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Amitriptyline for Fibromyalgia User Reviews (Page 2)

Amitriptyline has an average rating of 6.5 out of 10 from a total of 104 reviews for the off-label treatment of Fibromyalgia. 46% of reviewers reported a positive experience, while 27% reported a negative experience.

Reviews for Amitriptyline

  • Wot
  • Taken for 1 to 6 months
  • October 26, 2016

"I went from having horrific painsomnia and feeling like a zombie 24/7 and being really agitated by noise and light to having a regular sleep pattern which for sure helped me deal with pain and stress. I'm only up to 30mg a day and I've found coupled with pool therapy this treatment has been invaluable. Only annoying thing is that I get really bad dry mouth (but means I'm drinking more water) and I've totally lost my sex drive."

9 / 10
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50 Report
  • Lemmi...
  • November 5, 2013

Endep (amitriptyline) "I have been on Endep for Fibromyalgia for 10 years. At first the affect was awesome, for the first time in many years I slept properly and had hardly any pain. Over the years though, this has changed. I started off on 50mg per day and over the years had to have it increased to the maximum does of 150mg. Recently I have been having heart palpatations and an increased heart rate. My doctor has put it down to the extended time I have been on Endep at such a high rate. So now I am on a drug to lower my heart rate, which works well, but my doctor is getting me to try to cut down on the Endep with a view of going off it altogether and hopefully also going off the drug that I need to lower my heart rate. It's not working I'm in too much pain"

7 / 10
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62 Report
  • Anonymous
  • May 22, 2012

"I just started this medication for my fibromyalgia about 3 days ago. I'm already sleeping better, getting relief from my chronic migraines AND it has helped my irritable bowel syndrome. I know it's still too soon to tell but I really didn't expect results this soon. Hopefully things stay on the up and up. I have suffered from fibro for over 16 years now and have tried numerous meds."

7 / 10
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66 Report

Frequently asked questions

  • Jims
  • May 29, 2019

Elavil (amitriptyline) "Taking Elavil pills at bed time around 10 to 11pm. First pill made me sleep for two days. 2nd pill less tired but slept all day. 3rd pill slept all day. 4th to 7th pill less tired but no relief of pain, actually an increase of pain in lower back and tightness in shoulders and neck. Not sure If I'll take anymore! Other meds being used: Tizanidine, Armodafinil, Basaglar - long acting insulin (other diabetic meds make me sick) -lower back pain -muscle tightness -sweating - increased hot flashes -(I wish) fruit-like breath odor -increased hunger -loss of consciousness - lack of concentration, find myself just drifting off watching shows. I usually have a busy mind, even with brain fog, I usually have a show on while doing 2-3 other things. I have a high IQ and like to use it, but with this med it dumbs me down significantly."

1 / 10
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33 Report
  • Vicki...
  • Taken for 10 years or more
  • September 16, 2014

"I feel like a zombie if I don't get enough restorative sleep. I have been on 100 mg a day, but am on 75mg most of the time. I notice that most of the people that are not getting relief from the pain and insomnia are taking the smaller doses. I have been on it for probably 20 years. I can't tolerate most other medicines."

10 / 10
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54 Report

Are you taking this medicine?

  • denise...
  • Taken for 6 months to 1 year
  • August 23, 2012

"I take it for sleep. Started on a low dose and increased later. I am not on 75mg per day. It is not expensive and is an old medicine so side effects are well studied. Only issue is that if I miss one dose you can feel depressed. Sleep is a huge part to conquering this. I have noted a huge difference in my sleep and how I feel on a morning. I am better able to work as well. Brain coming back."

9 / 10
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61 Report
  • Guide...
  • December 12, 2013

"Just started on 10mg at night to help me sleep I have degenerative disk same symptoms as fibromyalgia. Sleeping better now, feel a bit better . Only my first week no side effects my GP told me to drink hot water everyday. "

10 / 10
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54 Report
  • Nickn...
  • Taken for 5 to 10 years
  • October 13, 2019

Endep (amitriptyline) "Wonder drug. I was in pain for fibromyalgai for years. Then I took 10 mg of Endep. I was better already next day, without any pain in 2 days. After some time, about 2 years, the pain was slowly coming back. My doctor increased the dosage to 25 mg. Again, it helped immediately. Now, I am away from home and my doctor, pain is getting unbearable. I don’t know what to do. Take two tablets a day? I will be soon home, but it is ruining my holiday. I can’t imagine my life without Endep."

