Tenuate Dospan Side Effects

Generic Name: diethylpropion

Note: This document contains side effect information about diethylpropion. Some of the dosage forms listed on this page may not apply to the brand name Tenuate Dospan.

Some side effects of Tenuate Dospan may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to diethylpropion: oral tablet, oral tablet extended release

Along with its needed effects, diethylpropion (the active ingredient contained in Tenuate Dospan) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking diethylpropion:

Rare
  • Seeing, hearing, or feeling things that are not there
  • severe mental changes
  • shortness of breath
Incidence not known
  • Black, tarry stools
  • blurred vision
  • burning while urinating
  • chest pain
  • chills
  • convulsions
  • cough or hoarseness
  • decreased ability to exercise
  • depression
  • difficult or labored breathing
  • difficult or painful urination
  • dizziness
  • fainting
  • false or unusual sense of well-being
  • fast, slow, pounding, or irregular heartbeat or pulse
  • fear or nervousness
  • fever with or without chills
  • frequent urination
  • general feeling of tiredness or weakness
  • headache
  • inability to speak
  • increased volume of pale, dilute urine
  • lower back or side pain
  • nosebleeds
  • numbness or tingling in the face, arms, or legs
  • restlessness
  • severe or sudden headache
  • shakiness in the legs, arms, hands, or feet
  • slurred speech
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swelling of the feet or lower legs
  • swollen glands
  • temporary blindness
  • tightness in the chest
  • trembling or shaking of the hands or feet
  • trouble with breathing
  • twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • vision problems
  • weakness in the arm or leg on one side of the body, sudden and severe
  • wheezing

Get emergency help immediately if any of the following symptoms of overdose occur while taking diethylpropion:

Symptoms of overdose
  • Abdominal or stomach cramps
  • bigger, dilated, or enlarged pupils (black part of the eye)
  • change in consciousness
  • confusion
  • diarrhea
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • increased sensitivity of the eyes to light
  • loss of consciousness
  • nausea
  • overactive reflexes
  • panic
  • physical attempt to injure
  • restlessness
  • sweating
  • violent actions
  • vomiting

Some side effects of diethylpropion may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
  • Abdominal or stomach discomfort
  • bruising
  • difficulty having a bowel movement (stool)
  • drowsiness
  • dry mouth
  • general feeling of discomfort or illness
  • hair loss
  • headache
  • hives or welts
  • indigestion
  • itching
  • large, flat, blue, or purplish patches in the skin
  • loss of appetite
  • muscle pain
  • passing of gas
  • redness of the skin
  • skin rash
  • sleeplessness
  • stomach fullness or discomfort
  • trouble sleeping
  • unable to sleep
  • unpleasant taste

For Healthcare Professionals

Applies to diethylpropion: oral tablet, oral tablet extended release

Cardiovascular

Cardiovascular side effects including precordial pain, arrhythmia, ECG changes, tachycardia, elevation of blood pressure, and palpitation have been reported. Pulmonary hypertension has been reported rarely. Valvulopathy has been reported very rarely.

A causal relationship between diethylpropion and valvulopathy has not been reported. Valvular heart disease has been reported with the use of other anorectic agents.

Nervous system

Nervous system side effects including dyskinesia, blurred vision, overstimulation, nervousness, restlessness, dizziness, jitteriness, insomnia, anxiety, euphoria, depression, dysphoria, tremor, mydriasis, drowsiness, malaise, headache, and cerebrovascular accident have been reported. Psychotic episodes have rarely been reported (at recommended doses). An increase in convulsive episodes has been reported in a few epileptics.

Respiratory

Respiratory side effects including dyspnea have been reported. One study has reported that the use of anorectic agents including diethylpropion (the active ingredient contained in Tenuate Dospan) for longer than three months was associated with a 23-fold increase in the risk of developing pulmonary hypertension.

Psychiatric

Psychiatric side effects including psychological dependence and psychosis have been reported.

Gastrointestinal

Gastrointestinal side effects including vomiting, diarrhea, abdominal discomfort, dryness of the mouth, unpleasant taste, nausea, constipation, and other gastric disturbances have been reported.

Dermatologic

Dermatologic side effects including urticaria, rash, ecchymosis, erythema, hair loss, and increased sweating have been reported.

Endocrine

Endocrine side effects including impotence, changes in libido, gynecomastia, and menstrual upset have been reported.

Hematologic

Hematologic side effects including bone marrow depression, agranulocytosis, and leukopenia have been reported.

Genitourinary

Genitourinary side effects including dysuria and polyuria have been reported. Two cases of gynecomastia have also been reported.

Musculoskeletal

Musculoskeletal side effects including muscle pain have been reported.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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