Tranxene Side Effects
Generic Name: clorazepate
Note: This page contains side effects data for the generic drug clorazepate. It is possible that some of the dosage forms included below may not apply to the brand name Tranxene.
It is possible that some side effects of Tranxene may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to clorazepate: oral capsule, oral tablet, oral tablet extended release
As well as its needed effects, clorazepate (the active ingredient contained in Tranxene) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking clorazepate, check with your doctor immediately:Less common
- Bladder pain
- bloody or cloudy urine
- difficult, burning, or painful urination
- frequent urge to urinate
- lower back or side pain
- shakiness and unsteady walk
- slurred speech
- trembling or shaking of the hands or feet
- unsteadiness, trembling, or other problems with muscle control or coordination
If any of the following symptoms of overdose occur while taking clorazepate, get emergency help immediately:Symptoms of overdose
- Change in consciousness
- loss of consciousness
- relaxed and calm
Some clorazepate side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:Less common
- Blurred vision
- double vision
- dry mouth
- feeling sad or empty
- loss of appetite
- loss of interest or pleasure
- mental confusion
- nausea or vomiting
- passing of gas
- seeing double
- skin rash
- stomach pain, fullness, or discomfort
- trouble with concentrating
- trouble with sleeping
- unable to sleep
- unusual tiredness or weakness
For Healthcare Professionals
Applies to clorazepate: oral tablet
Nervous system side effects have been common and including drowsiness, dizziness, nervousness, fatigue, confusion, and headache. Less common nervous system effects have included insomnia, irritability, delirium, diplopia, depression, tremor, and slurred speech. A case of a rage reaction has been associated with clorazepate (the active ingredient contained in Tranxene) therapy.
Other side effects have included withdrawal symptoms after abrupt cessation of clorazepate (the active ingredient contained in Tranxene) These have included agitation, restlessness, nervousness, anxiety, insomnia, convulsions, tremor, nausea, headache and sweating.
Respiratory side effects including respiratory depression is theoretically possible and has been reported during therapy with other benzodiazepines.
Hepatic side effects have included a case of jaundice followed by focal hepatocellular necrosis.
Dermatologic side effects including a case of photo-onycholysis has been reported in association with clorazepate (the active ingredient contained in Tranxene) therapy. Another case of skin blistering in association with an overdose of amitriptyline and clorazepate has also been reported.
More about Tranxene (clorazepate)
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