protease delayed-release capsules
Generic Name: amylase/lipase/protease (a-mah-LASE/LYE-pase/PRO-tee-ase)
Brand Name: Examples include Creon 10 and Pancron 10
Amylase/lipase/protease delayed-release capsules is used for:
Improving food digestion in patients who cannot digest food properly because they have a pancreas problem (exocrine pancreatic insufficiency) caused by cystic fibrosis or certain other conditions. It may also be used for other conditions as determined by your doctor.
Amylase/lipase/protease delayed-release capsules is a digestive enzyme combination. It works by helping the body to digest protein, starch, and fat.
Do NOT use amylase/lipase/protease delayed-release capsules if:
- you are allergic to any ingredient in amylase/lipase/protease delayed-release capsules
Contact your doctor or health care provider right away if any of these apply to you.
Before using amylase/lipase/protease delayed-release capsules:
Some medical conditions may interact with amylase/lipase/protease delayed-release capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances (including pork proteins)
- if you have gout or high uric acid levels
- if you have a history of kidney problems, high blood sugar levels, or diabetes
- if you have a history of pancreas problems, stomach or bowel problems (eg, blockage, scarring or thickening, Crohn disease, short bowel syndrome), or if you have had bowel surgery
- if you have trouble swallowing capsules
Some MEDICINES MAY INTERACT with amylase/lipase/protease delayed-release capsules. However, no specific interactions with amylase/lipase/protease delayed-release capsules are known at this time.
Ask your health care provider if amylase/lipase/protease delayed-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use amylase/lipase/protease delayed-release capsules:
Use amylase/lipase/protease delayed-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take amylase/lipase/protease delayed-release capsules by mouth with each meal or snack as directed by your doctor. Do not take without food.
- Swallow amylase/lipase/protease delayed-release capsules whole with enough liquid to swallow it completely. Do not break, crush, chew, or hold amylase/lipase/protease delayed-release capsules in your mouth before swallowing. Doing so may increase the risk of mouth or tongue irritation from amylase/lipase/protease delayed-release capsules. Follow with a glass of water or juice. Contact your doctor if you experience mouth or tongue irritation while taking amylase/lipase/protease delayed-release capsules.
- If you cannot swallow the capsule whole, you may open it and sprinkle the contents over soft, bland food. Do NOT crush or chew the contents of the capsule. Ask your doctor or pharmacist if you have questions about what kind of food can be mixed with amylase/lipase/protease delayed-release capsules.
- If you mix the medicine with food, swallow the entire mixture right away. Do not save it for use at a later time. Drink a glass of water or juice after you swallow the mixture.
- Continue to take amylase/lipase/protease delayed-release capsules even if you feel well. Do not miss any doses.
- If you miss a dose of amylase/lipase/protease delayed-release capsules, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once or take a dose without a snack or a meal.
Ask your health care provider any questions you may have about how to use amylase/lipase/protease delayed-release capsules.
Important safety information:
- Do NOT take more than the recommended dose without checking with your doctor.
- Do not switch between amylase/lipase/protease delayed-release capsules and another pancreatic enzyme medicine without first checking with your doctor.
- Amylase/lipase/protease delayed-release capsules may increase the risk of developing a rare, serious condition called fibrosing colonopathy. When this occurs, it is usually with high doses over a long period of time. It has been most commonly reported in children with cystic fibrosis. Contact your doctor right away if you experience unusual or severe nausea, vomiting, or stomach pain; stomach bloating; or severe or persistent loose stools, constipation, or diarrhea.
- Amylase/lipase/protease delayed-release capsules comes from pork (pig) pancreas tissue. There is an extremely rare risk of developing a viral disease from this product. No cases of viral disease from pork pancreas products have been identified.
- Diabetes patients - Amylase/lipase/protease delayed-release capsules may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Caution is advised when using amylase/lipase/protease delayed-release capsules in CHILDREN; they may be more sensitive to its effects, especially fibrosing colonopathy.
- PREGNANCY and BREAST-FEEDING: It is not known if amylase/lipase/protease delayed-release capsules can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using amylase/lipase/protease delayed-release capsules while you are pregnant. It is not known if amylase/lipase/protease delayed-release capsules is found in breast milk. If you are or will be breast-feeding while you use amylase/lipase/protease delayed-release capsules, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of amylase/lipase/protease delayed-release capsules:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; gas; mild diarrhea; nausea; stomach cramps or pain; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); mouth irritation; painful, swollen joints; severe or persistent loose stools, diarrhea, or constipation; severe or unusual nausea, vomiting, or stomach pain; stomach bloating.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea.Proper storage of amylase/lipase/protease delayed-release capsules:
Store amylase/lipase/protease delayed-release capsules at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Do not refrigerate. Store away from heat, moisture, and light. Do not store in the bathroom. Keep amylase/lipase/protease delayed-release capsules out of the reach of children and away from pets.
- If you have any questions about amylase/lipase/protease delayed-release capsules, please talk with your doctor, pharmacist, or other health care provider.
- Amylase/lipase/protease delayed-release capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take amylase/lipase/protease delayed-release capsules or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about amylase/lipase/protease delayed-release capsules. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to amylase/lipase/protease delayed-release capsules. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using amylase/lipase/protease delayed-release capsules.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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