Skip to Content

Clorazepate Pregnancy and Breastfeeding Warnings

Clorazepate is also known as: Tranxene, Tranxene SD, Tranxene T-Tab

Clorazepate Pregnancy Warnings

Use should be avoided. US FDA pregnancy category: Not assigned Comments: -The child born to a mother taking benzodiazepines may be at risk for withdrawal symptoms. -Benzodiazepines may cause fetal harm when administered during pregnancy. -The patient should be warned of the potential risks to the fetus and instructed to discontinue the drug prior to becoming pregnant.

Several studies have suggested an increased risk of congenital malformations associated with the use of minor tranquilizers (i.e., chlordiazepoxide, diazepam, meprobamate) during the first trimester of pregnancy. There are no adequate studies in pregnant women. US: To provide information regarding the effects of in utero exposure to this drug, healthcare providers are advised to recommend that pregnant patients taking this drug enroll in the North American Anti-epileptic Drug (NAAED) Pregnancy Registry. Patients can call the toll-free number 1-888-233-2334. Information on the registry can also be found at the website US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decision and counsel women about the use of drugs during pregnancy. Pregnancy categories A, B, C, D and X are being phased out.

See references

Clorazepate Breastfeeding Warnings

Use is not recommended. Excreted into human milk: Yes Comments: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Tranxene (clorazepate)." Abbott Pharmaceutical, Abbott Park, IL.

References for breastfeeding information

  1. "Product Information. Tranxene (clorazepate)." Abbott Pharmaceutical, Abbott Park, IL.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.