Tradjenta Side Effects

Generic Name: linagliptin

Note: This document contains side effect information about linagliptin. Some of the dosage forms listed on this page may not apply to the brand name Tradjenta.

Some side effects of Tradjenta may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to linagliptin: oral tablet

Along with its needed effects, linagliptin (the active ingredient contained in Tradjenta) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking linagliptin:

More common
  • Anxiety
  • blurred vision
  • chills
  • cold sweats
  • coma
  • confusion
  • cool, pale skin
  • depression
  • dizziness
  • fast heartbeat
  • headache
  • increased hunger
  • nausea
  • nightmares
  • seizures
  • shakiness
  • slurred speech
  • unusual tiredness or weakness
Rare
  • Bloating
  • constipation
  • darkened urine
  • fever
  • indigestion
  • loss of appetite
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • vomiting
  • yellow eyes or skin
Incidence not known
  • Flaking and falling off of the skin
  • hives or welts
  • itching
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • redness of the skin
  • skin rash

Some side effects of linagliptin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Back pain
  • difficulty with moving
  • muscle aches
  • muscle pain or stiffness
  • pain in the joints
  • sore throat
  • stuffy or runny nose
Less common
  • Cough
  • weight gain

For Healthcare Professionals

Applies to linagliptin: oral tablet

Metabolic

Metabolic side effects have included hypoglycemia, hyperlipidemia, hypertriglyceridemia and weight gain.

Hypersensitivity

Hypersensitivity side effects have included urticaria, angioedema, localized skin exfoliation, and bronchial hyperreactivity.

Respiratory

Respiratory side effects have included nasopharyngitis and cough. Side effects reported when linagliptin (the active ingredient contained in Tradjenta) was used in combination with glimepiride and metformin include upper respiratory infection.

Musculoskeletal

Musculoskeletal side effects have included arthralgia, back pain and myalgia. Side effects reported when linagliptin (the active ingredient contained in Tradjenta) was used in combination with glimepiride and metformin include pain in extremities.

Endocrine

Endocrine side effects have included pancreatitis.

Nervous system

Nervous system side effects have included headache.

Gastrointestinal

Gastrointestinal side effects reported include diarrhea. Side effects reported when linagliptin (the active ingredient contained in Tradjenta) was added on to basal insulin therapy include constipation.

Genitourinary

Genitourinary side effects reported when linagliptin (the active ingredient contained in Tradjenta) was used in combination with specific anti-diabetic agents include urinary tract infection.

Other

Increases in uric acid were reported more frequently in patients treated with linagliptin (the active ingredient contained in Tradjenta) than placebo.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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