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Amitriptyline for Anxiety and Stress User Reviews (Page 5)

Amitriptyline has an average rating of 7.5 out of 10 from a total of 173 reviews for the off-label treatment of Anxiety and Stress. 68% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Amitriptyline

  • Jiga
  • Taken for 6 months to 1 year
  • October 5, 2017

"After one of the worst years of my life I developed anxiety, was prescribed Endep 25mg, progressed to 50mg then 100mg. Side effects were full on and included but were not limited to dizziness, short term memory loss, black outs (momentary but scary), nightmares, indigestion, incredible tiredness (cloudy head, fuzziness), dry mouth and one of the deepest most horrible depressive states I have ever been in which included suicide thoughts , but hey, I didn't have anxiety! THIS IS A WARNING, if you develop suicidal thoughts while taking this drug see a doctor immediately!"

1 / 10
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38 Report
  • Anne...
  • July 23, 2016

"Took 10 mg for the first time last night for insomnia. To my great surprise, today it seemed to help with both muscle achyness & with anxiety. I slept all day (& needed it), but I suspect that won't be a big issue once I take this med more regularly (which was the case when I was on mirtazapine/Remeron)."

8 / 10
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42 Report
  • lilrif
  • Taken for 2 to 5 years
  • April 1, 2013

"I've been on it for 4 years and it does much more for my bipolar and extreme anxiety, then it does for my pain. I am now taking 50mg morning and 100mg evening. The new increase at night does seem to make my sleep a lot less uncomfortable and broken up."

7 / 10
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54 Report

Frequently asked questions

  • Meemo
  • Taken for 1 to 6 months
  • March 14, 2019

"I was prescribed amitript 10mg/day for anxiety. Previous SSRIs had left me with constant shakes and sleep deprived. Amitriptyline did help with was my neck pain and my sleep pattern returned to normal which was great. Unfortunately even at the lowest dose of 10mgs I was unable to function. I felt like a zombie and my coordination was shot to pieces and I was breathless doing the smallest of physical activities. I cut to 5mgs because the pain relief to my neck was such a boon, but the negative side effects were still to great to continue a normal life. Shaking, woolly headed, forgetful and still an underlying anxiety that erupted over the smallest of issues. Useless for my anxiety because of my sensitivity to the drug, but great for pain relief. I tried it for 4 weeks before being switched to a beta blocker."

3 / 10
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  • Helped...
  • Taken for 1 to 6 months
  • June 23, 2022

"I'm on amitriptyline for a few different conditions combined, primarily for anxiety and depression but it also helps with migraines and chronic pain, all of which I have. The reviews that say it takes a while to work, i.e. a few weeks to a month, kept me hopeful and I have taken it religiously around the same time every night. My anxiety has definitely improved, I feel like this must be what normal people feel like on a day to day basis. I used to suffer from tightening in the chest/chest pain almost constantly, racing thoughts, and a lot of other unpleasant anxiety symptoms and now I notice a HUGE difference especially in that tight/painful chest feeling from my anxiety, it's just gone. I also no longer have any thoughts about ending things, which I was feeling previously. My pain has improved as well. The only side effect I am not very fond of is the drowsiness but I am willing to deal with it for the huge reduction in anxiety I feel."

9 / 10
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Are you taking this medicine?

  • Sherry
  • Taken for less than 1 month
  • August 16, 2021

"I have to say this is the only antidepressant that has so far works for me in on 25 mg for sleep and stress. I take at night took few days to help with sleep, but now I've been sleeping great, and few side effects nothing major. I can't take Lexapro and this is another class of antidepressants, believe me if I can take it anyone can, it's the only one I haven't stopped. It hasn't been 6 weeks yet to get full benefits, but my tension headaches I woke up to every morning are gone, give it go and don't look back ❤️❤️❤️❤️❤️❤️❤️"

10 / 10
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  • Anonymous
  • September 12, 2021

"I just started this medication again since my panic attacks and anxiety have gotten so worst ! This medication is a life saver ! I had 0 side effects just a dry mouth in the morning but that’s it - I highly recommend you take amitriptyline. I’ve tried other medication like lexopro and it made me really sick and suicidal never again will I go back to those other antidepressants."

