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Clindamycin Pregnancy and Breastfeeding Warnings

Clindamycin is also known as: Cleocin, Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate

Clindamycin Pregnancy Warnings

The results of a study have suggested that early second trimester treatment of bacterial vaginosis and abnormal vaginal flora with oral clindamycin may reduce the incidence of preterm delivery and late miscarriage (n=485).

Clindamycin has been assigned to pregnancy category B by the FDA. Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. However, clindamycin has been used during pregnancy and labor and delivery without adverse effects in the fetus or neonate. Clindamycin is only recommended for use during pregnancy when benefit outweighs risk.

Clindamycin Breastfeeding Warnings

Clindamycin is excreted into human milk. Concentrations of 0.7 to 3.8 mcg/mL have been reported. Adverse gastrointestinal effects have been reported in one nursing infant exposed to multiple drugs including clindamycin; however, the exact cause of these effects is unknown. The manufacturer recommends that due to the potential for adverse effects in neonates, a decision should be made to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.

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