Clindamycin Pregnancy and Breastfeeding Warnings
Clindamycin Pregnancy Warnings
The results of a study have suggested that early second trimester treatment of bacterial vaginosis and abnormal vaginal flora with oral clindamycin may reduce the incidence of preterm delivery and late miscarriage (n=485).
Clindamycin has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. However, clindamycin has been used during pregnancy and labor and delivery without adverse effects in the fetus or neonate. Clindamycin is only recommended for use during pregnancy when benefit outweighs risk.
Clindamycin Breastfeeding Warnings
Clindamycin is excreted into human milk. Concentrations of 0.7 to 3.8 mcg/mL have been reported. Adverse gastrointestinal effects have been reported in one nursing infant exposed to multiple drugs including clindamycin; however, the exact cause of these effects is unknown. The manufacturer recommends that due to the potential for adverse effects in neonates, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.