severity of my symptoms and add more side effects. I stopped taking it and my weight started to drop and the side effects wore off. I'm left with bad memory loss now."

1 / 10
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  • Joe
  • Taken for 1 to 6 months
  • April 1, 2022

"After trying several epileptic drugs , I ended up settling for dihydrocodeine . Months later several job changes I was pretty much loosing the ability to work and walk. I stopped taking that drug and ,went on to Amitriptyline , 5 weeks later , my legs have energy, I’m not falling a sleep in the day , it could be a fluke but I don’t think so . I feel alive and hopeful."

10 / 10
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  • Veron...
  • Taken for 1 to 2 years
  • March 8, 2023

"This drug gave me my life back. I had unexplained pain all over my body and lots of symptoms associated with nerves. I couldn't sleep at night and I was so depressed to the point of having suicidal thoughts. After having all possible tests done my rheumatologist put me on Amitriptyline (starting with 10mg). At first side effects were making me feel like a zombie so I stopped taking it (big mistake) after some time I started it again feeling absolutely hopeless. I slowly increased my dose to 30mg and I no longer have sleep issues in fact my sleep is amazing now. 90% of my fibromyalgia symptoms are gone now and I'm virtually pain-free. The only downsides to it are your appetite increases and you get constipation issues every now and then. This is an amazing drug but it takes many months for it to kick in properly."

10 / 10
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3 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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