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lanthanum carbonate

Generic Name: lanthanum carbonate (LAN than um CAR bo nayt)
Brand Name: Fosrenol

What is lanthanum carbonate?

Lanthanum prevents the body from absorbing phosphate, allowing it to be removed from the body.

Lanthanum carbonate is used to lower phosphate levels in patients with end stage kidney disease. High levels of phosphate can make it hard for your body to absorb calcium, which can cause serious medical problems.

Lanthanum carbonate may also be used for purposes not listed in this medication guide.

What is the most important information I should know about lanthanum carbonate?

You should not use lanthanum carbonate if you have a bowel obstruction or severe constipation.

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What should I discuss with my healthcare provider before taking lanthanum carbonate?

You should not use lanthanum carbonate if you are allergic to it, or if you have:

  • a bowel obstruction or severe constipation.

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, tell the doctor ahead of time that you are using lanthanum carbonate.

To make sure lanthanum carbonate is safe for you, tell your doctor if you have:

  • a stomach ulcer;

  • ulcerative colitis;

  • Crohn's disease;

  • diabetes;

  • problems with your teeth;

  • any type of bowel obstruction;

  • a history of colon cancer or intestinal surgery; or

  • if you take any medicines that can cause constipation.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether lanthanum carbonate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

How should I take lanthanum carbonate?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Take lanthanum carbonate with food or immediately after eating.

The chewable tablet should be chewed completely before you swallow it. Do not swallow whole.

Sprinkle the oral powder into a small amount of applesauce or other soft food (oral powder will not dissolve in liquid). Swallow right away without chewing. Do not save the mixture for later use.

While using lanthanum carbonate, you may need frequent blood tests.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking lanthanum carbonate?

Lanthanum carbonate can make it harder for your body to absorb other medicines you take by mouth.

  • If you also take thyroid medication, take it at least 2 hours before or 2 hours after you take lanthanum carbonate.

  • If you take an antibiotic such as ciprofloxacin (Cipro) or levofloxacin (Levaquin), take the antibiotic at least 1 hour before or 4 hours after you take lanthanum carbonate.

  • Avoid taking an antacid within 2 hours before or 2 hours after you take lanthanum carbonate.

Lanthanum carbonate side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe constipation; or

  • severe stomach cramps.

Common side effects may include:

  • upset stomach, stomach pain, nausea, vomiting;

  • constipation;

  • itching, rash; or

  • tooth injury while chewing a lanthanum carbonate tablet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

Lanthanum carbonate dosing information

Usual Adult Dose for Hyperphosphatemia of Renal Failure:

Initial dose: 1500 mg orally daily; take in divided doses with meals
Titrate in increments of 750 mg/day every 2 to 3 weeks until an acceptable serum phosphate level is reached
Maximum dose: 4500 mg/day

Comments: Most patients will require daily doses between 1500 and 3000 mg to reduce plasma phosphate levels to less than 6 mg/dL.

Use: To reduce serum phosphate levels in patients with end stage renal disease.

What other drugs will affect lanthanum carbonate?

Other drugs may interact with lanthanum carbonate, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Where can I get more information?

  • Your pharmacist can provide more information about lanthanum carbonate.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 4.02. Revision Date: 2015-05-08, 11:13:53 AM.

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