Generic Name: pancrelipase (PAN-kree-LYE-pase)
Brand Name: Viokace
Pancrelipase is used for:
Improving food digestion in patients who cannot digest food properly because they have a pancreas problem (exocrine pancreatic insufficiency) caused by inflammation of the pancreas that lasts a long time (chronic pancreatitis) or the removal of the pancreas. It is used along with a proton pump inhibitor (PPI) (eg, omeprazole). It may also be used for other conditions as determined by your doctor.
Pancrelipase is a digestive enzyme combination. It works by helping the body to digest protein, starch, and fat.
Do NOT use pancrelipase if:
- you are allergic to any ingredient in pancrelipase
Contact your doctor or health care provider right away if any of these apply to you.
Before using pancrelipase:
Some medical conditions may interact with pancrelipase. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances (including pork proteins)
- if you have gout or high uric acid levels
- if you have a history of kidney problems, high blood sugar, or diabetes
- if you have a history of pancreas problems, stomach or bowel problems (eg, blockage, scarring, thickening, short bowel syndrome, Crohn disease), or if you have had bowel surgery
- if you are lactose intolerant
- if you have trouble swallowing tablets
Some MEDICINES MAY INTERACT with pancrelipase. However, no specific interactions with pancrelipase are known at this time.
Ask your health care provider if pancrelipase may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use pancrelipase:
Use pancrelipase as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Pancrelipase comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get pancrelipase refilled.
- Take pancrelipase by mouth with each meal or a snack as directed by your doctor. Be sure not to take more tablets in a day than the number your doctor tells you to take.
- Swallow pancrelipase whole with enough liquid to swallow it completely. Do not break, crush, chew, or hold pancrelipase in your mouth before swallowing. Doing so may increase the risk of mouth or tongue irritation from pancrelipase. Contact your doctor if you experience mouth or tongue irritation while taking pancrelipase.
- Pancrelipase is used along with another medicine called a proton pump inhibitor (PPI) (eg, omeprazole). Be sure to take the PPI as directed by your doctor.
- If you miss a dose of pancrelipase, skip the missed dose and take the next dose with the next meal or snack as directed. Do not take 2 doses at once or take a dose without a snack or a meal.
Ask your health care provider any questions you may have about how to use pancrelipase.
Important safety information:
- Follow the dietary guidelines given to you by your health care provider.
- Do NOT take more or less than the recommended dose without checking with your doctor.
- Do not switch between pancrelipase and another pancreatic enzyme medicine without first checking with your doctor.
- Pancrelipase may increase the risk of developing a rare, serious condition called fibrosing colonopathy. When this occurs, it is usually with high doses over a long period of time. It has been most commonly reported in children with cystic fibrosis. Contact your doctor right away if you experience unusual or severe nausea, vomiting, or stomach pain; stomach bloating; or severe or persistent loose stools, constipation, or diarrhea.
- Pancrelipase comes from pork (pig) pancreas tissue. There is an extremely rare risk of developing a viral disease from this product. No cases of viral disease from pork pancreas products have been identified.
- Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Pancrelipase is not approved for use in CHILDREN. Use of pancrelipase in children may result in poor nutrition and slowing of growth. Other pancreatic enzyme dosage forms (eg, delayed release, enteric coated) may be preferred for use in children. Discuss any questions or concerns with your doctor.
- PREGNANCY and BREAST-FEEDING: It is not known if pancrelipase can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using pancrelipase while you are pregnant. It is not known if pancrelipase is found in breast milk. If you are or will be breast-feeding while you use pancrelipase, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of pancrelipase:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Anal itching; gas; headache; stomach pain.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); mouth irritation; painful, swollen joints; severe or persistent loose stools, diarrhea, or constipation; severe or unusual nausea, vomiting, or stomach pain; stomach bloating.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of pancrelipase:
Store pancrelipase at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store in the original container with the lid tightly closed and away from heat, moisture, and light. Do not remove any moisture control packs that may come in the bottle. Do not store in the bathroom. Keep pancrelipase out of the reach of children and away from pets.
- If you have any questions about pancrelipase, please talk with your doctor, pharmacist, or other health care provider.
- Pancrelipase is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take pancrelipase or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pancrelipase. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pancrelipase. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pancrelipase.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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