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Dysport

Generic Name: abobotulinumtoxinA (A boe BOT ue LYE num TOX in A)
Brand Names: Dysport

What is Dysport?

Dysport is an injection containing abobotulinumtoxinA (Botulinum toxin type A). AbobotulinumtoxinA is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity.

Dysport is used to treat cervical dystonia (severe spasms in the neck muscles).

Dysport is also used to temporarily lessen the appearance of facial wrinkles.

Important information

The botulinum toxin contained in Dysport can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving Dysport, even for cosmetic purposes.

You should not receive Dysport if you are allergic to botulinum toxin or cow's milk, or if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected.

Call your doctor at once if you have a hoarse voice, drooping eyelids, vision problems, severe muscle weakness, loss of bladder control, or trouble breathing, talking, or swallowing. Some of these effects can occur up to several weeks after receiving a Dysport injection. This injection should be given only by a trained medical professional, even when used for cosmetic purposes. Botox is another brand of botulinum toxin injection. Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injectio.

Before receiving Dysport injection, tell your doctor if you have ALS (Lou Gehrig's disease), myasthenia gravis, Lambert-Eaton syndrome, a breathing disorder, trouble swallowing, facial muscle weakness, a change in the appearance of your face, seizures, bleeding problems, heart disease, diabetes, if you have had or will have surgery, or if you have ever received other botulinum toxin injections such as Botox or Myobloc.

The effects of Dysport injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.

Before taking this medicine

You should not receive Dysport injecton if you are allergic to botulinum toxin or cow's milk, or if you have an infection, swelling, or muscle weakness in the area where the medicine will be injected. Tell your doctor if you have ever had a side effect after receiving a botulinum toxin in the past

To make sure Dysport is safe for you, tell your doctor if you have:

  • amyotrophic lateral sclerosis (ALS, or "Lou Gehrig's disease");

  • myasthenia gravis;

  • Lambert-Eaton syndrome;

  • a breathing disorder such as asthma or emphysema;

  • problems with swallowing;

  • facial muscle weakness (droopy eyelids, weak forehead, trouble raising your eyebrows);

  • a change in the normal appearance of your face;

  • a seizure disorder;

  • bleeding problems;

  • heart disease;

  • diabetes;

  • if you have had or plan to have surgery (especially on your face); or

  • if you have ever received other botulinum toxin injections such as Botox or Myobloc (especially in the last 4 months).

AbobotulinumtoxinA is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Dysport will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether abobotulinumtoxinA passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby while receiving Dysport.

How is Dysport given?

Dysport is injected into a muscle. A doctor, nurse, or other healthcare provider will give you this injection. Botulinum toxin injections should be given only by a trained medical professional, even when used for cosmetic purposes.

Dysport injections should be spaced at least 3 months apart.

Your injection may be given into more than one area at a time, depending on the condition being treated.

The effects of a Dysport injection are temporary. Your symptoms may return completely within 3 months after an injection. After repeat injections, it may take less and less time before your symptoms return, especially if your body develops antibodies to the botulinum toxin.

Do not seek botulinum toxin injections from more than one medical professional at a time. If you switch healthcare providers, be sure to tell your new provider how long it has been since your last botulinum toxin injection.

Using Dysport more often than prescribed will not make it more effective and may result in serious side effects.

See also: Dosage Information (in more detail)

What happens if I miss a dose?

Since botulinum toxin has a temporary effect and is given at widely spaced intervals, missing a dose is not likely to be harmful.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may not appear right away, but can include muscle weakness, trouble swallowing, and weak or shallow breathing.

What should I avoid after receiving Dysport?

Dysport may impair your vision or depth perception. Be careful if you drive or do anything that requires you to be able to see clearly.

Avoid going back to your normal physical activities too quickly after receiving an injection.

Dysport side effects

Get emergency medical help if you have signs of an allergic reaction to Dysport: hives; difficulty breathing; feeling like you might pass out; swelling of your face, lips, tongue, or throat.

The botulinum toxin contained in Dysport can spread to other body areas beyond where it was injected. This has caused serious life-threatening side effects in some people receiving botulinum toxin injections, even for cosmetic purposes.

Call your doctor at once if you have any of these side effects, some of which can occur up to several weeks after receiving a Dysport injection:

  • trouble breathing, talking, or swallowing;

  • hoarse voice, drooping eyelids;

  • problems with vision;

  • unusual or severe muscle weakness (especially in a body area that was not injected with the medication);

  • loss of bladder control;

  • crusting or drainage from your eyes;

  • severe skin rash or itching;

  • fast, slow, or uneven heartbeats; or

  • chest pain or heavy feeling, pain spreading to the arm or shoulder, general ill feeling.

Common Dysport side effects may include:

  • muscle weakness near where the medicine was injected;

  • bruising, bleeding, pain, redness, or swelling where the injection was given;

  • headache, muscle pain or stiffness, neck pain;

  • fever, cough, sore throat, runny or stuffy nose;

  • drooping eyelids, dry or puffy eyes;

  • nausea, dry mouth;

  • trouble swallowing; or

  • tired feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Dysport?

Other drugs can increase some of the side effects of Dysport, including cold or allergy medicine, muscle relaxers, sleeping pills, bronchodilators, bladder or urinary medicines, and irritable bowel medicines. Tell your doctor if you regularly use any of these medicines.

Tell your doctor about all your current medicines and any you start or stop using, especially:

  • an injected antibiotic-- amikacin, gentamicin, kanamycin, neomycin, paromomycin, streptomycin, tobramycin.

This list is not complete. Other drugs may interact with abobotulinumtoxinA, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Do not start a new medication without telling your doctor that you have received Dysport in the past.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about Dysport.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Dysport only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2016 Cerner Multum, Inc. Version: 4.01. Revision Date: 2015-09-14, 2:08:09 PM.

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