Stendra Side Effects

Generic Name: avanafil

Note: This page contains side effects data for the generic drug avanafil. It is possible that some of the dosage forms included below may not apply to the brand name Stendra.

It is possible that some side effects of Stendra may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to avanafil: oral tablet

As well as its needed effects, avanafil (the active ingredient contained in Stendra) may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking avanafil, check with your doctor immediately:

Less common
  • Blurred vision
  • dizziness
  • headache
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
Rare
  • Arm, back, or jaw pain
  • bladder pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or cloudy urine
  • chest pain or discomfort
  • chest tightness or heaviness
  • difficult or labored breathing
  • difficult, burning, or painful urination
  • fast, irregular, pounding, or racing heartbeat or pulse
  • frequent urge to urinate
  • increased erection
  • lower back or side pain
  • nausea and vomiting
  • pain in the groin or genitals
  • pain, redness, or swelling in the arm or leg
  • rapid weight gain
  • sharp back pain just below the ribs
  • shortness of breath
  • sweating
  • tightness in the chest
  • tingling of the hands or feet
  • unusual tiredness or weakness
  • unusual weight gain or loss

Some avanafil side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Feeling of warmth
  • fever
  • muscle aches
  • redness of the face, neck, arms, and occasionally, upper chest
  • sore throat
  • stuffy or runny nose
Less common
  • Acid or sour stomach
  • belching
  • body aches or pain
  • change in color vision
  • chills
  • cough
  • cough producing mucus
  • diarrhea
  • difficulty having a bowel movement (stool)
  • difficulty moving
  • ear congestion
  • heartburn
  • indigestion
  • joint pain
  • loss of appetite
  • loss of voice
  • muscle pain or stiffness
  • pain or tenderness around the eyes and cheekbones
  • rash
  • shivering
  • sneezing
  • sweating
  • trouble sleeping
Rare
  • Anxiety
  • bloody nose
  • bone pain
  • burning feeling in the chest or stomach
  • confusion
  • cool, pale skin
  • depression
  • feeling of constant movement of self or surroundings
  • increased hunger
  • itching skin
  • muscle aching or cramping
  • muscle spasms
  • nightmares
  • seizures
  • sensation of spinning
  • shakiness
  • sleepiness or unusual drowsiness
  • sleeplessness
  • slurred speech
  • swollen joints
  • tenderness in the stomach area
  • unable to sleep

For Healthcare Professionals

Applies to avanafil: oral tablet

General

The most common side effects reported were headache, flushing, nasal and sinus congestion and back pain.

Cardiovascular

Very common (10% or more): Flushing (up to 10.1%)
Common (1% to 10%): Hypertension, abnormal electrocardiogram
Uncommon (0.1% to 1%): Peripheral edema, angina, unstable angina, deep vein thrombosis, palpitations, hot flush, increased heart rate
Rare (less than 0.1%): Tachycardia, chest pain, increased blood pressure, cardiac murmur
Postmarketing reports: Hypotension

Genitourinary

Uncommon (0.1% to 1%): Balanitis, increased erection
Rare (less than 0.1%): Penis disorder, spontaneous penile erection, genital pruritus, increased prostate specific antigen
Postmarketing reports: Priapism, hematuria, hematospermia, penile hemorrhage

Dermatologic

Common (1% to 10%): Rash
Uncommon (0.1% to 1%): Pruritus

Gastrointestinal

Common (1% to 10%): Diarrhea, dyspepsia, nausea, constipation
Uncommon (0.1% to 1%): Gastritis, gastroesophageal reflux disease, stomach discomfort, vomiting, dyspepsia, nausea
Rare (less than 0.1%): Dry mouth, lower abdominal pain

Musculoskeletal

Common (1% to 10%): Back pain, arthralgia
Uncommon (0.1% to 1%): Muscle spasms, musculoskeletal pain, myalgia, pain in extremity, muscle tightness
Rare (less than 0.1%): Flank pain

Nervous system

Very common (10% or more): Headache (up to 12.1%)
Common (1% to 10%): Dizziness
Uncommon (0.1% to 1%): Somnolence, vertigo, sinus headache
Rare (less than 0.1%): Psychomotor hyperactivity

Psychiatric

Uncommon (0.1% to 1%): Depression, insomnia
Rare (less than 0.1%): Premature ejaculation, inappropriate affect

Renal

Uncommon (0.1% to 1%): Hematuria, nephrolithiasis, pollakiuria, urinary tract infection
Rare (less than 0.1%): Blood urine present

Respiratory

Common (1% to 10%): Nasal congestion, nasopharyngitis, upper respiratory infection (URI), bronchitis, sinusitis, sinus congestion
Uncommon (0.1% to 1%): Oropharyngeal pain, cough, exertional dyspnea, wheezing
Rare (less than 0.1%): Rhinorrhea, upper respiratory tract congestion

Hematologic

Uncommon (0.1% to 1%): Epistaxis

Hepatic

Uncommon (0.1% to 1%): Increased alanine aminotransferase
Rare (less than 0.1%): Increased blood bilirubin

Immunologic

Common (1% to 10%): Influenza
Rare (less than 0.1%): Seasonal allergy

Metabolic

Uncommon (0.1% to 1%): Hypoglycemia, increased blood glucose
Rare (less than 0.1%): Gout, Increased weight

Ocular

Uncommon (0.1% to 1%): Blurred vision, vision loss
Postmarketing reports: Non-arteritic anterior ischemic optic neuropathy (NAION)

Other

Uncommon (0.1% to 1%): Fatigue, tinnitus
Rare (less than 0.1%): Asthenia, influenza-like illness, increased body temperature
Postmarketing reports: Loss of hearing

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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