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Tafluprost ophthalmic Side Effects

It is possible that some side effects of tafluprost ophthalmic may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to tafluprost ophthalmic: ophthalmic solution

As well as its needed effects, tafluprost ophthalmic may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking tafluprost ophthalmic, check with your doctor immediately:

Less common
  • Blurred vision
  • burning, dry, or itching eyes
  • decreased vision
  • eye discharge or excessive tearing
  • eye pain
  • redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid

Some tafluprost ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Headache
  • stinging or irritation of the eye
Less common
  • Cough
  • darker color of the eyelashes
  • dry eyes
  • increased growth of the eyelashes

For Healthcare Professionals

Applies to tafluprost ophthalmic: ophthalmic solution


Common (1% to 10%): Ocular stinging/irritation, ocular pruritus including allergic conjunctivitis, cataract, dry eye, ocular pain, eyelash darkening, growth of eyelashes, blurred vision, increased lacrimation, eyelid erythema, foreign body sensation in the eyes, photophobia, reduced visual acuity, punctate keratitis, eye discharge, eyelid edema, iris hyperpigmentation, conjunctival/ocular hyperemia
Uncommon (0.1 to 1%): Blepharal pigmentation, asthenopia, conjunctival edema, blepharitis, anterior chamber cells, ocular discomfort, anterior chamber flare, conjunctival pigmentation, conjunctival follicles, allergic conjunctivitis
Very rare (less than 0.01%): Corneal calcification (in association with the use of phosphate containing eye drops in some patients with significantly damaged corneas)
Frequency not reported: Deepening of the eyelid sulcus, iritis/uveitis[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]


The most commonly reported side effect was conjunctival/ocular hyperemia.[Ref]


Common (1% to 10%): Urinary tract infection[Ref]


Common (1% to 10%): Cough
Postmarketing reports: Exacerbation of asthma, dyspnea[Ref]


Uncommon (0.1% to 1%): Hypertrichosis of the eyelid[Ref]


Common (1% to 10%): Common cold[Ref]


1. "Product Information. Zioptan (tafluprost ophthalmic)." Merck & Company Inc, Whitehouse Station, NJ.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. Cerner Multum, Inc. "Australian Product Information." O 0

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