10 / 10
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17 Report
  • Sarja
  • Taken for 6 months to 1 year
  • April 23, 2022

"I found this really helpful for anxiety and depression and ADHD I tried other types like citalopram but found this was the only one suitable for me as I have IBS too and most would really make it flare up. I sleep well and am in a more positive mood through the day without feeling "out of it " I can function really well for work and any other activities"

8 / 10
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14 Report
  • Kate
  • Taken for 1 to 2 years
  • July 6, 2023

"Amitriptyline has helped me far better than any other drug for stress, anxiety, and insomnia. My anxiety led to insomnia, and those two led to seizures. In a way, I guess you could say it's helped with those too. I don't have them if I can sleep."

10 / 10
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7 Report
  • Anonymous
  • Taken for 10 years or more
  • October 14, 2017

"I have been on this drug for more than 30 years. I feel that it helps with my depression but there are many side effects that I do NOT like. My mouth is always dry and my tongue is always moving. Many family pictures have my tongue sticking out."

8 / 10
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32 Report
  • Nikki
  • January 24, 2020

"My 8 year old son has social issues and uses aggression and anger to express himself. After 12 months of tests with a Paediatric doctor we have found out my son has mild case of ADHD. He doesn’t eat either all his foods are white (pasta, bread, chips and nuggets) my doctor prescribed me this medication on the 7th Jan only 10mg a day. I haven’t seen a difference yet. How long does it take to start working. Only thing he wakes up happy not angry like before"

8 / 10
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23 Report
  • Migra...
  • Taken for 1 to 6 months
  • April 1, 2023

"I started 10 mg of this 5 weeks ago before bed. I have noticed an improvement in talking bout stressful subjects and giving me more motivation to do my hobbies and I am loving living again. Amazing drug."

10 / 10
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8 Report
  • Palacio
  • April 13, 2016

"Was given this medication for migraines, worst mistake ever, I had bad thoughts about myself, had panic attacks, lost control of myself. Only took it for two nights. Please read the paper because I didn't, only after. Never again. Good luck to everyone else x"

1 / 10
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33 Report
  • Stres...
  • Taken for less than 1 month
  • August 5, 2021

"This drug helps me so much, I have tinnitus and crazy stress with anxiety. It calms me down and really doesn't have the awful side effects I get from SSRI's, I was actually allergic to zoloft and it made everything worse, even after 2 weeks. But 10 days on this drug and I'm beginning to see subtle improvement, and I haven't had a panic attack since I started. I take propanolol and klonopin still but I think the need for those will diminish soon. I used to take this same drug a few years back and it helped me so much, hoping for the same results. Started on 50mg and hopefully that's where I can stay, but I'm not scared if I need to up my dose, unlike zoloft which scared me everytime I'd up the dose, along with the scary side effects. No real side effects from this, at least none that are noticeable or annoying."

10 / 10
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  • Anonymous
  • January 21, 2017

"Try one of the newer meds out there first. GP prescribed me this for anxiety and I blindly took it thinking doc knows best, went to a Pdoc a few months later and she was mortified that I was prescribed this. I have been weaning off since and finally at 0mgs for past few days, but all the weaning side effects have been terrible. I feel nauseous all day and cannot sleep at all, and have chest pains,with constantly feeling in a fog. Do yourself a favor and trust how far medicine has come since they made this drug and try one from this era first"

1 / 10
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29 Report
  • Chriso
  • October 22, 2016

Endep (amitriptyline) "Been taking it for 6 years initially for depression then anxiety and stress and it's one of the worst things to happen to me. Constant eczema where my skins gets very itchy and sore that I have scars all over, constipation is probably the worst as I've had periods of vomiting to stomach being sore and bloated, blurred vision, it's addictive contrary to what doctors say as I have been trying to get off it for 2 years slowly and been admitted to hospital twice in that time for substance abuse relating to endep. Doctors can't understand why I have been on it for so long. Take mine at night as you get drowsy of a day on higher than 50mg (most I taken was 75mg) now on 10mg and still get constipation."

