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Active substance(s): PARACETAMOL

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2. Check before you take Panadol Advance
500 mg Tablets
Do not take Panadol Advance 500 mg Tablets:
• if you have ever had an allergic reaction to paracetamol or to any of the
other ingredients (listed in Section 6)
• if you are taking other medicines containing paracetamol.

Ask your doctor before you take this medicine:
• if you have liver or kidney disease, including alcoholic liver disease
• if you suffer from mild arthritis and need to take painkillers every day.
Please read right through this leaflet before you start using this medicine.
This medicine is available without prescription, but you still need to use
Panadol Advance 500 mg Tablets carefully to get the best results from them.
• Keep this leaflet, you may need to read it again.
• If you have any questions, or if there is anything you do not understand,
ask your pharmacist.

In this leaflet:

What Panadol Advance 500 mg Tablets do
Check before you take Panadol Advance 500 mg Tablets
How to take Panadol Advance 500 mg Tablets
Possible side effects
How to store Panadol Advance 500 mg Tablets
Further information

1. What Panadol Advance 500 mg Tablets do

Panadol Advance 500 mg Tablets are faster absorbed than standard
paracetamol tablets. They are suitable for the relief of headache, tension
headache, migraine, backache, rheumatic and muscle pain, toothache and
period pain.
They also relieve sore throat and the fever, aches and pains of colds and flu
and are recommended for the relief of pain due to mild arthritis.
The active ingredient is paracetamol which is a painkiller and also reduces
your temperature when you have a fever.

If you are taking other medicines
Talk to your doctor or pharmacist before taking these tablets if you are
taking any prescribed medicines; particularly metoclopramide or
domperidone (for nausea [feeling sick] or vomiting [being sick]) or
colestyramine (to lower blood cholesterol). If you take blood thinning drugs
(anticoagulants e.g. warfarin) and you need to take a pain reliever on a daily
basis, talk to your doctor because of the risk of bleeding. But you can still
take occasional doses of Panadol Advance 500 mg Tablets at the same time as

Pregnancy and breast feeding
Talk to your doctor before taking Panadol Advance 500 mg Tablets if you are
pregnant. You can take this product whilst breast feeding.

3. How to take Panadol Advance 500 mg Tablets
Adults and children aged 12 years and over:
Swallow 2 tablets every 4 hours as needed.
Do not take more than 8 tablets in 24 hours.
Children aged 6 to 12 years:
Give ½ to 1 tablet every 4 hours as needed.
Do not give more than 4 tablets in 24 hours.
Do not give for more than 3 days at a time unless your doctor tells
you to.
• Do not take more frequently than every 4 hours.
• Do not take more than the recommended dose.
• Do not give to children under 6 years.

If you take too many tablets

Immediate medical advice should be sought in the event of an overdose,
even if you feel well, because of the risk of delayed, serious liver damage.
If your symptoms continue or your headache becomes persistent, see your

6. Further information

Active ingredient: Each tablet contains Paracetamol 500 mg.
Other ingredients: Pregelatinised starch, calcium carbonate, alginic acid,
crospovidone, povidone, magnesium stearate, colloidal anhydrous silica and
sodium methyl (E 219), sodium ethyl (E 215) and sodium propyl (E 217)
The tablet coating contains opadry white and carnauba wax.
The parahydroxybenzoates may cause allergic reactions (possibly delayed).
Packs of Panadol Advance 500 mg Tablets contain 16 or 32 tablets.
The marketing authorisation holder is GlaxoSmithKline Consumer Healthcare,
Brentford, TW8 9GS, U.K. and all enquiries should be sent to this address.
The manufacturer is Omega Pharma Manufacturing GmbH & Co. KG,
Benzstraße 25, 71083 Herrenberg, Germany.
This leaflet was last revised in July 2012.
Panadol and Advance are trade marks of the GlaxoSmithKline group of

4. Possible side effects

Like all medicines, Panadol Advance 500 mg Tablets can have side effects but
not everybody gets them. A small number of people have had side effects.
Stop taking the medicine and tell your doctor immediately if you experience:
• Allergic reactions which may be severe such as skin rash and itching
sometimes with swelling of the mouth or face or shortness of breath
• Skin rash or peeling, or mouth ulcers
• Breathing problems. These are more likely if you have experienced them
before when taking other painkillers such as ibuprofen and aspirin
• Unexplained bruising or bleeding
• Nausea, sudden weight loss, loss of appetite and yellowing of the eyes
and skin.
If you do get any side effects, even those not mentioned in this leaflet, tell
your doctor or pharmacist.

5. How to store Panadol Advance 500 mg Tablets
Keep out of the reach and sight of children.
Do not use this medicine after the ‘EXP’ date shown on the pack.


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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.