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Skinvive by Juvéderm

Generic name: hyaluronic acid/lidocaine systemic
Dosage form: injectable gel (intradermal microdroplet)

Medically reviewed by Melisa Puckey, BPharm. Last updated on May 30, 2023.

What is Skinvive by Juvéderm?

Skinvive by Juvéderm is a hyaluronic acid dermal filler used to improve skin smoothness of the cheeks, it is given by intradermal microdroplet injection. Skinvive by Juvéderm injection has been FDA-approved for patients 21 years and older, and clinical trials participants were from every Fitzpatrick Skin Type (I-VI), from the lightest to the darkest. Skinvive by Juvéderm also contains the local anesthetic lidocaine for a more comfortable injection as this numbs the treatment area within seconds.

Dermal filler injections are a nonsurgical cosmetic procedure used to plump up wrinkles, smooth lines, and restore volume in your face. A dermal filler is injected under your skin by healthcare professionals who have had appropriate training, experience, and who are knowledgeable about the anatomy of the site being treated.

Who should not use Skinvive by Juvéderm 

Skinvive should not be use in patients with

Skinvive is FDA-approved for patients over the age of 21.

Treatment with Skinvive should be deferred if the site to be treated is inflamed or if there are skin eruptions such as cysts, pimples, rashes, or hives. 

What should I tell my doctor before receiving Skinvive by Juvéderm

Tell your healthcare professional if you:

Pregnancy and breastfeeding

The safety for use during pregnancy and in breastfeeding females has not been established. 

How will I receive Skinvive by Juvéderm?

Skinvive by Juvéderm will be given as an intradermal microdroplet injection by a fully trained healthcare provider. Microdroplet injections are a very small volume of gel (0.01 mL to 0.05 mL) that are spaced approximately 0.5 cm to 1 cm apart; however, placement and volume will vary based on the patient’s treatment goals. 

Dosing information

The typical volume to achieve optimal improvement in skin smoothness of the cheeks is 4.0 mL.

Injection volumes after repeat treatment tended to be lower, with the typical injection volume to maintain optimal effect being 2.7 mL. 

What should I avoid while receiving Skinvive by Juvéderm?

Avoid applying makeup for 12 hours after treatment, and within the first 24 hours, patients should avoid strenuous exercise, extensive sun or heat exposure, and alcoholic beverages. Exposure to any of the above may cause temporary redness, swelling, and/or itching at the injection sites.

What are the other Juvéderm products?

​​The Juvéderm range of products are designed to meet specific needs depending on the area of the face being treated and increase in the volume required.

Juvederm XC products also contain the local anesthetic lidocaine for a more comfortable injection as this numbs the treatment area within seconds. The Juvederm Ultra XC products contain more highly cross-linked formulations for volumizing and correction of deeper folds and wrinkles.

What are the side effects of Skinvive?

Skinvive Injection site side effects include:

Injection site responses consist mainly of short-term inflammatory symptoms and generally resolve within 1 week

Serious side effects.

Skinvive must not be injected into blood vessels as this may lead to embolization, occlusion of the vessels, ischemia, or infarction. If this occurs rare but serious adverse events can occur and have been reported. These include temporary or permanent vision impairment, blindness, cerebral ischemia or cerebral hemorrhage leading to stroke, skin necrosis, and damage to underlying facial structures. Immediately stop the injection if a patient exhibits any of the following symptoms, including changes in vision, signs of a stroke, blanching of the skin, or unusual pain during or shortly after the procedure. Patients should receive prompt medical attention and possibly evaluation by an appropriate health care professional specialist should an intravascular injection occur.

Storage

Ingredients

Skinvive by Juvéderm contains hyaluronic acid (HA) produced by Streptococcus species of bacteria crosslinked with 1,4-butanediol diglycidyl (BDDE) formulated to a concentration of 12 mg/mL with 0.3% w/w lidocaine in a physiologic buffer.

Company

Allergan Aesthetics, an AbbVie company. Irvine, CA 92612 USA 1-800-624-426

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.