1 / 10
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  • GuyInSa
  • Taken for 6 months to 1 year
  • November 11, 2016

"Nothing has worked for me for anxiety, depression, or insomnia. Add this to the list. I wish I could find something that works. My doc put me on 50mg of this in the morning and before bed, along with 1 & 1/2 1.5mg klonipin 3x a day and 2mg Xanax as needed. I was also given lexapro for depression. It didn't help at all. Caused sleeplessness, restlessness, worsened insomnia, weight gain and bloating, ED, and gynocemastia. Not sure which meds caused which, but I was also on nexium, water pills, and lisinipril. Got off all meds as fast as I could and am still suffering from stage 2 hypertension, depression, anxiety, SAD, insomnia, and GERD without meds. Life is rough, but at least I'm not dealing with side effects."

1 / 10
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  • Auske...
  • Taken for less than 1 month
  • February 24, 2016

"I took this medicine for anxiety and panick attacks. After suffering for several months trying all sorts of medication. It was this old school medicine that gave me hope that i can actually recover. It improves my general health condition. But i found it difficult to wake up from sleep while i was still on this medication.It really helps but did not address the symptoms permanently."

6 / 10
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  • mrhappy
  • July 1, 2009

"Have previously been on this medication 6 years ago. In between have been on SSRI's and venlafaxine (the latter being a nightmare to withdraw from). Now after a year of medication free I'm back on amitriptyline at my request due to mega anxiety and stress issues (not my doctor's first choice), also currently taking Ramipril and diltiazem for high blood pressure - so far early days and am suffering the main side effect of tiredness but managed a 2.5 mile jog last night. It's early days and I am hoping this will work as well as it did in the past."

8 / 10
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45 Report
  • Sleep...
  • April 29, 2019

"Was prescribed 5mg every night which would help my anxiety and a reduction in migraine which caused me to have dizziness. One week after it greatly helped in my migraines. However stopped due to having twitches in thumb. Not sure if the trade is worth it. But it helps in your sleep and migraines."

3 / 10
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20 Report
  • Bosco
  • Taken for 2 to 5 years
  • October 9, 2021

"This medication works quickly and sufficiently for me, I take one 50 mg tablet at bedtime and it allows for better sleep, less waking up. Amitriptyline also helps calm my nerves during the day, it's long acting relief with very little drowsy aspect. Taken at night, by morning I have slept better and wake more mellow and good to go during the day."

10 / 10
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12 Report
  • Re Nash
  • June 11, 2018

"I went to a neurologist for trouble with anxiety as I was going through a number of issues including a break up. She prescribed 10 mg of amitriptyline. The side effects seemed quite scary so didn’t take it the first week. Then one night decided to take it. It knocked me out and had trouble getting up the next day. I had a boat to catch and barely made it. At my destination, at the hotel straight to bed for a few hours. So I decided to not take any more"

2 / 10
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22 Report
  • Caused...
  • Taken for less than 1 month
  • October 21, 2016

"Was prescribed 10 mg for cystitis 1 pill one hour before bed time. After taking the second pill I got severe anxiety attack which led me down on the road of developing GAD and panic disorder. I did not know what was happening to me why I felt so hyper and kind of sick, had heart palpitations, like I had a ton of coffee. The morning I still felt severe anxiety, called the doctor, made appointments to figure it out what is wrong with me. I started loosing weight because I lost my appetite and I guess all the worry created more worries and eventually panic attacks. It may work for others but be very careful when trying it the first time."

1 / 10
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24 Report
  • Buzzy
  • Taken for 10 years or more
  • August 23, 2021

"I was on this medication for over 25 years. It is a bad drug. It might help you when you are on it but taper off of it and be off of it and you will suffer as I have. Three months off it and still having terrible insomnia, panic attacks, etc. Don't start this drug you will be better off in the long run."

1 / 10
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  • Taurus
  • Taken for 10 years or more
  • November 10, 2021

"I have been on amitriptyline for 15 years. It has really helped me except at age 73 I feel it's causing extreme dry eye. I dread having to come off it, as I feel well on it I am also on seroxat for 15 years. Has anybody else experienced dry eye with those drugs. Amitriptyline 25 mgs. I take at night. ,and seroxat 20 mgs in am. Would love to know. Thanks"

8 / 10
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10 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.