Tranxene Side Effects
Generic name: clorazepate
Note: This document contains side effect information about clorazepate. Some of the dosage forms listed on this page may not apply to the brand name Tranxene.
Some side effects of Tranxene may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to clorazepate: oral capsule, oral tablet, oral tablet extended release
Along with its needed effects, clorazepate (the active ingredient contained in Tranxene) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking clorazepate:Less common
- Bladder pain
- bloody or cloudy urine
- difficult, burning, or painful urination
- frequent urge to urinate
- lower back or side pain
- shakiness and unsteady walk
- slurred speech
- trembling or shaking of the hands or feet
- unsteadiness, trembling, or other problems with muscle control or coordination
Get emergency help immediately if any of the following symptoms of overdose occur while taking clorazepate:Symptoms of overdose
- Change in consciousness
- loss of consciousness
- relaxed and calm
Some side effects of clorazepate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common
- Blurred vision
- double vision
- dry mouth
- feeling sad or empty
- loss of appetite
- loss of interest or pleasure
- mental confusion
- nausea or vomiting
- passing of gas
- seeing double
- skin rash
- stomach pain, fullness, or discomfort
- trouble with concentrating
- trouble with sleeping
- unable to sleep
- unusual tiredness or weakness
For Healthcare Professionals
Applies to clorazepate: oral tablet
Nervous system side effects have been common and including drowsiness, dizziness, nervousness, fatigue, confusion, and headache. Less common nervous system effects have included insomnia, irritability, delirium, diplopia, depression, tremor, and slurred speech. A case of a rage reaction has been associated with clorazepate (the active ingredient contained in Tranxene) therapy.
Other side effects have included withdrawal symptoms after abrupt cessation of clorazepate (the active ingredient contained in Tranxene) These have included agitation, restlessness, nervousness, anxiety, insomnia, convulsions, tremor, nausea, headache and sweating.
Respiratory side effects including respiratory depression is theoretically possible and has been reported during therapy with other benzodiazepines.
Hepatic side effects have included a case of jaundice followed by focal hepatocellular necrosis.
Dermatologic side effects including a case of photo-onycholysis has been reported in association with clorazepate (the active ingredient contained in Tranxene) therapy. Another case of skin blistering in association with an overdose of amitriptyline and clorazepate has also been reported.
More Tranxene resources
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