10 / 10
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29 Report
  • AD2203
  • Taken for 1 to 6 months
  • February 26, 2020

"Elavil has been a game changer for me. I suffer from Major Depression, Anxiety, Fibromyalgia, Chronic Migraines and I have a rare recurring form of Viral Meningitis. I have been on multiple medications to tackle both nerve pain and depression/anxiety: Lexapro, Effexor, Cymbalta, Savella, Gabapentin, Zoloft. Sleep was difficult for me. I was up usually in pain from these ailments. When I stared taking Elavil, I'm able to feel like a normal person. I'm not overly stressed, I'm more "chill" at work and I don't feel as angry. Now for the nerve pain and migraines, there has been a slight reduction in the pain I feel but I'm still in pain."

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  • gigiboo
  • Taken for 6 months to 1 year
  • September 18, 2017

"I started it and noticed I slept well after first tablet. The 10mg works better for fibromyalgia on low dose apparently (10mg) but anyway I took it daily an hour or two before bed but it did take a good 4 months to get into my system and work on blocking out most of my pain and actually get to grips with my own personal experiences with this chronic condition. It worked really well on my migraines I get them occasionally if I eat food triggers wheat - dairy - msg amongst other triggers but not nearly as bad as before I started taking amitriptyline. I can honestly say its given me back my life and can plan ahead which I have never been able to do before. I gave it a 10/10. My side effects were dry mouth for few weeks and I watch my diet because it can increase your appetite"

10 / 10
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38 Report
  • Anonymous
  • April 4, 2011

Elavil (amitriptyline) "This medicine is a major player in my fibromyalgia. It helps me sleep through the night, because it reduces the pain at night. I went off it for a week and I never slept more then 2 hours continuously for that week. I give this medicine a thumbs up for that reason. It doesn't help at all for the pain I have ALL DAY. "

6 / 10
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63 Report
  • Anonymous
  • Taken for less than 1 month
  • July 15, 2012

"Last night was my first dose. Half of a amitriptyline 25mg tablet. I took it at quarter to midnight, but did not finally fall asleep until around 5AM. I slept for almost twelve hours. I guess I need to take it earlier if it doesn't knock me out like I expected. The light hurts my eyes today. I can't look out my window. Artificial light isn't as bad, but still hurts. Despite these problems, I feel more clear than I have in months. Maybe even years. Any pain that I have is very slight, so I'm thinking that's why my doctor wanted me to take ibuprofen with this - because it will actually be able to help with my pain now. This is only after my first dose, but I am pretty excited. I can move around the house again like a normal person!"

7 / 10
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57 Report
  • Apeke...
  • Taken for 2 to 5 years
  • March 8, 2016

"I love amitriptyline. I take 125mgs every night and my symptoms have been greatly reduced. I still have days where I don't walk so good but I have a lot more good days than bad. Before I started on this medication I wondered how I could live my life. I also get a great nights sleep. There are drawbacks for me. It has cut out a lot of my social life as I take it about 8pm. I don't have the sexual drive I used to but I am lucky enough to have a wife that understands how much better I am physically in other aspects of my life. Some nights I am not so bad but other nights I am ready for bed by 9:30. I don't have as much pain as I used to have, but I also have stenosis, scoliosis and osteoarthritis of the spine."

9 / 10
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  • Jenna
  • Taken for 2 to 5 years
  • September 21, 2016

"I started Amitriptyline for Fibromyalgia, with hopes that it would also help with depression & anxiety. My max dose so far is 40mgs @ bedtime. Initially, it was extremely sedating, but less so as time went on, & when I started taking Wellbutrin for fatigue, I had no residual sedation or daytime sleepiness at all. Ami was a life saver to me in regards to pain relief. As for depression & anxiety, it wasn't helpful until I combined it with Wellbutrin. I would highly recommend the combo for Fibro fog/fatigue/pain/anxiety/depression. It's like taking an SNRI without the side effects! I increase by 10mgs as needed when my pain begins breaking through. I also found if I'm really stressed or anxious during the day & take 10mgs, it is very calming."

8 / 10
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39 Report
  • Shar
  • Taken for 5 to 10 years
  • January 25, 2020

"Miracle drug for me is amitriptyline for fibro. My fibro symptoms appeared violently in 2009 and it took 5 years of repeated Dr visits and being written off as a hyperchondriac before I was diagnosed and put on Endep. After 5 years of horrific pain, no sleep while having to work full time just about was the end me, I became pain free. After 3 months the pain slowly came back but never to the level it was. I booster the pain relief with Mersyndal at night."

10 / 10
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25 Report
  • Anonymous
  • Taken for 5 to 10 years
  • November 7, 2012

"I have had Fibro for 10 years (7 years since diagnosis). Amitriptyline has been the only constant help. All other medications have had no effect. Amitriptyline almost eliminates back pain (hasn't helped any other muscle pains. A dose of 75mg taken before bed gives me a full night's sleep. Side effects of weight gain, dry mouth and urinary retention just have to be managed until I can find anything better."

