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Beta-lactamase inhibitors

What are Beta-lactamase inhibitors

Beta-lactamase inhibitors block the activity of beta-lactamase enzymes.

Some species of bacteria produce beta-lactamase enzymes, which cleave the beta-lactam group in antibiotics, such as penicillin, that have a beta-lactam ring in their structure. In doing so the beta-lactamase enzyme inactivates the antibiotic and becomes resistant to that antibiotic. To avoid development of resistance, beta-lactamase inhibitors are administered with the beta-lactam antibiotics so the action of beta-lactamase is inhibited. This tends to widen the spectrum of antibacterial activity.

List of Beta-lactamase inhibitors:

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Drug Name DownUp( View by: Brand | Generic ) Reviews Ratings DownUp
ampicillin / sulbactam systemic (Pro, More...)
2 reviews
   
8.5
piperacillin / tazobactam systemic (Pro, More...)
5 reviews
   
7.5
amoxicillin / clavulanate systemic (Pro, More...)
378 reviews
   
6.2
clavulanate / ticarcillin systemic (Pro, More...)
0 reviews
   
4.5
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