Valturna Side Effects
Generic Name: aliskiren / valsartan
Note: This page contains side effects data for the generic drug aliskiren / valsartan. It is possible that some of the dosage forms included below may not apply to the brand name Valturna.
It is possible that some side effects of Valturna may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to aliskiren / valsartan: oral tablet
As well as its needed effects, aliskiren / valsartan may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking aliskiren / valsartan, check with your doctor immediately:Less common
- Bladder pain
- bloody or cloudy urine
- body aches or pain
- difficult, burning, or painful urination
- difficulty breathing
- ear congestion
- frequent urge to urinate
- general feeling of discomfort or illness
- joint pain
- loss of appetite
- loss of voice
- lower back or side pain
- muscle aches and pains
- nasal congestion
- runny nose
- sore throat
- trouble sleeping
- unusual tiredness or weakness
- Blurred vision
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- Abdominal or stomach pain
- irregular heartbeat
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- numbness or tingling in the hands, feet, or lips
- shortness of breath
- weakness or heaviness of the legs
Some aliskiren / valsartan side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:Less common
- Feeling of constant movement of self or surroundings
- sensation of spinning
For Healthcare Professionals
Applies to aliskiren / valsartan: oral tablet
Genitourinary side effects have included urinary tract infection (1.4%). Genitourinary side effects reported for the aliskiren component have included elevated uric acid (0.4%), gout (0.2%), and renal stones (0.2%). Genitourinary side effects reported for the valsartan component have included impotence.[Ref]
Nervous system side effects have included fatigue (2.6%) and vertigo (1.1%). Nervous system side effects reported for the aliskiren component have included headache, dizziness, fatigue, cough, and tonic-clonic seizures in two patients, one of which had a history of seizures and the other had no history given.[Ref]
Gastrointestinal side effects have included diarrhea (1.4%). Gastrointestinal side effects reported for the aliskiren component have included diarrhea which increased with increasing dosage and was higher in elderly women, abdominal pain, dyspepsia, and gastroesophageal reflux.[Ref]
Immunologic side effects have included nasopharyngitis (2.6%) and upper respiratory tract infection (1.1%). Immunologic side effects reported for the aliskiren component have included nasopharyngitis and upper respiratory tract infection. There have been postmarketing reports of angioedema requiring airway management and hospitalization associated with aliskiren.[Ref]
Ocular side effects reported for the aliskiren component have included periorbital edema without respiratory symptoms.[Ref]
General side effects reported for the aliskiren component have included angioedema (0.06%), and edema involving the face, hands, or whole body (0.4%), and cough (1.1%). General side effects reported for the valsartan component have included cough (2.6%), and angioedema.[Ref]
Local side effects reported for the aliskiren component have included rash (1%).[Ref]
Musculoskeletal side effects reported for the aliskiren component have included back pain. Musculoskeletal side effects reported for the valsartan component have included asthenia and muscle cramps.[Ref]
Psychiatric side effects reported for the valsartan component have included paresthesia.[Ref]
Respiratory side effects reported for the valsartan component have included sinusitis and pharyngitis.[Ref]
Hematologic side effects have included small mean decreases from baseline in red blood cell (RBC) count, hemoglobin, and hematocrit in both monotherapy and combination therapy.
Postmarketing hematologic side effects have included increased blood creatinine.[Ref]
Hepatic side effects have included elevations in blood urea nitrogen (BUN) and creatinine (less than 1%).[Ref]
There have been postmarketing reports of peripheral edema associated with aliskiren.
Postmarketing reports have included severe cutaneous adverse reactions, including Stevens Johnson syndrome and toxic epidermal necrolysis.
1. "Product Information. Diovan (valsartan)." Novartis Pharmaceuticals, East Hanover, NJ.
2. "Product Information. Tekturna (aliskiren)." Novartis Pharmaceuticals, East Hanover, NJ.
3. "Product Information. Valturna (aliskiren-valsartan)." Novartis Pharmaceuticals, East Hanover, NJ.
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