6 / 10
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51 Report
  • Mothe...
  • March 28, 2016

"This medicine has really helped me to sleep. My pain has gone down including migraines. I am still very stiff in the morning and sometimes I have weak legs. Only two side affects I've noticed, dry mouth and sleepy in the morning if I take the meds too late. But still pretty happy with the meds."

9 / 10
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38 Report
  • Daano
  • Taken for less than 1 month
  • August 21, 2019

"I was prescribed amitryptiline for my fibromyalgia and within a very short time my symptoms worsened considerably. I was severely fogged, and in more pain than before - restless legs, overheating, headaches and exhausted 90% of the time - none of which I had before. A different doctor told me to stop taking it as it was poisoning my system. The symptoms haven't eased even though I don't take them anymore. I can't enjoy my young grandchildren, which is heart breaking."

1 / 10
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25 Report
  • Cattius...
  • Taken for 2 to 5 years
  • September 29, 2017

"I have been taking 20mg at night for a couple of years and can't praise it highly enough. I had terrible muscle cramps and twitching and constant burning pain in my arms and legs, within a few days of starting the drug, my symptoms began to ease. The twitching is now only very mild, the pain is 2 out of 10 and the spasms non existent! Magic."

10 / 10
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32 Report
  • Anonymous
  • June 28, 2011

"I've had Fibromyalgia for a long, very long time. I was diagnosed in the year of 1995, I also found out that due to the fibromyalgia that I have weak bones, and taking medicines increased my already there asthma. What worked for me was the amitriptyline 25mg 1 a day also a great medicine called Tolmetin Sodium 600mg, 3 x's a day. I've been taking these two medicines and have been able to work 40 hours a week with no side effects. I walk over 4 miles, hardly any pain and do strength training without having to take more medications. If you are having lots of pain due to fibromyalgia you might want to talk to your doctor and find out if you can take these two medicines together. All in all I was hugged and it didn't hurt for the first time in eight years."

9 / 10
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52 Report
  • Senan
  • Taken for 10 years or more
  • August 3, 2017

"I am using trypiyizole 10 mg for around 12 years to treat fibromylagia and I feel very happy With the improvement .I can say that it is a miracle drug ,also it did not cause any side effects Though it is an old generation drug but it is much effective ."

10 / 10
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29 Report
  • Jenny...
  • September 11, 2015

Elavil (amitriptyline) "I haven't started this drug yet, but am suppose to today, I'm scared to take it from reading everyone's reviews cause I'm a tired person and have IBS so any change can make me really sleepy or feel sick, I'm really sleepy. I'm 31 with 2 kids. I don't want to be more tired or feel like a zombie cause half the time I do anyways. I'm crying cause I'm so scared to take this drug cause the side effects seem so much and those side effects always affect me. I will try it so my doctor can't hound me about taking it. I really don't wanna lose my thoughts cause I have a bad memory as is. But what can you do when you have to be a lab rat for your doctor, not happy!"

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34 Report
  • red
  • May 25, 2010

Elavil (amitriptyline) "I first started out at 50mg of Elavil almost 2 years ago. It was like instant heaven! I am a horrible insomniac and with Elavil I was getting good quality sleep and woke up feeling rested. I was also on Lyrica at the time. For a while both of them together had me feeling a lot better. Unfortunately I have a very high tolerance to any medicine. I am now at 150mg Elavil. I can't imagine going any higher yet my pain is increasing so I don't know what will happen when I totally max out at this level. I no longer take Lyrica as I became tolerant. Savella seems to help with fibromyalgia fog but it doesn't touch my pain. Give it a try. "

9 / 10
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47 Report
  • Honey...
  • Taken for less than 1 month
  • September 30, 2017

"Started taking 20mg before bed. I have fibromyalgia. I also take 150mg of lyrica a day to make it threw an 8 hour shift. Without lyrica I wouldn't be able to work at all. I would wake up with my hair being a total mess like I was sleeping restless. My doctor said to start this at 20mg before bed and if that dose doesn't help increase by 10mg until I get to a level that works. First couple nights have been wonderful. But I have been waking up at 6am both days and can't go back to sleep. I feel rested and alot less morning pain. Doctor is hoping I can go off lyrica. Lyrica is causing me to feel high. I get 8-9 hours relief with lyrica and then my pain comes back. I have gained about 10lbs while on lyrica but at least I can work."

7 / 10
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25 Report
  • Jasper
  • January 17, 2011

Elavil (amitriptyline) "I was just diagnosed with Fibromyalgia, was beginning to feel like I am losing my mind. I am 29 yrs old and some days can barely walk I hurt so bad. I have been on Elavil for headaches 10 mg is all I can handle as it knocks me out. It helps to prevent the headaches but I hurt so bad still. Thankful to be rid of headaches but wish the doctor would help!"

2 / 10
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42 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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