Consumer Drug Information

Clindamycin/
Benzoyl Peroxide Gel

Generic Name: Clindamycin/Benzoyl Peroxide Gel with Cleanser (KLIN-da-MYE-sin/BEN-zoe-il per-OX-ide)
Brand Name: Duac CS Kit

Clindamycin/Benzoyl Peroxide Gel is used for:

Treating severe acne.

Clindamycin/Benzoyl Peroxide Gel is an antibiotic and drying agent combination. It works by killing the bacteria associated with acne.

Do NOT use Clindamycin/Benzoyl Peroxide Gel if:

you are allergic to any ingredient in Clindamycin/Benzoyl Peroxide Gel or to lincomycin
you have a history of Crohn disease, severe stomach or bowel problems (eg, ulcerative colitis, regional enteritis, pseudomembranous colitis), or stomach or bowel inflammation caused by antibiotic use
you are using products that contain erythromycin

Contact your doctor or health care provider right away if any of these apply to you.

Before using Clindamycin/Benzoyl Peroxide Gel:

Some medical conditions may interact with Clindamycin/Benzoyl Peroxide Gel. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have stomach or bowel problems
if you are using other medicines on the skin

Some MEDICINES MAY INTERACT with Clindamycin/Benzoyl Peroxide Gel. Because little, if any, of Clindamycin/Benzoyl Peroxide Gel is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Clindamycin/Benzoyl Peroxide Gel may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Clindamycin/Benzoyl Peroxide Gel:

Use Clindamycin/Benzoyl Peroxide Gel as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Use Clindamycin/Benzoyl Peroxide Gel on a regular schedule to get the most benefit from it.
Before applying Clindamycin/Benzoyl Peroxide Gel to the affected areas, gently wash the skin with the soap-free cleanser lotion. Rinse with warm water and pat dry. Apply a thin film of medicine to the affected skin and rub in as directed by your doctor.
Wash your hands immediately after using Clindamycin/Benzoyl Peroxide Gel.
Continue to use Clindamycin/Benzoyl Peroxide Gel even if your condition improves. Do not miss any doses.
If you miss a dose of Clindamycin/Benzoyl Peroxide Gel, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Clindamycin/Benzoyl Peroxide Gel.

Important safety information:

Clindamycin/Benzoyl Peroxide Gel is for external use only. Avoid contact with the eyes, nose, mouth, and other mucous membranes. If you get Clindamycin/Benzoyl Peroxide Gel in your eyes, rinse them right away with cool water.
Clindamycin/Benzoyl Peroxide Gel may bleach hair or colored fabric. Avoid getting Clindamycin/Benzoyl Peroxide Gel in your hair or on your clothes.
Clindamycin/Benzoyl Peroxide Gel may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Clindamycin/Benzoyl Peroxide Gel. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
If your symptoms do not get better or if they get worse, check with your doctor.
Talk with your doctor before you use any other topical acne medicines or cleansers on your skin.
Do not use Clindamycin/Benzoyl Peroxide Gel for other conditions at a later time.
Tell your doctor or dentist that you take Clindamycin/Benzoyl Peroxide Gel before you receive any medical or dental care, emergency care, or surgery.
Long-term or repeated use of Clindamycin/Benzoyl Peroxide Gel may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
Be sure to use Clindamycin/Benzoyl Peroxide Gel for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
If severe diarrhea, stomach pain or cramping, or bloody stools develop during treatment or within several months after treatment with Clindamycin/Benzoyl Peroxide Gel, check with your doctor or pharmacist right away. Do not treat it without first checking with your doctor.
Clindamycin/Benzoyl Peroxide Gel should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.
PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Clindamycin/Benzoyl Peroxide Gel while you are pregnant. It is not known if Clindamycin/Benzoyl Peroxide Gel is found in breast milk after topical use. Do not breast-feed while using Clindamycin/Benzoyl Peroxide Gel.

Possible side effects of Clindamycin/Benzoyl Peroxide Gel:

All medicines may cause side effects, but many people have no, or minor side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning, dryness, or peeling of the skin.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; severe burning, dryness, or peeling of the skin; severe or persistent diarrhea; stomach cramps or pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Clindamycin/Benzoyl Peroxide Gel may be harmful if swallowed.

Proper storage of Clindamycin/Benzoyl Peroxide Gel:

Store Clindamycin/Benzoyl Peroxide Gel at 77 degrees F (25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep tightly closed. Throw away any unused portion after 2 months. Keep Clindamycin/Benzoyl Peroxide Gel out of the reach of children and away from pets.

General information:

If you have any questions about Clindamycin/Benzoyl Peroxide Gel, please talk with your doctor, pharmacist, or other health care provider.
Clindamycin/Benzoyl Peroxide Gel is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Clindamycin/Benzoyl Peroxide Gel. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: September 3, 2008

Database Edition 08.3.1.003