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Sevelamer

Pronunciation

Generic Name: sevelamer (se-VEL-a-mer)
Brand Name: Examples include Renagel and Renvela

Sevelamer is used for:

Reducing the amount of phosphorus in the blood in patients with chronic kidney disease who are on dialysis.

Sevelamer is a phosphate binder. It binds with phosphate in the digestive tract, which decreases the amount of phosphate absorbed into the body.

Do NOT use sevelamer if:

  • you are allergic to any ingredient in sevelamer
  • you have a blockage of your bowels

Contact your doctor or health care provider right away if any of these apply to you.

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Before using sevelamer:

Some medical conditions may interact with sevelamer. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have difficulty swallowing or certain stomach or bowel problems (eg, severe constipation), or if you have had stomach or bowel surgery
  • if you have low blood phosphate levels
  • if you take medicines for irregular heartbeat, seizures, or thyroid problems

Some MEDICINES MAY INTERACT with sevelamer. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Ciprofloxacin because its effectiveness may be decreased by sevelamer

This may not be a complete list of all interactions that may occur. Ask your health care provider if sevelamer may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use sevelamer:

Use sevelamer as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take sevelamer by mouth with food.
  • Swallow sevelamer whole. Do not break, crush, or chew before swallowing.
  • Sevelamer may bind with other medicines, reducing the amount your body can absorb and use. If you are taking other medicines, your doctor may want you to take them 1 hour before or 3 hours after taking sevelamer. Contact your doctor if you have questions about when to take your dose.
  • Continue to take sevelamer even if you feel well. Do not miss any doses.
  • If you miss a dose of sevelamer, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use sevelamer.

Important safety information:

  • Sevelamer may reduce certain vitamins in your body. Check with your doctor about whether or not you should take a vitamin supplement while you take sevelamer.
  • Follow the diet program given to you by your health care provider.
  • Lab tests, including calcium, bicarbonate, phosphate, and chloride blood levels, may be performed while you use sevelamer. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Sevelamer should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using sevelamer while you are pregnant. It is not known if sevelamer is found in breast milk. If you are or will be breast-feeding while you use sevelamer, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of sevelamer:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; gas; indigestion; mild stomach pain; nausea; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); severe or persistent constipation or stomach pain; trouble swallowing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of sevelamer:

Store sevelamer at 77 degrees F (25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is allowed. Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Do not use after the expiration date. Keep sevelamer out of the reach of children and away from pets.

General information:

  • If you have any questions about sevelamer, please talk with your doctor, pharmacist, or other health care provider.
  • Sevelamer is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take sevelamer or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about sevelamer. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to sevelamer. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using sevelamer.

Issue Date: November 5, 2014
Database Edition 14.4.1.002
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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